التفاصيل البيبلوغرافية
| العنوان: |
Epidemiology of Mammalian Hepatitis E Virus Infection. |
| المؤلفون: |
Kaba, Mamadou, Moal, Valérie, Gérolami, René, Colson, Philippe |
| المصدر: |
Intervirology; Jan2013, Vol. 56 Issue 2, p67-83, 17p |
| مصطلحات موضوعية: |
EPIDEMIOLOGY, HEPATITIS E, HEPATITIS E virus, MAMMAL diseases, ETIOLOGY of diseases, ELECTRON microscopy, IMMUNOGLOBULIN G, DISEASE prevalence, THERAPEUTICS |
| مستخلص: |
Mammalian hepatitis E virus (HEV), the etiological agent of hepatitis E in humans, is a recently discovered infectious agent. It was identified for the first time in 1983 using elec-tron microscopy on a faecal specimen of a person infected with non-A, non-B enterically-transmitted hepatitis. Based on retrospective and prospective studies, HEV was long de-scribed as one of the leading causes of acute viral hepatitis in tropical and subtropical countries, whereas in developed countries hepatitis E was considered an imported disease from HEV hyperendemic countries. Data from studies con-ducted during the past decade have greatly shifted our knowledge on the epidemiology and clinical spectrum of HEV. Recently, it has been shown that contrary to previous beliefs, hepatitis E is also an endemic disease in several de-veloped countries, particularly in Japan and in Europe, as evidenced by reports of high anti-HEV immunoglobulin G prevalence in healthy individuals and an increasing number of non-travel-related acute hepatitis E cases. Moreover, a porcine reservoir and growing evidence of zoonotic transmission have been reported in these countries. This review summarizes the current knowledge on the epidemiology and prevention of transmission of mammalian HEV. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
