دورية أكاديمية

Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia

التفاصيل البيبلوغرافية
العنوان: Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia
المؤلفون: Pierre Hirsch, Yanyan Zhang, Ruoping Tang, Virginie Joulin, Hélène Boutroux, Elodie Pronier, Hannah Moatti, Pascale Flandrin, Christophe Marzac, Dominique Bories, Fanny Fava, Hayat Mokrani, Aline Betems, Florence Lorre, Rémi Favier, Frédéric Féger, Mohamad Mohty, Luc Douay, Ollivier Legrand, Chrystèle Bilhou-Nabera, Fawzia Louache, François Delhommeau
المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
بيانات النشر: Nature Portfolio, 2016.
سنة النشر: 2016
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Pre-leukaemic clones, together with the propensity to cause disease in mice, are characterized by appearing early in myeloid leukaemia and being found at relapse. Here, the authors identify clones in human samples and find that they are characterized by hierarchically organized genetic lesions, which can be used to track evolution of the disease.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
العلاقة: https://doaj.org/toc/2041-1723Test
DOI: 10.1038/ncomms12475
الوصول الحر: https://doaj.org/article/2dbbe918315649bd816bccb6c1b9c78cTest
رقم الانضمام: edsdoj.2dbbe918315649bd816bccb6c1b9c78c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/ncomms12475