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1دورية أكاديمية
المؤلفون: Zhang, Jia-Yuan, Hamey, Fiona, Trzupek, Dominik, Mickunas, Marius, Lee, Mercede, Godfrey, Leila, Yang, Jennie HM, Pekalski, Marcin L, Kennet, Jane, Waldron-Lynch, Frank, Evans, Mark L, Tree, Timothy IM, Wicker, Linda S, Todd, John A, Ferreira, Ricardo C
المصدر: essn: 2041-1723 ; nlmid: 101528555
مصطلحات موضوعية: Humans, Anti-Inflammatory Agents, Diabetes Mellitus, Type 1, Gene Expression, Interleukin-2, T-Lymphocytes
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.17863/CAM.92343Test
https://www.repository.cam.ac.uk/handle/1810/344918Test -
2دورية أكاديمية
المؤلفون: Lee, Mercede, Bell, Charles J M, Rubio Garcia, Arcadio, Godfrey, Leila, Pekalski, Marcin, Wicker, Linda S, Todd, John A, Ferreira, Ricardo C
المساهمون: Wellcome, Wellcome Trust, Bristol Myers Squibb, NIHR Oxford Biomedical Research Centre
المصدر: Discovery Immunology ; volume 2, issue 1 ; ISSN 2754-2483
الإتاحة: https://doi.org/10.1093/discim/kyad012Test
https://academic.oup.com/discovimmunology/article-pdf/2/1/kyad012/51301612/kyad012.pdfTest -
3تقرير
المؤلفون: Skalic, Miha, Pekalski, Marcin, Pan, Xingguo E.
مصطلحات موضوعية: Statistics - Machine Learning, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Learning
الوصول الحر: http://arxiv.org/abs/1706.04572Test
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4دورية أكاديمية
المؤلفون: Sandholm, Niina, Garcia, Arcadio Rubio, Pekalski, Marcin L., Inshaw, Jamie R. J., Cutler, Antony J., Todd, John A.
المساهمون: Research Programs Unit, Medicum, HUS Abdominal Center, University of Helsinki, CAMM - Research Program for Clinical and Molecular Metabolism, Faculty of Medicine
مصطلحات موضوعية: CHROMATIN-STATE DISCOVERY, NEGATIVE SELECTION, GENE, ARCHITECTURE, THEMIS, MECHANISMS, RISK, LOCI, 3123 Gynaecology and paediatrics
وصف الملف: application/pdf
العلاقة: The work was funded by the Academy of Finland (299200) and the European Foundation for Study of Diabetes (EFSD) Albert Renold Travel Grant to N.S., and a Strategic Award from the JDRF (4-SRA-2017-473-A-N) and the Wellcome (107212/A/15/Z) to J.A.T. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This study makes use of data generated by the Blueprint Consortium. A full list of the investigators who contributed to the generation of the data is available from www.blueprint-epigenome.eu.Funding for the project was provided by the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 282510 BLUEPRINT. The Genotype-Tissue Expression (GTEx) Project was supported by the Common Fund of the Office of the Director of the National Institutes of Health, and by NCI, NHGRI, NHLBI, NIDA, NIMH, and NINDS. The data used for the analyses described in this manuscript were obtained from the GTEx Portal (www.gtexportal.org).; Sandholm , N , Garcia , A R , Pekalski , M L , Inshaw , J R J , Cutler , A J & Todd , J A 2022 , ' Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants ' , Scientific Reports , vol. 12 , no. 1 , 14137 . https://doi.org/10.1038/s41598-022-18296-4Test; ORCID: /0000-0003-4322-6942/work/119581344; 20253a19-45ed-414a-ae06-b3645dea3ff0; http://hdl.handle.net/10138/348226Test; 000842561700070
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5دورية أكاديمية
المؤلفون: Zhang, Jia-Yuan, Hamey, Fiona, Trzupek, Dominik, Mickunas, Marius, Lee, Mercede, Godfrey, Leila, Yang, Jennie HM, Pekalski, Marcin L, Kennet, Jane, Waldron-Lynch, Frank, Evans, Mark L, Tree, Timothy IM, Wicker, Linda S, Todd, John A, Ferreira, Ricardo C
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.17863/CAM.92080Test
https://www.repository.cam.ac.uk/handle/1810/344656Test -
6دورية أكاديمية
المؤلفون: Ziegler, Anette-Gabriele, Arnolds, Stefanie, Kölln, Annika, Achenbach, Peter, Berner, Reinhard, Bonifacio, Ezio, Casteels, Kristina, Elding Larsson, Helena, Gündert, Melanie, Hasford, Joerg, Kordonouri, Olga, Lundgren, Markus, Oltarzewski, Mariusz, Pekalski, Marcin L, Pfirrmann, Markus, Snape, Matthew D, Szypowska, Agnieszka, Todd, John A
مصطلحات موضوعية: info:eu-repo/classification/ddc
وصف الملف: application/pdf
العلاقة: https://mediatum.ub.tum.de/1653368Test; https://mediatum.ub.tum.de/doc/1653368/document.pdfTest
الإتاحة: https://doi.org/10.1136/bmjopen-2021-052449Test
https://mediatum.ub.tum.de/1653368Test
https://mediatum.ub.tum.de/doc/1653368/document.pdfTest -
7رسالة جامعية
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8دورية أكاديمية
المؤلفون: Ferreira, Ricardo C, Castro Dopico, Xaquin, Oliveira, João J, Rainbow, Daniel B, Yang, Jennie H, Trzupek, Dominik, Todd, Sarah A, McNeill, Mhairi, Steri, Maristella, Orrù, Valeria, Fiorillo, Edoardo, Crouch, Daniel JM, Pekalski, Marcin L, Cucca, Francesco, Tree, Tim I, Vyse, Tim J, Wicker, Linda S, Todd, John A
المصدر: essn: 1664-3224 ; nlmid: 101560960
مصطلحات موضوعية: FOXP3, PD-1, PTPN22 Arg620Trp, autoimmunity, immunotherapy, regulatory T cells (Tregs), systemic lupus erythematosus (SLE), type I interferon, Adult, Aged, 80 and over, Alleles, Female, Forkhead Transcription Factors, Humans, Interleukin-2, Lupus Erythematosus, Systemic, Male, Middle Aged, Programmed Cell Death 1 Receptor, Protein Tyrosine Phosphatase, Non-Receptor Type 22, Risk, T-Lymphocytes, Regulatory, Young Adult
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.17863/CAM.47406Test
https://www.repository.cam.ac.uk/handle/1810/300332Test -
9دورية أكاديمية
المؤلفون: Ferreira, Ricardo C., Castro Dopico, Xaquin, Oliveira, João J., Rainbow, Daniel B., Yang, Jennie H., Trzupek, Dominik, Todd, Sarah A., McNeill, Mhairi, Steri, Maristella, Orrù, Valeria, Fiorillo, Edoardo, Crouch, Daniel J.M., Pekalski, Marcin L., Cucca, Francesco, Tree, Tim I., Vyse, Tim J., Wicker, Linda S., Todd, John A.
المصدر: Ferreira , R C , Castro Dopico , X , Oliveira , J J , Rainbow , D B , Yang , J H , Trzupek , D , Todd , S A , McNeill , M , Steri , M , Orrù , V , Fiorillo , E , Crouch , D J M , Pekalski , M L , Cucca , F , Tree , T I , Vyse , T J , Wicker , L S & Todd , J A 2019 , ' Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp ....
مصطلحات موضوعية: autoimmunity, FOXP3, immunotherapy, PD-1, PTPN22 ArgTrp, regulatory T cells (Tregs), systemic lupus erythematosus (SLE), type I interferon
الإتاحة: https://doi.org/10.3389/fimmu.2019.02606Test
https://kclpure.kcl.ac.uk/portal/en/publications/cc5d5fa9-8818-4eaa-8a5f-d1475afaf618Test
http://www.scopus.com/inward/record.url?scp=85075668360&partnerID=8YFLogxKTest -
10دورية أكاديمية
المؤلفون: Seelig, Eleonora, Howlett, James, Porter, Linsey, Truman, Lucy, Heywood, James, Kennet, Jane, Arbon, Emma L, Anselmiova, Katerina, Walker, Neil M, Atkar, Ravinder, Pekalski, Marcin L, Rytina, Ed, Evans, Mark, Wicker, Linda S, Todd, John A, Mander, Adrian P, Bond, Simon, Waldron-Lynch, Frank
مصطلحات موضوعية: Autoimmune diseases, Autoimmunity, Clinical Trials, Diabetes, T cells, Adolescent, Adult, Aged, Diabetes Mellitus, Type 1, Dose-Response Relationship, Drug, Drug Administration Schedule, Feasibility Studies, Female, Humans, Interleukin-2, Interleukin-2 Receptor alpha Subunit, Lymphocyte Activation, Lymphocyte Count, Male, Middle Aged, Recombinant Proteins, T-Lymphocytes, Regulatory, Treatment Outcome, Young Adult
وصف الملف: Electronic; application/pdf
الإتاحة: https://doi.org/10.17863/CAM.33037Test
https://www.repository.cam.ac.uk/handle/1810/285685Test