المؤلفون: AndréR.A. Marques, Mina Mirzaian, Hisako Akiyama, Patrick Wisse, Maria J. Ferraz, Paulo Gaspar, Karen Ghauharali-van der Vlugt, Rianne Meijer, Pilar Giraldo, Pilar Alfonso, Pilar Irún, Maria Dahl, Stefan Karlsson, Elena V. Pavlova, Timothy M. Cox, Saskia Scheij, Marri Verhoek, Roelof Ottenhoff, CindyP.A.A. van Roomen, Navraj S. Pannu, Marco van Eijk, Nick Dekker, Rolf G. Boot, Herman S. Overkleeft, Edward Blommaart, Yoshio Hirabayashi, Johannes M. Aerts

المصدر: Journal of Lipid Research, Vol 57, Iss 3, Pp 451-463 (2016)

مصطلحات موضوعية: glucosyl-β-D-cholesterol, glucosylceramide, glucocerebrosidase, Gaucher disease, Niemann-Pick type C disease, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520354444Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/57f08df9b338494281ce0b82ea7d752aTest

المؤلفون: Cindy P. A. A. van Roomen, Ewout Foppen, Mina Mirzaian, Sander Kooijman, Saskia Scheij, Herman S. Overkleeft, Chun-Xia Yi, Roelof Ottenhoff, Marco van Eijk, Clarita Mergen, Patrick C.N. Rensen, Yanan Wang, Kirstin Jansen, Daniela Herrera Moro Chao, Matthias H. Tschöp, Johannes M. F. G. Aerts, Edwin T. Parlevliet, Marri Verhoek, Dawei Wang, André Marques, Rolf G. Boot, Andries Kalsbeek, Randy J. Seeley

المساهمون: University of Zurich, Aerts, Johannes M F G, Netherlands Institute for Neuroscience (NIN), Laboratory for Endocrinology, Medical Biochemistry, ACS - Atherosclerosis & ischemic syndromes, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Gastroenterology Endocrinology Metabolism, Endocrinology, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Cardiovascular Sciences, APH - Aging & Later Life

المصدر: Diabetes, 68(12), 2223-2234. AMER DIABETES ASSOC
Diabetes 68, 2223-2234 (2019)
Diabetes, 68(12), 2223-2234
Diabetes, 68, 2223-2234. American Diabetes Association Inc.
Diabetes, 68(12), 2223-2234. American Diabetes Association Inc.

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, 1-Deoxynojirimycin, Endocrinology, Diabetes and Metabolism, Iminosugar, Adipose tissue, Adamantane, 610 Medicine & health, 030209 endocrinology & metabolism, Satiation, Carbohydrate metabolism, Mice, 03 medical and health sciences, Endocrinology, 0302 clinical medicine, Adipose Tissue, Brown, Glucagon-Like Peptide 1, 10183 Swiss Institute of Allergy and Asthma Research, Internal medicine, Brown adipose tissue, Internal Medicine, medicine, Animals, Glucose homeostasis, Secretion, Obesity, Rats, Wistar, Receptor, business.industry, Antagonist, Brain, Rats, Mice, Inbred C57BL, Diabetes and Metabolism, 2712 Endocrinology, Diabetes and Metabolism, Glucose, 030104 developmental biology, medicine.anatomical_structure, 2724 Internal Medicine, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6eeea7db358776e32d871b6706e3ba6Test
https://hdl.handle.net/1887/3199006Test

المؤلفون: Rolf G Boot, Marri Verhoek, Maaike De Fost, Carla E M Hollak, Mario Maas, Boris Bleijlevens, Marielle J, Van Breemen, Marjan Van Meurs, Leonie A Boven, Jon D Laman, Mary Teresa Moran, Timothy M Cox, Johannes M F G Aerts, Interleukins Articles, Rolf G. Boot, Carla E. M. Hollak, Marielle J. Van Breemen, Leonie A. Boven, Jon D. Laman, Timothy M. Cox, Johannes M. F. G. Aerts

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bloodjournal.hematologylibrary.org/content/early/2003/09/11/blood-2003-05-1612.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.326.5580Test; http://bloodjournal.hematologylibrary.org/content/early/2003/09/11/blood-2003-05-1612.full.pdfTest

الإتاحة: http://bloodjournal.hematologylibrary.org/content/early/2003/09/11/blood-2003-05-1612.full.pdfTest

المؤلفون: Rolf G. Boot, Marri Verhoek, Maaike De Fost, Carla E. M. Hollak, Mario Maas, Boris Bleijlevens, Marielle J. Van Breemen, Marjan Van Meurs, Leonie A. Boven, Jon D. Laman, Mary Teresa Moran, Timothy M. Cox, Johannes M. F. G. Aerts, Interleukins Articles

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bloodjournal.hematologylibrary.org/content/103/1/33.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.881Test; http://bloodjournal.hematologylibrary.org/content/103/1/33.full.pdfTest

الإتاحة: http://bloodjournal.hematologylibrary.org/content/103/1/33.full.pdfTest

المؤلفون: Shoichiro Ohta, Ulf Hammar, Cilla Söderhäll, Barbro Dahlén, Kenji Izuhara, Sven-Erik Dahlén, Maciej Kupczyk, Juha Kere, Anna James, Elisabeth H. Bel, Rolf G. Boot, Junya Ono, Lovisa E. Reinius, Marri Verhoek, Anna Gomes

المساهمون: Other departments, AII - Amsterdam institute for Infection and Immunity, Pulmonology

المصدر: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
American Journal of Respiratory and Critical Care Medicine, 193(2), 131-142. AMER THORACIC SOC
American journal of respiratory and critical care medicine, 193(2), 131-142. American Thoracic Society
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193(2), 131-142

مصطلحات موضوعية: Male, 0301 basic medicine, AIRWAY INFLAMMATION, Disease, Critical Care and Intensive Care Medicine, Severity of Illness Index, Pulmonary Disease, Chronic Obstructive, chitotriosidase, 0302 clinical medicine, Lectins, Multicenter Studies as Topic, Longitudinal Studies, Young adult, Chitinase-3-Like Protein 1, COPD, CHITINASE-LIKE PROTEIN, Smoking, GENETIC-VARIATION, Middle Aged, Europe, LUNG-FUNCTION, Hexosaminidases, ATOPIC ASTHMA, Disease Progression, Regression Analysis, Female, Steroids, Adult, Pulmonary and Respiratory Medicine, medicine.medical_specialty, YKL-40, Adolescent, MAMMALIAN CHITINASE, Adipokine, CHI3L1, chronic obstructive pulmonary disease, Young Adult, 03 medical and health sciences, Adipokines, Internal medicine, 3-LIKE 1, Severity of illness, medicine, Humans, ALLERGEN CHALLENGE, MATRIX PROTEIN, Aged, Asthma, Polymorphism, Genetic, business.industry, GLYCOSYL HYDROLASES, asthma, medicine.disease, respiratory tract diseases, 030104 developmental biology, 030228 respiratory system, Immunology, business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fd11685d715b2e1a44c7d991a228aeTest
https://doi.org/10.1164/rccm.201504-0760ocTest

المؤلفون: Adrianus M. C. H. van den Nieuwendijk, Daniel Mink, Veronica Coco Rohde, Gijsbert A. van der Marel, Jianbing Jiang, Daniel W. Wright, Bogdan I. Florea, Johannes M. F. G. Aerts, Gideon J. Davies, Wouter W. Kallemeijn, Hans van den Elst, Wilma E. Donker-Koopman, Martin Schürmann, Nan Li, Rolf G. Boot, Saskia Scheij, Marri Verhoek, Jeroen D. C. Codée, Herman S. Overkleeft, Elisa Colomina Folch

المساهمون: Other departments, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences

المصدر: CHEMICAL SCIENCE, 6(5), 2782-2789. Royal Society of Chemistry
Chemical Science, 6(5), 2782-2789

مصطلحات موضوعية: biology, genetic structures, 010405 organic chemistry, Stereochemistry, Chemistry, Activity-based proteomics, Active site, Stereoisomerism, General Chemistry, 010402 general chemistry, medicine.disease, biology.organism_classification, 01 natural sciences, Fucosidosis, In vitro, 0104 chemical sciences, 3. Good health, Biochemistry, In vivo, Hydrolase, medicine, biology.protein, Bacteria

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c1b0655d1799327f935b9d7fee32e0Test
https://doi.org/10.1039/c4sc03739aTest

المؤلفون: Johannes M. F. G. Aerts, Marri Verhoek, Timothy M. Cox, Elena Pavlova, Wilma E. Donker-Koopman, Rolf G. Boot, Jessica K. Nelson, Gert Jan Kramer, Wouter W. Kallemeijn, Mary Teresa Moran, Wouter Wegdam, Roelof Ottenhoff, Jon D. Laman, Marco van Eijk, Paulo Gaspar, Tanit L. Gabriel, Johannes P. C. Vissers

المساهمون: Cox, Timothy [0000-0002-4951-9941], Pavlova, Elena [0000-0003-0187-5098], Apollo - University of Cambridge Repository, Molecular Neuroscience and Ageing Research (MOLAR), Translational Immunology Groningen (TRIGR), Other departments, Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences, AII - Amsterdam institute for Infection and Immunity

المصدر: FEBS Open Bio
FEBS Open Bio, 6(9), 902-913. Wiley-Blackwell
FEBS Open Bio, 6(9), 902-913. Wiley Open Access
FEBS open bio, 6(9), 902-913. Wiley-Blackwell

مصطلحات موضوعية: 0301 basic medicine, DC-HIL, EXPRESSION, GLUCOCEREBROSIDASE, Pathology, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Genetic enhancement, Cell, DC‐HIL, Biology, storage disease, PHENOTYPE, osteoactivin, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chitotriosidase, Lysosome, glucosylceramide, medicine, CELL, Research Articles, GPNMB, PLASMA, CCL18, GENE-THERAPY, nutritional and metabolic diseases, FORMATION IN-VIVO, Phenotype, 3. Good health, MARKED ELEVATION, nervous system diseases, 030104 developmental biology, medicine.anatomical_structure, DIFFERENTIATION, lysosome, Biomarker (medicine), Glucocerebrosidase, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9904b801f366cbc06c3d1033778f123cTest
https://www.repository.cam.ac.uk/handle/1810/289591Test

المؤلفون: Saskia Scheij, Cécile M. J. Ouairy, Anneke Strijland, Marri Verhoek, Monique D. Appelman, Rolf G. Boot, André Marques, D. Lahav, Mina Mirzaian, Maria J. Ferraz, Herman S. Overkleeft, Patrick Wisse, Johannes M. F. G. Aerts

المساهمون: Graduate School, Other departments, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences

المصدر: FEBS letters, 590(6), 716-725. Wiley-Blackwell

مصطلحات موضوعية: 0301 basic medicine, Male, Acid Ceramidase, Acylation, Biophysics, Biochemistry, Glycosphingolipids, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structural Biology, Genetics, medicine, Animals, Humans, Glycoside hydrolase, Molecular Biology, Mice, Knockout, Alpha-galactosidase, Gaucher Disease, biology, Cell Biology, Glycosphingolipid, Metabolism, medicine.disease, Fabry disease, Glucosylceramidase, Disease Models, Animal, 030104 developmental biology, HEK293 Cells, chemistry, alpha-Galactosidase, biology.protein, Fabry Disease, Female, Lysosomes, Glucocerebrosidase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd5a38298fa91df3dfa4e3077a1dc56Test
https://doi.org/10.1002/1873-3468.12104Test

المؤلفون: Marco van Eijk, Rolf G. Boot, Yoshio Hirabayashi, E. F. C. Blommaart, Pilar Giraldo, Paulo Gaspar, Nick Dekker, Rianne Meijer, Roelof Ottenhoff, Mina Mirzaian, Elena Pavlova, Navraj S. Pannu, Maria Dahl, Pilar Irún, Johannes M. F. G. Aerts, Saskia Scheij, Karen Ghauharali-van der Vlugt, Stefan Karlsson, Timothy M. Cox, Maria J. Ferraz, Pilar Alfonso, Patrick Wisse, Herman S. Overkleeft, Marri Verhoek, André Marques, Hisako Akiyama, Cindy P. A. A. van Roomen

المساهمون: Pavlova, Elena [0000-0003-0187-5098], Cox, Timothy [0000-0002-4951-9941], Apollo - University of Cambridge Repository, Other departments, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, Graduate School, AII - Amsterdam institute for Infection and Immunity, ACS - Amsterdam Cardiovascular Sciences

المصدر: Journal of Lipid Research, Vol 57, Iss 3, Pp 451-463 (2016)
Journal of Lipid Research
Journal of lipid research, 57(3), 451-463. American Society for Biochemistry and Molecular Biology Inc.

مصطلحات موضوعية: 0301 basic medicine, Male, Glycosylation, Niemann-Pick type C disease, QD415-436, Biology, Biochemistry, Cercopithecus aethiops, 03 medical and health sciences, chemistry.chemical_compound, Mice, Endocrinology, Lysosome, glucosylceramide, Chlorocebus aethiops, medicine, Animals, Humans, Research Articles, Niemann-Pick Diseases, COS cells, Gaucher Disease, Cholesterol, glucocerebrosidase, beta-Glucosidase, glucosyl-β-D-cholesterol, Cell Biology, In vitro, Sterol, Cell biology, 030104 developmental biology, medicine.anatomical_structure, RAW 264.7 Cells, chemistry, COS Cells, biology.protein, Female, Glucocerebrosidase, Glucosidases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce37df56ec0df699dc973d8fe40b72fTest
https://doi.org/10.1194/jlr.m064923Test

المؤلفون: Carla E. M. Hollak, Mina Mirzaian, Patrick Wisse, Maria J. Ferraz, Herman S. Overkleeft, Johannes M. F. G. Aerts, Bouwien E. Smid, Marri Verhoek

المساهمون: Amsterdam Gastroenterology Endocrinology Metabolism, Endocrinology, Graduate School, Other departments, Medical Biochemistry, Amsterdam Cardiovascular Sciences

المصدر: Orphanet Journal of Rare Diseases
Orphanet journal of rare diseases, 11(1). BioMed Central
Orphanet Journal of Rare Diseases, 11, 28

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, 1-Deoxynojirimycin, Pyrrolidines, Disease, Glucosylceramides, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Miglustat, medicine, Humans, Genetics(clinical), Pharmacology (medical), Substrate reduction therapy, Enzyme Inhibitors, Genetics (clinical), Eliglustat, Chitotriosidase, Medicine(all), Gaucher Disease, business.industry, Research, CCL18, nutritional and metabolic diseases, General Medicine, Enzyme replacement therapy, Blood proteins, Glucosylceramidase, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, Glucosylsphingosine, Glucosylceramide, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4346b8d3c90c6f1429341c58c8d6fce1Test
https://doi.org/10.1186/s13023-016-0413-3Test