دورية أكاديمية

中药生发液对小鼠脱发的治疗作用研究.

التفاصيل البيبلوغرافية
العنوان: 中药生发液对小鼠脱发的治疗作用研究. (Chinese)
العنوان البديل: Study on therapeutic effect of traditional Chinese medicine hair restorer on hair loss in mice. (English)
المؤلفون: 罗安玲, 陈心馨, 丁运文, 热依沙·吾甫尔, 郑有丽, 丛峰松
المصدر: China Surfactant Detergent & Cosmetics; 2019, Vol. 49 Issue 4, p244-247, 4p
مصطلحات موضوعية: HAIR growth, CHINESE medicine, LACTATE dehydrogenase, HAIR follicles, HAIR removal, BALDNESS
الملخص (بالإنجليزية): The therapeutic effect of traditional Chinese medicine hair restorer on hair loss in mice was studied by applying the hair restorer to the hair removal area on the back mice. The effect of hair restorer on hair regeneration rate was evaluated by measuring the newborn hair length on mice. The effect of hair restorer on the morphology of hair follicles and the terminal/vellus hair ratio was evaluated by observing the skin HE staining section. The effect of hair restorer on collagen fiber arrangement was evaluated by observing the skin Masson staining section. The effect of hair restorer on the expression of lactate dehydrogenase(Ldha)was detected by Western Blot. The results show that compared with the control group, the hair regeneration rate is accelerated, the number of hair follicles increases, the terminal/vellus hair ratio increases, collagen fibers arrange more closely and orderly, and the expression of Ldha is up-regulated in the treatment group, which indicate that the traditional Chinese medicine hair restorer has an efficacy of promoting hair growth. [ABSTRACT FROM AUTHOR]
Abstract (Chinese): 通过给小鼠背部脱毛区涂抹中药生发液,研究了生发液对小鼠脱发的治疗作用。通过测量小鼠新生毛发的长度考 察生发液对毛发再生速度的影响;利用皮肤HE染色切片研究生发液对毛囊形态结构和终毛/毳毛比值的影响;利用皮肤 Masson染色切片研究生发液对胶原纤维排列的影响;利用Western Blot法研究生发液对皮肤内乳酸脱氢酶(Ldha)表达的 影响。结果表明,与对照组比较,经中药生发液处理后的药物组毛发再生速度加快、毛囊数量增多、终毛/毳毛比值提 高、胶原纤维排列更紧密有序、Ldha表达上调,说明中药生发液具有促进毛发生长的功效. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:10011803
DOI:10.3969/j.issn.1001-1803.2019.04.008