دورية أكاديمية

Oxidative stress induced sperm DNA damage, a possible reason for male infertility

التفاصيل البيبلوغرافية
العنوان: Oxidative stress induced sperm DNA damage, a possible reason for male infertility
المؤلفون: Md Bayejid Hosen, Md Rakibul Islam, Firoza Begum, Yearul Kabir, Zakir Hossain Howlader
المصدر: Iranian Journal of Reproductive Medicine, Vol 13, Iss 9, Pp 525-532 (2015)
بيانات النشر: Shahid Sadoughi University of Medical Science, Yazd, Iran, 2015.
سنة النشر: 2015
المجموعة: LCC:Gynecology and obstetrics
LCC:Reproduction
مصطلحات موضوعية: DNA damage, Lipid peroxidation, Male infertility, Oxidative stress, Sperm quality., Gynecology and obstetrics, RG1-991, Reproduction, QH471-489
الوصف: Background: Sperm DNA damage is an important factor in the etiology of male infertility. Objective: The aim of the study was to evaluate the association of oxidative stress induced sperm DNA damage with the pathogenesis of male infertility. Materials and Methods: The study comprised a total of 66 subjects, including fertile men (n=25) and infertile men (n=41) matched by age. Seminal malondialdehyde (MDA), phospholipid hydroperoxide (PHP), superoxide dismutase (SOD), total antioxidant status (TAS) and 8-hydroxy-2'-deoxy guanosine (8-OHdG) were estimated by spectrophotometric and ELISA based methods and the association with the sperm parameters was assessed. Results: The percentages of motile and morphologically normal cells were significantly lower (p < 0.001, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1680-6433
2008-2177
العلاقة: http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1644/882Test; https://doaj.org/toc/1680-6433Test; https://doaj.org/toc/2008-2177Test
الوصول الحر: https://doaj.org/article/d7c6d955ebea4a17977481b5c8917a75Test
رقم الانضمام: edsdoj.7c6d955ebea4a17977481b5c8917a75
قاعدة البيانات: Directory of Open Access Journals