دورية أكاديمية
International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis.
| العنوان: | International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis. |
|---|---|
| المؤلفون: | Chen, Xin, Tsvetkov, Andrey S, Shen, Han-Ming, Isidoro, Ciro, Ktistakis, Nicholas T, Linkermann, Andreas, Koopman, Werner J H, Simon, Hans-Uwe, Galluzzi, Lorenzo, Luo, Shouqing, Xu, Daqian, Gu, Wei, Peulen, Olivier, Cai, Qian, Rubinsztein, David C, Chi, Jen-Tsan, Zhang, Donna D, Li, Changfeng, Toyokuni, Shinya, Liu, Jinbao, Roh, Jong-Lyel, Dai, Enyong, Juhasz, Gabor, Liu, Wei, Zhang, Jianhua, Yang, Minghua, Liu, Jiao, Zhu, Ling-Qiang, Zou, Weiping, Piacentini, Mauro, Ding, Wen-Xing, Yue, Zhenyu, Xie, Yangchun, Petersen, Morten, Gewirtz, David A, Mandell, Michael A, Chu, Charleen T, Sinha, Debasish, Eftekharpour, Eftekhar, Zhivotovsky, Boris, Besteiro, Sébastien, Gabrilovich, Dmitry I, Kim, Do-Hyung, Kagan, Valerian E, Bayir, Hülya, Chen, Guang-Chao, Ayton, Scott, Lünemann, Jan D, Komatsu, Masaaki, Krautwald, Stefan, Loos, Ben, Baehrecke, Eric H, Wang, Jiayi, Lane, Jon D, Sadoshima, Junichi, Yang, Wan Seok, Gao, Minghui, Münz, Christian, Thumm, Michael, Kampmann, Martin, Yu, Di, Lipinski, Marta M, Jones, Jace W, Jiang, Xuejun, Zeh, Herbert J, Kang, Rui, Klionsky, Daniel J, Kroemer, Guido, Tang, Daolin |
| المصدر: | Autophagy (2024-03-05) |
| بيانات النشر: | Landes Bioscience, 2024. |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Cell death, ferritinophagy, iron, lipid peroxidation, lipophagy, lysosome, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire |
| الوصف: | Macroautophagy/autophagy is a complex degradation process with a dual role in cell death that is influenced by the cell types that are involved and the stressors they are exposed to. Ferroptosis is an iron-dependent oxidative form of cell death characterized by unrestricted lipid peroxidation in the context of heterogeneous and plastic mechanisms. Recent studies have shed light on the involvement of specific types of autophagy (e.g. ferritinophagy, lipophagy, and clockophagy) in initiating or executing ferroptotic cell death through the selective degradation of anti-injury proteins or organelles. Conversely, other forms of selective autophagy (e.g. reticulophagy and lysophagy) enhance the cellular defense against ferroptotic damage. Dysregulated autophagy-dependent ferroptosis has implications for a diverse range of pathological conditions. This review aims to present an updated definition of autophagy-dependent ferroptosis, discuss influential substrates and receptors, outline experimental methods, and propose guidelines for interpreting the results. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article peer reviewed |
| اللغة: | English |
| العلاقة: | urn:issn:1554-8627; urn:issn:1554-8635 |
| DOI: | 10.1080/15548627.2024.2319901 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/314154Test |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2Test info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.314154 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1080/15548627.2024.2319901 |
|---|