Fear of hypoglycaemia and its relation to hypoglycaemia awareness and symptom intensity in Type 1 diabetes

التفاصيل البيبلوغرافية
العنوان: Fear of hypoglycaemia and its relation to hypoglycaemia awareness and symptom intensity in Type 1 diabetes
المؤلفون: Sandra Elise Olsen, Håvard Hatle, Marit R. Bjørgaas, Torstein Baade Rø, Bjørn Olav Åsvold
المصدر: Diabetes Research and Clinical Practice
بيانات النشر: Elsevier, 2018.
سنة النشر: 2018
مصطلحات موضوعية: Adult, Male, Pediatrics, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, 030209 endocrinology & metabolism, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Surveys and Questionnaires, Diabetes mellitus, Internal Medicine, medicine, Humans, 030212 general & internal medicine, Symptom intensity, media_common, Type 1 diabetes, Multivariable linear regression, business.industry, nutritional and metabolic diseases, Fear, General Medicine, Awareness, Middle Aged, medicine.disease, Hypoglycemia, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Female, Hypoglycaemia awareness, Worry, business, Symptom score, hormones, hormone substitutes, and hormone antagonists
الوصف: Aims To investigate fear of hypoglycaemia (FoH) in relation to hypoglycaemia awareness, history of severe hypoglycaemia (SH) and hypoglycaemia symptoms in adults with Type 1 diabetes. Methods Questionnaire-based cross-sectional survey. We assessed FoH with the Hypoglycaemia Fear Survey-II Worry subscale, hypoglycaemia awareness status with the Gold score, and used the Edinburgh Hypoglycaemia Scale to grade the presence and intensity of hypoglycaemia symptoms. All these measures have previously been validated for research application. We used multivariable linear regression to examine associations between FoH and hypoglycaemia awareness status, history of SH and hypoglycaemia symptom score. Results Of 636 invitees, 445 (70%) responded, with 435 responses eligible for analyses. Seventy-four persons had IAH (17%). Among those, 47 (64%) reported ≥ 1 SH during the preceding year, in contrast to this being reported by 113 (31%) of persons with normal awareness. The mean (SD) FoH worry score was 1.33 (0.78). This score was 0.64 (95% CI, 0.45–0.83) higher among people with impaired vs. normal hypoglycaemia awareness and 0.53 (95% CI, 0.33–0.73) higher among people with ≥ 3 episodes of SH the preceding year vs. people with no such episode. A higher number and intensity of hypoglycaemia symptoms was associated with higher FoH, as demonstrated by an increase in mean FoH worry score of 0.30 (95% CI, 0.23–0.36) per point increase in mean Edinburgh hypoglycaemia score. Conclusions Impaired awareness of hypoglycaemia, history of SH and higher Edinburgh hypoglycaemia scores were all associated with increased FoH in adults with Type 1 diabetes. © 2018. This is the authors’ accepted and refereed manuscript to the article. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0Test/
اللغة: English
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec9e2ac6571e4252b6354eeb6322e5bTest
http://hdl.handle.net/11250/2587387Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....fec9e2ac6571e4252b6354eeb6322e5b
قاعدة البيانات: OpenAIRE