دورية أكاديمية

Desmoplastic neurotropic melanoma: A diagnostic trap

التفاصيل البيبلوغرافية
العنوان: Desmoplastic neurotropic melanoma: A diagnostic trap
المؤلفون: Arpaci, Rabia Bozdogan, Kara, Tuba, Serinsoz, Ebru, Karabulut, Yasemin Yuyucu, Gursoy, Didar, Sari, Alper, Ozgur, Anil, Arpaci, Taner
بيانات النشر: DERI ZUHREVI HASTALIKLAR DERNEGI
سنة النشر: 2015
المجموعة: Acibadem University Repository
مصطلحات موضوعية: Diagnostics, head and neck tumors, melanoma
الوصف: Desmoplastic neurotropic melanoma (DNM) is known as a rare variant of cutaneous melanoma. The authors defined the term `neurotropic' which is used to refer to the associated nerve infiltration or neural differentiation. A 74-year-old female applied to the plastic surgery clinic with a one-year history of a nodule in the left infraorbital skin. The lesion was excised by the surgeons and was sent to the pathology department. The tumor with spindle cells in a scar-like stroma was detected microscopically and diagnosed as a `dermatofibroma'. Eight months after surgery, a deep-seated nodule recurred at the same place. This nodule was re-excised. In this sample, we observed hypercellularity, atypical mitoses and nerve infiltration of the spindle tumor cells having strong positive staining with S-100 protein and negative staining with HMB-45, thus, the ultimate diagnosis was DNM. The differential diagnosis of this lesion includes many benign and malignant entities. This is crucial because of the potential for recurrence and metastasis of the lesion. ; 2 ; 153-156 ; 49
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
العلاقة: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY; https://hdl.handle.net/11443/1526Test; http://dx.doi.org/10.4274/turkderm.75350Test; WOS:000369627900014
DOI: 10.4274/turkderm.75350
الإتاحة: https://doi.org/10.4274/turkderm.75350Test
https://hdl.handle.net/11443/1526Test
رقم الانضمام: edsbas.610CE989
قاعدة البيانات: BASE