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1دورية أكاديمية
المؤلفون: W Joon Chung, Jennifer L Goeckeler-Fried, Viktoria Havasi, Annette Chiang, Steven M Rowe, Zackery E Plyler, Jeong S Hong, Marina Mazur, Gary A Piazza, Adam B Keeton, E Lucile White, Lynn Rasmussen, Allan M Weissman, R Aldrin Denny, Jeffrey L Brodsky, Eric J Sorscher
المصدر: PLoS ONE, Vol 11, Iss 10, p e0163615 (2016)
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC5061379?pdf=renderTest; https://doaj.org/toc/1932-6203Test
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2
المؤلفون: Christina M. Camara, Anita Thakur, Wissam Mansour, Urszula Nowicka, Frank Parlati, Daoning Zhang, Raymond J. Deshaies, Susan Krueger, Carlos A. Castañeda, Steven M. Bonn, Ortal Hayat, Michael H. Glickman, Jeffrey L. Brodsky, Mark A. Nakasone, Jennifer L. Goeckeler-Fried, Olivier Walker, Tsui-Fen Chou, Timothy A. Lewis, David Fushman
المساهمون: Biophysics of complex systems, Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Ctr Biomol Struct & Org, University of Maryland [College Park], University of Maryland System-University of Maryland System, Ctr Neutron Res, National Institute of Standards and Technology [Gaithersburg] (NIST), Department of Biology - Institute of Technology, Technion - Israel Institute of Technology [Haifa], We thank George H. Lorimer and Arnon Henn for access to their fluorimeters, Ananya Majumdar for help with setting up triple-resonance NMR experiments, Rajesh Singh for the Rub1 sample, Allan Weissman for RCC4 cells, and Konstantin Berlin for useful discussions. The project has been funded in part from the NCI Initiative for Chemical Genetics, NIH, under contract no. N01-CO-12400 to Stuart L. Schreiber, by NIH grants GM065334 to D.F. and GM095755 to D.F. and M.H.G., ISF grant 909-14 to M.H.G., and by NIH grants GM075061 and DK079307 and by Cystic Fibrosis Foundation Therapeutics grant BRODSK13XXO to J.L.B., and a Fulbright postdoctoral fellowship to M.A.N., and utilized NMR instrumentation supported in part by NSF grant DBI1040158 and neutron-scattering facilities supported in part by the NSF under agreement no. DMR-0944772. R.J.D. is a founder and shareholder of Cleave Biosciences, which is developing drugs that target the ubiquitin system., Technion-Israel Institute of Technology
المصدر: Structure
Structure, Elsevier (Cell Press), 2017, 25 (12), pp.1839-1855.e11. ⟨10.1016/j.str.2017.10.007⟩مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Sulfanilic Acids, Saccharomyces cerevisiae, Ubiquitin-conjugating enzyme, 010402 general chemistry, 01 natural sciences, Article, Cell Line, Deubiquitinating enzyme, 03 medical and health sciences, Ubiquitin, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Structural Biology, medicine, Humans, Ubiquitins, Molecular Biology, ComputingMilieux_MISCELLANEOUS, Binding Sites, biology, Small molecule, 0104 chemical sciences, 3. Good health, Ubiquitin ligase, Cell biology, Molecular Docking Simulation, 030104 developmental biology, Proteasome, Biochemistry, Quinolines, biology.protein, Proteasome inhibitor, HeLa Cells, Protein Binding, medicine.drug, Deubiquitination
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfec4eed37788062c40d159ac6f34b69Test
https://doi.org/10.1016/j.str.2017.10.007Test