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المؤلفون: Jörg R. P. Geiger, Henrike Planert, Franz Xaver Mittermaier, Henrik Alle, Ulf C. Schneider, Yangfan Peng
المصدر: eLife
eLife, Vol 8 (2019)مصطلحات موضوعية: Patch-Clamp Techniques, Mouse, QH301-705.5, Computer science, Science, Cortical slice, General Biochemistry, Genetics and Molecular Biology, Software, Automated patch clamp, Humans, Patch clamp, Biology (General), Throughput (business), microcircuit, Neurons, General Immunology and Microbiology, Subthreshold conduction, business.industry, General Neuroscience, multipatch, Pipette, Brain, Usability, Small sample, General Medicine, human physiology, Tools and Resources, connectivity, Medicine, Rat, Nerve Net, business, automated patch-clamp, human cortex, Neuroscience, Human
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455ff15bf59cc2957b125ea55e0bbbcdTest
https://doi.org/10.7554/elife.48178Test -
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المصدر: PLoS ONE, Vol 16, Iss 3, p e0243645 (2021)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Physiology, Action Potentials, Biochemistry, Ion Channels, 0302 clinical medicine, Calcium Channels, N-Type, Automated patch clamp, Transient Transfection Assay, Cricetinae, Medicine and Health Sciences, Membrane Electrophysiology, Analgesics, Multidisciplinary, Chemistry, Physics, NAV1.7 Voltage-Gated Sodium Channel, Transfection, Electrophysiology, Bioassays and Physiological Analysis, Physical Sciences, 293T cells, Cell lines, Medicine, Biological cultures, Research Article, Science, Biophysics, Neurophysiology, Pain, CHO Cells, Research and Analysis Methods, Calcium Phosphate Transfection, 03 medical and health sciences, Signs and Symptoms, Cricetulus, FuGENE, Animals, Humans, Patch clamp, Molecular Biology Techniques, Molecular Biology, Ion channel, Voltage-gated ion channel, Sodium channel, Electrophysiological Techniques, Biology and Life Sciences, Proteins, High-Throughput Screening Assays, 030104 developmental biology, HEK293 Cells, Microscopy, Fluorescence, Lipofectamine, Calcium Channels, Clinical Medicine, Patch Clamp Techniques, 030217 neurology & neurosurgery, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b541cc5ff952fab70a9d767a58884ec2Test
https://doaj.org/article/f089b070a4b446cb8df4ca680b12c11cTest -
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المؤلفون: Abby Sewell, Glenn E. Kirsch, Caiyun Wu, Arianne L. Motter, Fedorov Nikolai, Yuri A. Kuryshev, Lucas C. Armstrong, Michael S. Orr, Zhiqi Liu, Carmine Leggett
المصدر: Slas Discovery
مصطلحات موضوعية: 0301 basic medicine, Agonist, Patch-Clamp Techniques, medicine.drug_class, Genetic Vectors, Gene Expression, Receptors, Nicotinic, Pharmacology, Nucleus accumbens, Transfection, Biochemistry, Cell Line, Analytical Chemistry, Small Molecule Libraries, Nicotine, 03 medical and health sciences, 0302 clinical medicine, Automated patch clamp, Drug Discovery, medicine, Humans, Patch clamp, nicotinic acetylcholine receptor, Cloning, Molecular, Original Research, Acetylcholine receptor, Chemistry, Electrophysiological Phenomena, High-Throughput Screening Assays, Protein Subunits, Nicotinic acetylcholine receptor, 030104 developmental biology, Nicotinic agonist, ion channel, electrophysiological screening, Molecular Medicine, automated patch clamp, Ion Channel Gating, 030217 neurology & neurosurgery, Biotechnology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1e31ebce6f9b777c6201a00c062cd3Test
https://doi.org/10.1177/2472555217696794Test -
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المؤلفون: Teun P. de Boer, Alison Obergrussberger, Nadine Becker, Niels Fertig, Toon A.B. van Veen, Sonja Stoelzle-Feix, Marc A. Vos, Birgit Goversen
المصدر: Frontiers in Physiology, Vol 8 (2018)
مصطلحات موضوعية: 0301 basic medicine, lcsh:QP1-981, Physiology, Computer science, Safety pharmacology, cardiomyocyte, lcsh:Physiology, stem cell, 03 medical and health sciences, Electrophysiology, 030104 developmental biology, Clamp, Automated patch clamp, dynamic clamp, safety pharmacology, Physiology (medical), Current clamp, automated patch clamp electrophysiology, Patch clamp, Hybrid model, Ion channel, inward rectifying potassium ion channels, Biomedical engineering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c66f6050b475e17bc308f0a8cec065eTest
https://doi.org/10.3389/fphys.2017.01094Test -
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المؤلفون: Claudia Haarmann, Max Mueller, Juergen Steindl, Alison Obergrussberger, Andrea Brüggemann, Johannes Stiehler, Atsushi Ohtsuki, Niels Fertig, Nadine Becker, Marius Vogel, Tom A. Goetze, Ilka Rinke, Michael George, Takayuki Oka, Timo Stengel, Markus Rapedius
المصدر: SLAS Technology. 21:779-793
مصطلحات موضوعية: 0301 basic medicine, Patch-Clamp Techniques, Materials science, hERG, Receptors, Cell Surface, Ion Channels, Cell Line, 03 medical and health sciences, Automated patch clamp, Electronic engineering, Animals, Humans, Patch clamp, Ion channel, Automation, Laboratory, Voltage-gated ion channel, biology, Amplifier, Pipette, Robotics, High-Throughput Screening Assays, Computer Science Applications, Medical Laboratory Technology, 030104 developmental biology, biology.protein, Ligand-gated ion channel, Biomedical engineering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c31bb0ac574bd86f5dc089b001c3acTest
https://doi.org/10.1177/2211068215623209Test -
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المؤلفون: Brendan M. Callahan, Rachael L. Neve, Zhaolun Su, Craig R. Forest, Alexander A. Chubykin, Edward S. Boyden, Hongkui Zeng, Qiuyu Wu, Ilya Kolb, William A. Stoy, Suhasa B. Kodandaramaiah
المصدر: Journal of Neurophysiology. 116:1564-1578
مصطلحات موضوعية: Male, 0301 basic medicine, Patch-Clamp Techniques, Time Factors, Physiology, Computer science, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Mice, Transgenic, Tissue Culture Techniques, User-Computer Interface, 03 medical and health sciences, 0302 clinical medicine, Automated patch clamp, Computer Graphics, Image Processing, Computer-Assisted, Animals, Computer vision, Patch clamp, ComputingMethodologies_COMPUTERGRAPHICS, Fluorescent Dyes, Visual Cortex, Automation, Laboratory, Neurons, business.industry, General Neuroscience, Pipette, Immunohistochemistry, Mice, Inbred C57BL, 030104 developmental biology, Microscopy, Fluorescence, Calibration, Innovative Methodology, Female, Artificial intelligence, business, Algorithms, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcc6ee487c2e3a7d000b644b7ff5bfbTest
https://doi.org/10.1152/jn.00386.2016Test -
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المؤلفون: David J. Gavaghan, Ken Wang, Michael Clerx, Chon Lok Lei, Liudmila Polonchuk, Gary R. Mirams
المصدر: Biophysical Journal
مصطلحات موضوعية: Computer science, Voltage clamp, hERG, Biophysics, Gating, CHO Cells, Bayesian inference, 03 medical and health sciences, Automation, 0302 clinical medicine, Cricetulus, Single-cell analysis, Automated patch clamp, Computing & Mathematics - Applied Mathematics, Animals, Humans, Patch clamp, Throughput (business), Ion channel, 030304 developmental biology, Protocol (science), 0303 health sciences, biology, Mathematical model, business.industry, Centre for Mathematical Medicine and Biology, Bayes Theorem, Articles, Potassium channel, Ether-A-Go-Go Potassium Channels, Kinetics, biology.protein, Single-Cell Analysis, business, Biological system, 030217 neurology & neurosurgery, Communication channel
وصف الملف: PDF
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62fd21b3a91ba2c8d4b097be629ae63Test
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المؤلفون: Sylvain Feliciangeli, Vincent Probst, B.B. Ribeiro de Oliveira Mendes, Franck C. Chatelain, B. Ollivier, Jérôme Montnach, F. Kyndt, S. Nicolas, Florian Lesage, Gildas Loussouarn, Isabelle Denjoy, M. De Waard
المصدر: Archives of Cardiovascular Diseases Supplements. 12:257
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, biology, business.industry, High-throughput screening, Electroporation, hERG, Transfection, Computational biology, Potassium channel, Automated patch clamp, FuGENE, biology.protein, Medicine, cardiovascular diseases, Patch clamp, Cardiology and Cardiovascular Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::48b64222c03c0b877391f85d739f4066Test
https://doi.org/10.1016/j.acvdsp.2020.03.138Test -
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المؤلفون: Fajun Nan, Zhaobing Gao, Jinfeng Yue, Guan-hua Qiao, Ni Liu
المصدر: Acta Pharmacologica Sinica. 37:105-110
مصطلحات موضوعية: 0301 basic medicine, Screening techniques, Patch-Clamp Techniques, High-throughput screening, chemistry.chemical_element, CHO Cells, Fluorescence, 03 medical and health sciences, Cricetulus, Automated patch clamp, High-Throughput Screening Assays, Barracuda, Animals, KCNQ2 Potassium Channel, Pharmacology (medical), Patch clamp, Thallium, Pharmacology, Chromatography, Traditional medicine, biology, General Medicine, biology.organism_classification, 030104 developmental biology, chemistry, Original Article, Ion Channel Gating, Databases, Chemical
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aaba1297759526557a8c8e15b3c9f1Test
https://doi.org/10.1038/aps.2015.142Test -
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المؤلفون: Sonja Stölzle-Feix, Nadine Becker, Alison Obergrussberger, Andrea Brüggemann, Clemens Möller, Niels Fertig
المصدر: Channels
مصطلحات موضوعية: Patch-Clamp Techniques, Biophysics, Quantitative Structure-Activity Relationship, Nanotechnology, cardiomyocytes, Review, Biochemistry, Ion, Cell membrane, Small Molecule Libraries, action potential, Automated patch clamp, safety pharmacology, Drug Discovery, medicine, Potassium Channel Blockers, Animals, Humans, Patch clamp, Integral membrane protein, Ion channel, Chemistry, screening, ion channels, temperature, High-Throughput Screening Assays, Electrophysiology, medicine.anatomical_structure, impedance, Flux (metabolism), Sodium Channel Blockers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2d55d35260852adabdde2d95a3d964Test
http://europepmc.org/articles/PMC4850050Test
