المؤلفون: Ebekozien, Osagie, Mungmode, Ann, Sanchez, Janine, Rompicherla, Saketh, Demeterco-Berggren, Carla, Weinstock, Ruth S., Jacobsen, Laura M., Davis, Georgia, McKee, Alexis, Akturk, Halis K., Maahs, David M., Kamboj, Manmohan K.

المصدر: Diabetes Technology & Therapeutics; Nov2023, Vol. 25 Issue 11, p765-773, 9p

المؤلفون: Ospelt, Emma, Noor, Nudrat, Sanchez, Janine, Nelson, Grace, Rioles, Nicole, Malik, Faisal S., Basina, Marina, Indyk, Justin, Vendrame, Francesco, Schmitt, Jessica, Scott, Mary L., Ebekozien, Osagie

المصدر: Clinical Diabetes; Winter2023, Vol. 41 Issue 1, p56-67, 12p

مصطلحات موضوعية: ENDOCRINOLOGY, MEDICAL quality control, HEALTH services accessibility, PROFESSIONS, INTERNET, ATTITUDES of medical personnel, STAKEHOLDER analysis, RESEARCH methodology, DRUG administration, INSULIN, DRUG prescribing, QUALITY assurance, INTERPROFESSIONAL relations, RESEARCH funding, HEALTH care teams, PHYSICIAN practice patterns

مصطلحات جغرافية: UNITED States

مستخلص: This study sought to identify barriers and facilitators to successful smart insulin pen (SIP) use and gauge prescribing practices and integration into clinical practice by assessing provider and care team perspectives at participating endocrinology clinics within the T1D Exchange Quality Improvement Collaborative. The identified provider-related, patient-related, and clinic- and operational-level barriers and facilitators varied based on clinic knowledge, capacity, and resources. High-impact barriers included insurance coverage and prescribing processes; high-impact facilitators included improved diabetes clinic visit quality and use of SIPs as an alternative to insulin pump therapy. Findings indicated the need for provider and care team education and training on proper SIP features, use, and prescribing. [ABSTRACT FROM AUTHOR]

: Copyright of Clinical Diabetes is the property of American Diabetes Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Brodar, Kaitlyn E., Hong, Natalie, Liddle, Melissa, Hernandez, Lisandra, Waks, Judy, Sanchez, Janine, Delamater, Alan, Davis, Eileen

المصدر: Journal of Clinical Psychology in Medical Settings; Dec2022, Vol. 29 Issue 4, p727-738, 12p

مصطلحات موضوعية: NURSE liaisons, DIABETES in children, PEDIATRIC clinics, TELEMEDICINE, INTERDISCIPLINARY communication, ELECTRONIC health records

الشركة/الكيان: PEOPLE'S Dispensary for Sick Animals

مستخلص: COVID-19 necessitated a rapid shift to telehealth for psychologists offering consultation-liaison services in pediatric medical settings. However, little is known about how psychologists providing these services adapted to using telehealth service delivery formats. This report details how our interdisciplinary team identified declining psychosocial screener completion and psychology consultation rates as primary challenges following a shift to telehealth within a pediatric diabetes clinic. We utilized the Plan-Do-Study-Act (PDSA) quality improvement framework to improve screening and consultation rates, which initially declined during the telehealth transition. Screening and consultation rates dropped initially, but recovered to nearly pre-pandemic levels following three PDSA intervention cycles. During implementation, challenges arose related to the feasibility of patient interactions, interdisciplinary collaboration, patient engagement, and ethical issues. Clinics shifting psychology consultation-liaison services to telehealth should prioritize interdisciplinary communication, elicit perspectives from all clinic professionals, leverage the electronic health record, and develop procedures for warm handoffs and navigating ethical issues. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Clinical Psychology in Medical Settings is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Zimmerman, Chelsea F., Bowater, Katelin L., Revels, Maureen R., Sanchez, Janine E., Gordon, Victoria I., Adams, Janey G., Oyetoro, Rebecca O., Albanese-O'Neill, Anastasia

المصدر: Journal of Pediatric Nursing; Nov2022, Vol. 67, p77-82, 6p

مستخلص: Children with diabetes spend a significant portion of time at school and in school-related activities and rely on school nurses for diabetes management support. Diabetes technologies are rapidly evolving, and there are no standardized competencies or training programs for school personnel providing diabetes care. A virtual diabetes education program was provided to school nurses and staff in 3 Florida school districts. Program feasibility was measured by attendance; acceptability was measured with a usability survey; and efficacy was measured by participants' improvements in scores on pre- and post-training knowledge assessments. Descriptive statistics were generated and improvements in knowledge were evaluated via t -test. P -values <0.05 were considered significant. Pilot survey data (n = 91) revealed high demand for diabetes technology and basic management education among school nurses and staff. Eighty-eight school personnel from 64 schools attended the training, with 67 participants completing the demographic survey and at least one of the pre- and post-training assessments. Post-test scores demonstrated mean + 10.6% absolute improvement on the diabetes technology subscale, +11.5% on the basic management subscale, and + 10.9% on the ketone management subscale, all p < 0.001. Fifty-three participants completed the usability survey with 92% reporting they benefitted from training. Virtual training is feasible and acceptable for delivering diabetes technology education to large numbers of school personnel. Study results demonstrate improved diabetes knowledge. Establishing a standardized training program on diabetes technology for school personnel can optimize diabetes care in the school setting. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Pediatric Nursing is the property of W B Saunders and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Brodar, Kaitlyn E., Leite, Rafael O., Jaramillo, Manuela, Marchetti, Daniella, Davis, Eileen, Sanchez, Janine, Saab, Patrice G., Delamater, Alan M., La Greca, Annette M.

المصدر: Pediatric Diabetes; Nov2022, Vol. 23 Issue 7, p1101-1112, 12p

مصطلحات موضوعية: CAREGIVER attitudes, AFFINITY groups, SOCIAL support, PSYCHOLOGY of mothers, RESEARCH methodology, MEDICAL screening, TYPE 1 diabetes, INTERVIEWING, QUALITATIVE research, PSYCHOSOCIAL factors, DESCRIPTIVE statistics, THEMATIC analysis, CONTENT analysis, PEOPLE with diabetes, ADOLESCENCE

مصطلحات جغرافية: FLORIDA

مستخلص: Objective: Adolescents with type 1 diabetes (T1D) frequently experience psychosocial concerns, and mental health screening is becoming increasingly common in routine diabetes care. However, little is known about what adolescents or their caregivers think about the role of mental health screening and intervention within the context of comprehensive diabetes care, or how their diabetes care providers should be involved in navigating mental health concerns. This study used qualitative methods to obtain the perspectives of adolescents with T1D and their caregivers regarding these issues. Methods: Participants were 13 adolescents with T1D (ages 12–19 years; M = 15.1 years; 53.8% female; 61.5% Hispanic/Latinx White) and 13 mothers, recruited from an outpatient pediatric endocrinology clinic in South Florida, who participated in semi‐structured interviews via video teleconference. Thematic content analysis was used to evaluate participants' responses. Results: Adolescents and their mothers reported positive experiences with the clinic's psychosocial screening procedures and appreciated meeting with the psychology team during visits. They wanted the clinic to offer more opportunities for peer support. Mothers highlighted barriers to seeking mental health care outside of the clinic and the importance of mental health professionals understanding diabetes. Mothers also wanted the clinic to offer more on‐site therapeutic services. Discussion: Study participants valued psychosocial screening and supported addressing mental health as a routine part of diabetes comprehensive care. [ABSTRACT FROM AUTHOR]

: Copyright of Pediatric Diabetes is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Malik, Jamil A, Coto, Jennifer, Pulgaron, Elizabeth R, Daigre, Amber, Sanchez, Janine E, Goldberg, Ronald B, Wilson, Dawn K, Delamater, Alan M

المصدر: Translational Behavioral Medicine; Aug2021, Vol. 11 Issue 8, p1517-1526, 10p

مستخلص: This study investigated the role of objectively measured moderate–vigorous physical activity (MVPA) and sedentary behavior on cardiometabolic risk factors of young Latino children. We hypothesized that MVPA would be associated with lower cardiometabolic risk when sedentary behavior is low. We studied 86 primarily low-income, Latino children using a cross-sectional study design. The study sample consisted of 51 girls and 35 boys, with mean age 5.6 (SD =.53) years. Physical activity was measured by accelerometry, anthropometric measures obtained, and fasting blood samples were used to measure cardiometabolic risk factors. Greater levels of sedentary behavior were associated with increased waist circumference (r s =.24, p <.05) and metabolic risks. MVPA, however, had significant beneficial associations with all cardiometabolic risk factors (r s-range = −.20 to −.45, p <.05) with the exception of plasma insulin. MVPA predicted latent variables representing anthropometric risk (β = −.57, p <.01), cardiac risk (β = −.74, p <.01), and metabolic risk (β = −.88, p <.01). Sedentary behavior significantly moderated the effect of MVPA on anthropometric (β -interaction =.49, p <.01), cardiac (β -interaction =.45, p <.01), and metabolic risk (β -interaction =.77, p <.01), such that more MVPA was associated with better health outcomes under conditions of lower sedentary behavior. The model explained 13%, 22%, and 45% variance in anthropometric, cardiac, and metabolic risk factors, respectively. Increased MVPA is associated with decreased cardiometabolic risk in young Latino children, particularly when sedentary behavior is low. This study investigated the role of objectively measured moderate-vigorous physical activity (MVPA) and sedentary behavior on cardiometabolic risk factors of young Latino children. We found that sedentary behavior significantly moderated the effect of MVPA on cardiometabolic risk, such that more MVPA was associated with better health outcomes under conditions of lower sedentary behavior. [ABSTRACT FROM AUTHOR]

: Copyright of Translational Behavioral Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Alonso, Guy Todd, Ebekozien, Osagie, Gallagher, Mary Pat, Rompicherla, Saketh, Lyons, Sarah K., Choudhary, Abha, Majidi, Shideh, Pinnaro, Catherina T., Balachandar, Sadana, Gangat, Mariam, Curda Roberts, Alissa Jeanne, Marks, Brynn E., Creo, Ana, Sanchez, Janine, Seeherunvong, Tossaporn, Jimenez‐Vega, Jose, Patel, Neha S., Wood, Jamie R., Gabriel, Liana, Sumpter, Kathryn M.

المصدر: Journal of Diabetes; Aug2021, Vol. 13 Issue 8, p681-687, 7p

مصطلحات موضوعية: TYPE 1 diabetes, COVID-19, DIABETIC acidosis, FISHER exact test, CHILD patients

الملخص (بالإنجليزية): Background: Diabetes is a risk factor for poor COVID‐19 outcomes, but pediatric patients with type 1 diabetes are poorly represented in current studies. Methods: T1D Exchange coordinated a US type 1 diabetes COVID‐19 registry. Forty‐six diabetes centers submitted pediatric cases for patients with laboratory confirmed COVID‐19. Associations between clinical factors and hospitalization were tested with Fisher's Exact Test. Logistic regression was used to calculate odds ratios for hospitalization. Results: Data from 266 patients with previously established type 1 diabetes aged <19 years with COVID‐19 were reported. Diabetic ketoacidosis (DKA) was the most common adverse outcome (n = 44, 72% of hospitalized patients). There were four hospitalizations for severe hypoglycemia, three hospitalizations requiring respiratory support (one of whom was intubated and mechanically ventilated), one case of multisystem inflammatory syndrome in children, and 10 patients who were hospitalized for reasons unrelated to COVID‐19 or diabetes. Hospitalized patients (n = 61) were more likely than nonhospitalized patients (n = 205) to have minority race/ethnicity (67% vs 39%, P < 0.001), public insurance (64% vs 41%, P < 0.001), higher A1c (11% [97 mmol/mol] vs 8.2% [66 mmol/mol], P < 0.001), and lower insulin pump and lower continuous glucose monitoring use (26% vs 54%, P < 0.001; 39% vs 75%, P < 0.001). Age and gender were not associated with risk of hospitalization. Higher A1c was significantly associated with hospitalization, with an odds ratio of 1.56 (1.34‐1.84) after adjusting for age, gender, insurance, and race/ethnicity. Conclusions: Higher A1c remained the only predictor for hospitalization with COVID‐19. Diabetic ketoacidosis is the primary concern among this group. [ABSTRACT FROM AUTHOR]

Abstract (Chinese): 摘要 背景: 糖尿病是新型冠状病毒肺炎预后差的危险因素, 但在目前的研究中, 1型糖尿病儿童患者的情况鲜有报道。 方法: T1D交流处协调了一个美国新型冠状病毒肺炎1型糖尿病的临床注册研究。46个糖尿病中心提交了实验室确认的新型冠状病毒肺炎患者的儿童病例。采用Fisher's 确切检验分析临床因素与住院时间的相关性。用Logistic回归计算住院的优势比。 结果: 报道了266例既往确诊的<19岁的1型糖尿病患者患有新型冠状病毒肺炎的资料。糖尿病酮症酸中毒(DKA)是最常见的不良结局(n=44, 72%的住院患者)。因严重低血糖住院4例, 需要呼吸支持住院3例(其中1例经气管插管机械通气), 1例儿童多系统炎症综合征, 10例因与新型冠状病毒肺炎或糖尿病无关的原因住院。住院患者(n=61)与非住院患者(n=205)相比:少数族裔占比更高(67%比39%, P<0.001)、公共保险覆盖率更高(64%比41%, P<0.001)、糖化血红蛋白更高(11%[97 mmol/mol]比8.2%[66 mmol/mol], P<0.001)、胰岛素泵以及连续血糖监测系统使用率更低(26%比54%, P<0.001, 39%比75%, P<0.001)。年龄和性别与住院风险无关。较高的糖化血红蛋白与住院显著相关, 在校正了年龄、性别、保险和种族后, 优势比为1.56(1.34‐1.84)。 结论: 较高的糖化血红蛋白仍然是新型冠状病毒肺炎住院的唯一预测因素。糖尿病酮症酸中毒是这一群体的首要问题。 [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Diabetes is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Brodar, Kaitlyn E., Davis, Eileen M., Lynn, Courtney, Starr‐Glass, Lolly, Lui, Joyce H. L., Sanchez, Janine, Delamater, Alan M.

المصدر: Pediatric Diabetes; Jun2021, Vol. 22 Issue 4, p656-666, 11p

مصطلحات موضوعية: DIAGNOSIS of eating disorders, PSYCHIATRIC diagnosis, INSULIN therapy, SUICIDE risk factors, GLYCOSYLATED hemoglobin, ACADEMIC medical centers, EVALUATION of human services programs, GLYCEMIC control, MOTIVATION (Psychology), BLOOD sugar monitoring, TYPE 1 diabetes, MEDICAL screening, PEDIATRICS, REGRESSION analysis, FAMILY conflict, PSYCHOSOCIAL factors, DRUGS, DESCRIPTIVE statistics, MENTAL depression, MEDICAL referrals, PATIENT compliance, ANXIETY, PEOPLE with diabetes, PSYCHOLOGICAL stress, ADOLESCENCE

مستخلص: Objective: The ISPAD recommends routine, comprehensive psychosocial screening for adolescents with diabetes. However, few clinics have implemented procedures consistent with these guidelines. This study describes the results of a universal, comprehensive psychosocial screening program in an integrated pediatric diabetes clinic located within an academic medical center. Research Design and Methods: Participants included 232 ethnically diverse adolescents with type 1 diabetes (55.5% female; M age = 14.85; 58.5% Hispanic; 20% Black). Adolescents completed screening measures on iPads in the waiting room before their medical visit. The proportion of adolescents screening positive on each psychosocial measure was assessed, and regression analyses evaluated how psychosocial variables accounted for variance in insulin non‐adherence and glycemic control (measured by A1c). Results: Psychosocial concerns were common and ranged from 7% of adolescents screening positive for disordered eating and suicide risk to 52% screening positive for low motivation to manage diabetes. A1c and insulin non‐adherence were positively correlated with suicide risk, depressive symptoms, anxiety, disordered eating, diabetes stress, blood glucose monitoring stress, family conflict, and total number of elevations, and negatively correlated with intrinsic motivation. Insulin non‐adherence, disordered eating, diabetes stress, and family conflict uniquely predicted A1c. Age, motivation, and family conflict uniquely predicted insulin non‐adherence. Eighty‐three percent of eligible youth completed the screener. Referrals by physicians to the team psychologist increased by 25% after the screening program was implemented. Conclusions: Comprehensive psychosocial screening can be effectively implemented as part of routine pediatric diabetes care and can identify adolescents in need of additional supports. [ABSTRACT FROM AUTHOR]

: Copyright of Pediatric Diabetes is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Ebekozien, Osagie, Agarwal, Shivani, Noor, Nudrat, Albanese-O'Neill, Anastasia, Wong, Jenise C., Seeherunvong, Tossaporn, Sanchez, Janine, DeSalvo, Daniel, Lyons, Sarah K., Majidi, Shideh, Wood, Jamie R., Acharya, Runa, Aleppo, Grazia, Sumpter, Kathryn M., Cymbaluk, Anna, Shah, Nirali A., Van Name, Michelle, Cruz-Aviles, Lisa, Alonso, Guy Todd, Gallagher, Mary Pat

المصدر: Journal of Clinical Endocrinology & Metabolism; Apr2021, Vol. 106 Issue 4, pe1755-e1762, 8p

مصطلحات موضوعية: TYPE 1 diabetes, DIABETIC acidosis, COVID-19, KETOACIDOSIS

مستخلص: Objective: We examined whether diabetic ketoacidosis (DKA), a serious complication of type 1 diabetes (T1D) was more prevalent among Non-Hispanic (NH) Black and Hispanic patients with T1D and laboratory-confirmed coronavirus disease 2019 (COVID-19) compared with NH Whites.Method: This is a cross-sectional study of patients with T1D and laboratory-confirmed COVID-19 from 52 clinical sites in the United States, data were collected from April to August 2020. We examined the distribution of patient factors and DKA events across NH White, NH Black, and Hispanic race/ethnicity groups. Multivariable logistic regression analysis was performed to examine the odds of DKA among NH Black and Hispanic patients with T1D as compared with NH White patients, adjusting for potential confounders, such as age, sex, insurance, and last glycated hemoglobin A1c (HbA1c) level.Results: We included 180 patients with T1D and laboratory-confirmed COVID-19 in the analysis. Forty-four percent (n = 79) were NH White, 31% (n = 55) NH Black, 26% (n = 46) Hispanic. NH Blacks and Hispanics had higher median HbA1c than Whites (%-points [IQR]: 11.7 [4.7], P < 0.001, and 9.7 [3.1] vs 8.3 [2.4], P = 0.01, respectively). We found that more NH Black and Hispanic presented with DKA compared to Whites (55% and 33% vs 13%, P < 0.001 and P = 0.008, respectively). After adjusting for potential confounders, NH Black patients continued to have greater odds of presenting with DKA compared with NH Whites (OR [95% CI]: 3.7 [1.4, 10.6]).Conclusion: We found that among T1D patients with COVID-19 infection, NH Black patients were more likely to present in DKA compared with NH White patients. Our findings demonstrate additional risk among NH Black patients with T1D and COVID-19. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Clinical Endocrinology & Metabolism is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Bowman, Pamela, Mathews, Frances, Barbetti, Fabrizio, Shepherd, Maggie H., Sanchez, Janine, Piccini, Barbara, Beltrand, Jacques, Letourneau-Freiberg, Lisa R., Polak, Michel, Greeley, Siri Atma W., Rawlins, Eamon, Babiker, Tarig, Thomas, Nicholas J., De Franco, Elisa, Ellard, Sian, Flanagan, Sarah E., Hattersley, Andrew T., Mohsin, Fauzia, Cummings, Elizabeth, LeGault, Laurent

المصدر: Diabetes Care; Jan2021, Vol. 44 Issue 1, p35-42, 8p

مصطلحات موضوعية: METABOLIC regulation, GLYCEMIC control, ATTENTION-deficit hyperactivity disorder, NEURODEVELOPMENTAL treatment, DIABETES, RESEARCH, GENETIC mutation, RESEARCH methodology, POTASSIUM, HYPOGLYCEMIC agents, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, RESEARCH funding, LONGITUDINAL method

مصطلحات جغرافية: ITALY

مستخلص: Objective: ABCC8 mutations cause neonatal diabetes mellitus that can be transient (TNDM) or, less commonly, permanent (PNDM); ∼90% of individuals can be treated with oral sulfonylureas instead of insulin. Previous studies suggested that people with ABCC8-PNDM require lower sulfonylurea doses and have milder neurological features than those with KCNJ11-PNDM. However, these studies were short-term and included combinations of ABCC8-PNDM and ABCC8-TNDM. We aimed to assess the long-term glycemic and neurological outcomes in sulfonylurea-treated ABCC8-PNDM.Research Design and Methods: We studied all 24 individuals with ABCC8-PNDM diagnosed in the U.K., Italy, France, and U.S. known to transfer from insulin to sulfonylureas before May 2010. Data on glycemic control, sulfonylurea dose, adverse effects including hypoglycemia, and neurological features were analyzed using nonparametric statistical methods.Results: Long-term data were obtained for 21 of 24 individuals (median follow-up 10.0 [range 4.1-13.2] years). Eighteen of 21 remained on sulfonylureas without insulin at the most recent follow-up. Glycemic control improved on sulfonylureas (presulfonylurea vs. 1-year posttransfer HbA1c 7.2% vs. 5.7%, P = 0.0004) and remained excellent long-term (1-year vs. 10-year HbA1c 5.7% vs. 6.5%, P = 0.04), n = 16. Relatively high doses were used (1-year vs. 10-year dose 0.37 vs. 0.25 mg/kg/day glyburide, P = 0.50) without any severe hypoglycemia. Neurological features were reported in 13 of 21 individuals; these improved following sulfonylurea transfer in 7 of 13. The most common features were learning difficulties (52%), developmental delay (48%), and attention deficit hyperactivity disorder (38%).Conclusions: Sulfonylurea treatment of ABCC8-PNDM results in excellent long-term glycemic control. Overt neurological features frequently occur and may improve with sulfonylureas, supporting early, rapid genetic testing to guide appropriate treatment and neurodevelopmental assessment. [ABSTRACT FROM AUTHOR]

: Copyright of Diabetes Care is the property of American Diabetes Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)