التفاصيل البيبلوغرافية
| العنوان: |
The role of the human papillomavirus (HPV) vaccine in developing countries. |
| المؤلفون: |
Kling, Max1, Zeichner, Joshua A.1 joshua.zeichner@mssm.edu |
| المصدر: |
International Journal of Dermatology. Apr2010, Vol. 49 Issue 4, p377-379. 3p. 3 Charts. |
| مصطلحات موضوعية: |
*PAPILLOMAVIRUS diseases, *CANCER in women, *CERVICAL cancer, *HUMAN papillomavirus vaccines, *PREVENTIVE medicine, DEVELOPING countries |
| مستخلص: |
Cervical cancer is a preventable health problem, yet is the second most common cancer of women worldwide. More than 80% of cases occur in developing countries, and this is expected to increase to 90% by the year 2020. The five-year survival rate of patients in developing countries is less than 50%, compared to 66% in developed nations. A worldwide HPV vaccine program would significantly reduce the spread of HPV 16 and 18 and lower the incidence of cervical cancer. Mathematical models have determined that vaccinating 66% of the population will decrease the incidence of cervical cancer by 80% over the next 40–60 years. For every five-year delay in a cervical cancer prevention/detection program, there will be an additional 1.5–2.0 million deaths. The introduction of a vaccination program will be a challenge due to high costs, unknown durability of the vaccine, and the potential for new oncogenic strains to emerge. A global effort will be required to eliminate cervical cancer from developing counties. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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