دورية أكاديمية
Contemporary results from the PelvEx collaborative: improvements in surgical outcomes for locally advanced and recurrent rectal cancer
| العنوان: | Contemporary results from the PelvEx collaborative: improvements in surgical outcomes for locally advanced and recurrent rectal cancer |
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| المؤلفون: | M Fahy, M E Kelly, N Abecasis, S N Akhtar, T Akiyoshi, M Alvarez-Gallego, M D Andric, P Arteaga-Asensio, H Assi, K K Austin, B Ayub, E Aytac, N Bacalbasa, I Balescu, S Baransi, G Baseckas, M R Bedford, P Berg, M Berle, J G Bloemen, N Borda-Arrizabalaga, B Bouyer, A Brannigan, E Brecelj, K Brown, M Brunner, Jwa Burger, A Burgess, E M Burns, C Byrne, S Carvalhal, J Cho, P Chong, S Connolly, M Coscia, M Cosimelli, P E Coyne, R S Croner, M Dattani, Q Denost, A L Desouza, E S Drozdov, I Edhemovic, J M Enriquez-Navascues, E Espín-Basany, A Etxart, M D Evans, F A Frizelle, N Galbraith, L Gentilini, D R Gill, D N Ginther, T Glyn, L Gould, A Gronchi, R Grützmann, D A Harris, A G Heriot, W Hohenberger, M Ito, J T Jenkins, Y Kanemitsu, M K Kazi, J S Keller, Shj Ketelaers, C E Koh, R Kokelaar, C Kontovounisios, B H Kye, B Lampe, J O Larkin, J M Lasso, Pjm Lee, Y S Lee, M Limbert, M L Lydrup, J Maciel, S Manfredelli, Cfs Marques, D McArthur, J J McCormick, P H McCormick, B J Mehigan, S Merkel, S Mikalauskas, J Mulsow, G Nason, Gap Nieuwenhuijzen, S Nordkamp, L Ozer, M Quinn, K Paarnio, I Pascual-Miguelañez, G Pellino, P Pezzuto, F Pfeffer, J Pinson, G Poggioli, D Proud, S Qiu, S Rasheed, E Rausa, S E Regenbogen, J M Rintala, G Robert, A C Rogers, A Romano, J Rothbarth, M Rottoli, C S Roxburgh, M Rutegard, H J Rutten, A P Saklani, T Sammour, R H Sayyed, M M Shaban, P Smart, M J Solomon, L Sorrentino, C W Steele, D Steffens, H Takala, P Tekkis, Y Tsukada, S Tsukamoto, J J Tuech, J M van Rees, W Vásquez-Jiménez, R Vather, C Verhoef, M Vierimaa, C J Wakeman, S K Warrier, P Waters, K Weber, A Williams, B Xavier, I Yildiz, R N Yoo, D C Winter |
| المساهمون: | M Fahy, M E Kelly, N Abecasis, S N Akhtar, T Akiyoshi, M Alvarez-Gallego, M D Andric, P Arteaga-Asensio, H Assi, K K Austin, B Ayub, E Aytac, N Bacalbasa, I Balescu, S Baransi, G Baseckas, M R Bedford, P Berg, M Berle, J G Bloemen, N Borda-Arrizabalaga, B Bouyer, A Brannigan, E Brecelj, K Brown, M Brunner, Jwa Burger, A Burgess, E M Burns, C Byrne, S Carvalhal, J Cho, P Chong, S Connolly, M Coscia, M Cosimelli, P E Coyne, R S Croner, M Dattani, Q Denost, A L Desouza, E S Drozdov, I Edhemovic, J M Enriquez-Navascues, E Espín-Basany, A Etxart, M D Evans, F A Frizelle, N Galbraith, L Gentilini, D R Gill, D N Ginther, T Glyn, L Gould, A Gronchi, R Grützmann, D A Harris, A G Heriot, W Hohenberger, M Ito, J T Jenkins, Y Kanemitsu, M K Kazi, J S Keller, Shj Ketelaers, C E Koh, R Kokelaar, C Kontovounisios, B H Kye, B Lampe, J O Larkin, J M Lasso, Pjm Lee, Y S Lee, M Limbert, M L Lydrup, J Maciel, S Manfredelli, Cfs Marques, D McArthur, J J McCormick, P H McCormick, B J Mehigan, S Merkel, S Mikalauskas, J Mulsow, G Nason, Gap Nieuwenhuijzen, S Nordkamp, L Ozer, M Quinn, K Paarnio, I Pascual-Miguelañez, G Pellino, P Pezzuto, F Pfeffer, J Pinson, G Poggioli, D Proud, S Qiu, S Rasheed, E Rausa, S E Regenbogen, J M Rintala, G Robert, A C Rogers, A Romano, J Rothbarth, M Rottoli, C S Roxburgh, M Rutegard, H J Rutten, A P Saklani, T Sammour, R H Sayyed, M M Shaban, P Smart, M J Solomon, L Sorrentino, C W Steele, D Steffens, H Takala, P Tekkis, Y Tsukada, S Tsukamoto, J J Tuech, J M van Rees, W Vásquez-Jiménez, R Vather, C Verhoef, M Vierimaa, C J Wakeman, S K Warrier, P Waters, K Weber, A Williams, B Xavier, I Yildiz, R N Yoo, D C Winter |
| سنة النشر: | 2024 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | international collaboration, locally advanced, rectal cancer, surgical outcome, survival outcomes |
| الوصف: | Aim: The PelvEx Collaborative collates global data on outcomes following exenterative surgery for locally advanced and locally recurrent rectal cancer (LARC and LRRC, respectively). The aim of this study is to report contemporary data from within the collaborative and benchmark it against previous PelvEx publications. Method: Anonymized data from 45 units that performed pelvic exenteration for LARC or LRRC between 2017 and 2021 were reviewed. The primary endpoints were surgical outcomes, including resection margin status, radicality of surgery, rates of reconstruction and associated morbidity and/or mortality. Results: Of 2186 patients who underwent an exenteration for either LARC or LRRC, 1386 (63.4%) had LARC and 800 (36.6%) had LRRC. The proportion of males to females was 1232:954. Median age was 62 years (interquartile range 52-71 years) compared with a median age of 63 in both historical LARC and LRRC cohorts. Compared with the original reported PelvEx data (2004-2014), there has been an increase in negative margin (R0) rates from 79.8% to 84.8% and from 55.4% to 71.7% in the LARC and LRRC cohorts, respectively. Bone resection and flap reconstruction rates have increased accordingly in both cohorts (8.2%-19.6% and 22.6%-32% for LARC and 20.3%-41.9% and 17.4%-32.1% in LRRC, respectively). Despite this, major morbidity has not increased. Conclusion: In the modern era, patients undergoing pelvic exenteration for advanced rectal cancer are undergoing more radical surgery and are more likely to achieve a negative resection margin (R0) with no increase in major morbidity. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/38566456; volume:epub ahed of print; firstpage:1; lastpage:6; numberofpages:6; journal:COLORECTAL DISEASE; https://hdl.handle.net/11585/967097Test |
| DOI: | 10.1111/codi.16948 |
| الإتاحة: | https://doi.org/10.1111/codi.16948Test https://hdl.handle.net/11585/967097Test |
| رقم الانضمام: | edsbas.C7391E97 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/codi.16948 |
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