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1دورية أكاديمية
المؤلفون: Shalini Gainder, Parul Arora, Lakhbir Kaur Dhaliwal
المصدر: Journal of Human Reproductive Sciences, Vol 11, Iss 3, Pp 286-290 (2018)
مصطلحات موضوعية: Fetal bone, hysteroscopy, operative, secondary infertility, Gynecology and obstetrics, RG1-991
الوصف: Background: Midtrimester surgical abortions often result in retained intrauterine fetal bones and consequent secondary infertility. Aim: To study the incidence of women presenting with retained intrauterine bones as a cause of secondary infertility in a tertiary level Indian hospital and pregnancy rates following retrieval of these fragments. Setting and Design: Retrospective data analysis in the infertility clinic of PGIMER (Post Graduate Institute of Medical Education and Research), a tertiary level hospital of Northern India. Materials and Methods: Women diagnosed with retained intrauterine bony fragments were subjected to hysteroscopic removal of these fragments. Incidentally diagnosed retained bones on hysteroscopy were also removed. Such women were followed for spontaneous resumption of fertility or were subjected to ovulation induction, and pregnancy rates were noted. Results: Retained fetal bones accounted for 0.28% of all women with infertility and 12% (22/144) of all the uterine causes of infertility requiring an operative hysteroscopic procedure for treatment. Only 5 (27.7%) of 18 women conceived after the hysteroscopic retrieval of bony fragments: three had full-term vaginal deliveries, one had a midtrimester abortion, and one woman is in her third trimester. Conclusion: Despite surgical retrieval, fertility rates may be lower due to inflammatory damage to the endometrium.
وصف الملف: electronic resource
العلاقة: http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2018;volume=11;issue=3;spage=286;epage=290;aulast=GainderTest; https://doaj.org/toc/0974-1208Test; https://doaj.org/toc/1998-4766Test
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2دورية أكاديمية
المؤلفون: Lakhbir Kaur Dhaliwal, Vanita Suri, Kamla Rani Gupta, Sumitu Sahdev
المصدر: Journal of Human Reproductive Sciences, Vol 4, Iss 2, Pp 76-79 (2011)
مصطلحات موضوعية: Anovulation, clomiphene, induction of ovulation, polycystic ovary syndrome, tamoxifen, Gynecology and obstetrics, RG1-991
الوصف: Background : Clomiphene citrate is commonly used for ovulation induction in women with anovulatory infertility. However, pregnancy rates with this drug are not as good as ovulation rates. Tamoxifen may be a better choice in some patients who fail to either ovulate or conceive with clomiphene due to its favorable effect on the cervical mucus and endometrium. This study was conducted to evaluate the role of tamoxifen in women with anovulatory infertility and find out the optimum dose needed for achieving the best outcome. Materials and Methods : 160 women attending the infertility clinic and suffering from anovulatory infertility were recruited for the study. Tamoxifen was administered in the dose of 40 mg daily and ovulation monitored. In case of anovulation, the dose was increased to 80 mg daily. Ovulation and pregnancy rates were calculated. Results : Twenty-three out of 160 women who received 40 mg of tamoxifen conceived, giving a pregnancy rate of 14.38% and pregnancy rate per ovulatory cycle as 14.94%. 32 out of 80 women who received 80 mg of tamoxifen conceived, giving a pregnancy rate of 40% and pregnancy rate per cycle as 33.68%. This difference in the pregnancy rate between the two groups was statistically significant. 35 women out of 90 with polycystic ovary syndrome (PCOS) became pregnant with a pregnancy rate of 38.8% and 20 out of 70 women with clomiphene citrate failure conceived, giving a pregnancy rate of 28.5%. Conclusions : Tamoxifen is a good alternative to clomiphene in women with PCOS and clomiphene-resistant cases.
وصف الملف: electronic resource
العلاقة: http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2011;volume=4;issue=2;spage=76;epage=79;aulastTest=Dhaliwal; https://doaj.org/toc/0974-1208Test; https://doaj.org/toc/1998-4766Test
النص الكامل