التفاصيل البيبلوغرافية
| العنوان: |
A mutation in the general membrane trafficking machinery and hydrocephaly. |
| المصدر: |
Proceedings of the National Academy of Sciences of the United States of America; 2/10/2004, Vol. 101 Issue 6, p1431-1432, 2p |
| مصطلحات موضوعية: |
MEMBRANE fusion, BIOLOGICAL membranes, CELL death, BODY fluids, HYDROCEPHALUS, ORGAN trafficking |
| مستخلص: |
Membrane fusion is required to deliver specific cargo molecules to distinct intracellular compartments, thereby maintaining the functional and structural organization of eukaryotic cells, as well as intercellular communication, which occurs in precisely timed spatial patterns at the plasma membrane. Because membrane trafficking is essential for cell homeostasis and many physiological processes, a complete functional loss of the recycling machinery or most soluble N-ethylmalemide sensitive factor attachment protein receptors leads to cell death or embryonic lethality. |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder