دورية أكاديمية
Oxidative stress induced sperm DNA damage, a possible reason for male infertility
العنوان: | Oxidative stress induced sperm DNA damage, a possible reason for male infertility |
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المؤلفون: | Md Bayejid Hosen, Md Rakibul Islam, Firoza Begum, Yearul Kabir, Zakir Hossain Howlader |
المصدر: | Iranian Journal of Reproductive Medicine, Vol 13, Iss 9, Pp 525-532 (2015) |
بيانات النشر: | Shahid Sadoughi University of Medical Science, Yazd, Iran, 2015. |
سنة النشر: | 2015 |
المجموعة: | LCC:Gynecology and obstetrics LCC:Reproduction |
مصطلحات موضوعية: | DNA damage, Lipid peroxidation, Male infertility, Oxidative stress, Sperm quality., Gynecology and obstetrics, RG1-991, Reproduction, QH471-489 |
الوصف: | Background: Sperm DNA damage is an important factor in the etiology of male infertility. Objective: The aim of the study was to evaluate the association of oxidative stress induced sperm DNA damage with the pathogenesis of male infertility. Materials and Methods: The study comprised a total of 66 subjects, including fertile men (n=25) and infertile men (n=41) matched by age. Seminal malondialdehyde (MDA), phospholipid hydroperoxide (PHP), superoxide dismutase (SOD), total antioxidant status (TAS) and 8-hydroxy-2'-deoxy guanosine (8-OHdG) were estimated by spectrophotometric and ELISA based methods and the association with the sperm parameters was assessed. Results: The percentages of motile and morphologically normal cells were significantly lower (p < 0.001, p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1680-6433 2008-2177 |
العلاقة: | http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1644/882Test; https://doaj.org/toc/1680-6433Test; https://doaj.org/toc/2008-2177Test |
الوصول الحر: | https://doaj.org/article/d7c6d955ebea4a17977481b5c8917a75Test |
رقم الانضمام: | edsdoj.7c6d955ebea4a17977481b5c8917a75 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16806433 20082177 |
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