دورية أكاديمية
Evaluation of genotoxicity from Nilufer Stream (Bursa/Turkey) water using piscine micronucleus test
| العنوان: | Evaluation of genotoxicity from Nilufer Stream (Bursa/Turkey) water using piscine micronucleus test |
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| المساهمون: | Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., orcid:0000-0002-7687-3284, orcid:0000-0002-3595-6286, Summak, Şenay, Çinkılıç, Nilüfer, Vatan, Özgür, Yılmaz, Dilek, Zorlu, Tolga, Bilaloğlu, Rahmi, O-7508-2015, AAH-5296-2021, 36132176200, 26533892300, 16235098100, 6701369462, 36629756000, 6505804122 |
| بيانات النشر: | Pergamon-Elsevier |
| سنة النشر: | 2010 |
| المجموعة: | Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
| مصطلحات موضوعية: | Oreochromis niloticus (nile tilapia), Genotoxicity, Fish micronuclei, Nuclear abnormalities, Nilufer Stream, Fish-hoplias malabaricus, In situ, Aquatic environments, Heavy-metals, Comet assay, Biomarkers, River, Erythrocytes, Mutagenicity, Pollution, Food science & technology, Toxicology, Oreochromis niloticus, Pisces, Animals, Cell nucleus, Cichlids, Environmental monitoring, Hydrogen-ion concentration, Metals, heavy, Micronucleus tests, Mutagens, Oxygen, Turkey |
| الوصف: | In the present study, the in vivo micronucleus (MN) test in fish erythrocytes was used to evaluate the genotoxic potentials of water samples collected from four different sites along the Nilufer Stream which empties into the Marmara Sea on the north-west of Turkey. Nilufer Stream receives discharges of industrial and domestic wastes resulting from industrialization and urbanization activities in Bursa city. Nile tilapias (Oreochromis niloticus) were exposed to collected water samples under laboratory conditions for 3 and 6 days. Micronuclei analyses were carried out in peripheral blood erythrocytes. In addition to micronuclei, other nuclear abnormalities (NAs) such as bi-nucleated cells and binuclei with nucleoplasmic bridge and cells with blebbed, notched and lobbed nuclei, were assessed in the erythrocytes. Chemical analyses were also carried out in the water samples to assess the presence of major pollutants. MN and NA frequencies were significantly elevated in fishes exposed to water from polluted areas compared to those exposed to clean water sample. The results of this study indicate that Nilufer Stream is contaminated with potential genotoxic chemicals and the genotoxicity is possibly related with the industrial, agricultural and domestic activities. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0278-6915 1873-6351 |
| العلاقة: | Makale - Uluslararası Hakemli Dergi; Food and Chemical Toxicology; Summak, Ş. vd. (2010). "Evaluation of genotoxicity from Nilufer Stream (Bursa/Turkey) water using piscine micronucleus test". Food and Chemical Toxicology, 48(8-9), 2443-2447.; https://doi.org/10.1016/j.fct.2010.06.007Test; https://www.sciencedirect.com/science/article/pii/S0278691510003819Test; http://hdl.handle.net/11452/23626Test; 000280991100064; 2-s2.0-77955054088; 2443; 2447; 48; 8-9 |
| DOI: | 10.1016/j.fct.2010.06.007 |
| الإتاحة: | https://doi.org/10.1016/j.fct.2010.06.007Test http://hdl.handle.net/11452/23626Test https://www.sciencedirect.com/science/article/pii/S0278691510003819Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.34ABA55B |
| قاعدة البيانات: | BASE |
| تدمد: | 02786915 18736351 |
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| DOI: | 10.1016/j.fct.2010.06.007 |