التفاصيل البيبلوغرافية
| العنوان: |
Progressive multifocal leukoencephalopathy in patients with chronic liver disease successfully treated with pembrolizumab. |
| المؤلفون: |
Jeantin, Lina, Shor, Natalia, Coustans, Marc, Roos-Weil, Damien, Quintin-Roué, Isabelle, Bellanger, Agnès, Le Garff-Tavernier, Magali, Ben Jemaa, Rahma, Thabut, Dominique, Pourcher, Valérie, Weiss, Nicolas |
| المصدر: |
Journal of Neurology; Apr2024, Vol. 271 Issue 4, p2119-2124, 6p |
| مصطلحات موضوعية: |
JOHN Cunningham virus, PROGRESSIVE multifocal leukoencephalopathy, CHRONICALLY ill, TREATMENT effectiveness, T-cell exhaustion, PEMBROLIZUMAB |
| مستخلص: |
This document discusses the potential use of pembrolizumab as a treatment for progressive multifocal leukoencephalopathy (PML) in patients with chronic liver disease. PML is a serious infection of the central nervous system typically observed in individuals with severe immunosuppression. The document presents two cases in which PML progression was halted with pembrolizumab treatment, resulting in improvement and regression of PML lesions. The article emphasizes the challenges faced by clinicians in diagnosing and treating PML in patients with liver disease and highlights the need for more evidence to support the use of pembrolizumab in PML treatment. [Extracted from the article] |
|
Copyright of Journal of Neurology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
