نتائج البحث

1

Elevated angiotensin II induces platelet apoptosis through promoting oxidative stress in an AT1R‐dependent manner during sepsis

المؤلفون: Dun-Feng Xu, Yu-Jian Liu, Chu-Fan Xu, Yan Wang, Yan-Fei Mao, Lai Jiang, Xiao-Yan Zhu

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, thrombocytopenia, Apoptosis, Pharmacology, medicine.disease_cause, Mice, 0302 clinical medicine, Platelet, Cells, Cultured, platelet, Aged, 80 and over, chemistry.chemical_classification, Angiotensin II, Middle Aged, Prognosis, Losartan, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, Female, Signal Transduction, medicine.drug, Adult, Blood Platelets, reactive oxygen species (ROS), Receptor, Angiotensin, Type 1, Sepsis, 03 medical and health sciences, medicine, Animals, Humans, angiotensin II (Ang II), Aged, Cell Proliferation, Reactive oxygen species, Intrinsic apoptosis, angiotensin II receptor blocker (ARB), Original Articles, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Gene Expression Regulation, chemistry, Case-Control Studies, Reactive Oxygen Species, Angiotensin II Type 1 Receptor Blockers, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6123010f834858f85232068229ee63deTest
https://doi.org/10.1111/jcmm.16382Test

2

NRP1 and MMP9 are dual targets of RNA‐binding protein QKI5 to alter VEGF‐R/ NRP1 signalling in trophoblasts in preeclampsia

المؤلفون: Xingyu Yang, Biwei He, Dan Chen, Weiwei Cheng

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Adult, medicine.medical_treatment, MMP9, preeclampsia, 03 medical and health sciences, Mice, 0302 clinical medicine, Pre-Eclampsia, In vivo, Cell Movement, Pregnancy, Neuropilin 1, medicine, NRP1, QKI5, Animals, Humans, Secretion, Cell Proliferation, Cell growth, Chemistry, Growth factor, Trophoblast, RNA-Binding Proteins, Cell Biology, Original Articles, trophoblast, Hedgehog signaling pathway, Neuropilin-1, Cell biology, Trophoblasts, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Receptors, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Case-Control Studies, Molecular Medicine, Original Article, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4918015cab186bc5d21a6f1f0b02e93Test
http://europepmc.org/articles/PMC8184681Test

3

SLAM/SAP Decreased Follicular Regulatory T Cells in Patients with Graves’ Disease

المؤلفون: Zhigang Hu, Jun Yang, Huaxi Xu, Shengjun Wang, Yingzhao Liu, Jie Tian, Xinyi Tang, Huiyong Peng, Lina Geng

المصدر: Journal of Immunology Research
Journal of Immunology Research, Vol 2021 (2021)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Article Subject, Graves' disease, Immunology, T-Lymphocytes, Regulatory, CD19, CXCR5, 03 medical and health sciences, 0302 clinical medicine, Signaling lymphocytic activation molecule, Signaling Lymphocytic Activation Molecule Family Member 1, Internal medicine, Follicular phase, medicine, Humans, Immunology and Allergy, Lymphocyte Count, Signaling Lymphocytic Activation Molecule Associated Protein, 030304 developmental biology, B-Lymphocytes, 0303 health sciences, biology, Chemistry, Autoantibody, FOXP3, General Medicine, RC581-607, Middle Aged, medicine.disease, Graves Disease, Healthy Volunteers, Endocrinology, Case-Control Studies, biology.protein, Female, Immunologic diseases. Allergy, Signal transduction, Research Article, Signal Transduction, 030215 immunology

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2a9715506ca7ff9eec6bf36d941ed6Test
https://doi.org/10.1155/2021/5548463Test

4

TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc

المؤلفون: Snuggs J, Shannon N. Tessier, Makarand V. Risbud, Irving M. Shapiro, R A B Bunning, C. L. Le Maitre

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cell biology, Nucleus Pulposus, Molecular biology, Science, Primary Cell Culture, Aquaporin, Intervertebral Disc Degeneration, Article, Mice, 03 medical and health sciences, Rheumatic diseases, Chondrocytes, 0302 clinical medicine, Downregulation and upregulation, Enhancer binding, Gene expression, Animals, Humans, RNA, Small Interfering, Rats, Wistar, Mice, Knockout, Gene knockdown, Multidisciplinary, Aquaporin 1, Osmotic concentration, Chemistry, Osmolar Concentration, Middle Aged, Aquaporin 5, Rats, Mice, Inbred C57BL, Mechanisms of disease, 030104 developmental biology, Gene Expression Regulation, Tonicity, Medicine, Female, 030217 neurology & neurosurgery, Signal Transduction, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee143d3c36cf2973f715cac5f156fecTest
https://doaj.org/article/4138b596e4be471abac6b99852763239Test

5

Reversal of Abnormal CD4+ T Cell Metabolism Alleviates Thyroiditis by Deactivating the mTOR/HIF1a/Glycolysis Pathway

المؤلفون: Shiqi Wang, Zhongyan Shan, Qiong Wu, Xiaoli Wang, Xiaoguang Shi, Lei Zhao, Weiping Teng

المصدر: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, T cell, immunometabolism, Tregs, Hashimoto Disease, HIF1a, Deoxyglucose, Thyroiditis, Diseases of the endocrine glands. Clinical endocrinology, Autoimmune thyroiditis, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Internal medicine, medicine, Animals, Humans, Glycolysis, Thyroiditis, Subacute, PI3K/AKT/mTOR pathway, Original Research, Aged, Glucose Transporter Type 1, Chemistry, TOR Serine-Threonine Kinases, Thyroid, Hashimoto’s thyroiditis, glycolysis, Middle Aged, Th1 Cells, medicine.disease, RC648-665, Hypoxia-Inducible Factor 1, alpha Subunit, Metformin, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, T cell differentiation, Th17 Cells, Female, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd9f08d28f4f66078993065e54d45caTest
http://europepmc.org/articles/PMC8211914Test

6

Extracellular vesicles‐encapsulated let‐7i shed from bone mesenchymal stem cells suppress lung cancer via KDM3A/DCLK1/FXYD3 axis

المؤلفون: Jiefeng Liu, Yiping Liu, Yuhua Feng, Yujing Gong, Xinyu Zeng, Miao He

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Jumonji Domain-Containing Histone Demethylases, Lung Neoplasms, doublecortin‐like kinase 1, Histones, Mice, Doublecortin-Like Kinases, 0302 clinical medicine, medicine.diagnostic_test, Chemistry, Kinase, Intracellular Signaling Peptides and Proteins, Middle Aged, FXYD domain‐containing ion transport regulator 3, Lysine demethylase 3A, Neoplasm Proteins, let‐7i, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Heterografts, Molecular Medicine, Female, Original Article, Signal Transduction, Adult, Protein Serine-Threonine Kinases, Models, Biological, Extracellular Vesicles, 03 medical and health sciences, Western blot, Cell Line, Tumor, microRNA, medicine, Animals, Humans, lysine demethylase 3A, Lung cancer, Aged, Reporter gene, Mesenchymal stem cell, Membrane Proteins, Mesenchymal Stem Cells, Original Articles, Cell Biology, medicine.disease, Disease Models, Animal, MicroRNAs, lung cancer, 030104 developmental biology, bone marrow mesenchymal stem cell, Cancer research, Bone marrow

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a2c0db58225736145c804c9ceca915Test
https://doi.org/10.1111/jcmm.15866Test

7

LncRNA HOTAIR promotes endometrial fibrosis by activating TGF-β1/Smad pathway

المؤلفون: Yinmei Dai, Lingge Jin, Dan Lu, Liang Huang, Jing Chen, Juhong Liu, Ziwen Jiang, Yudi Zhang, Aihong Duan, Zhaohui Liu, Jianhong Wu

المصدر: Acta Biochimica et Biophysica Sinica. 52:1337-1347

مصطلحات موضوعية: Adult, 0301 basic medicine, Stromal cell, Primary Cell Culture, Biophysics, Apoptosis, Tissue Adhesions, Smad2 Protein, SMAD, Biochemistry, Collagen Type I, Transforming Growth Factor beta1, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, medicine, Humans, Gene silencing, Smad3 Protein, Cell Proliferation, Uterine Diseases, biology, Chemistry, HOTAIR, General Medicine, Transforming growth factor beta, medicine.disease, Actins, Up-Regulation, Antisense RNA, Collagen Type I, alpha 1 Chain, 030104 developmental biology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cell Transdifferentiation, embryonic structures, Cancer research, biology.protein, Female, RNA, Long Noncoding, Stromal Cells, Signal Transduction, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc838d48650e48592566a50d8173250aTest
https://doi.org/10.1093/abbs/gmaa120Test

8

Protein‐carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle

المؤلفون: Stewart Jeromson, Jessica R. Dent, Zhe Song, Leigh Breen, Simon W. Jones, Andrew Philp, Nathan Hodson, James Murray, D. Lee Hamilton, Mary F. O’Leary, Thomas Nicholson

المصدر: Experimental Physiology. 105:2178-2189

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Physiology, Muscle Fibers, Skeletal, Carbohydrates, P70-S6 Kinase 1, mTORC1, 030204 cardiovascular system & hematology, Cell Line, Eating, Mice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Animals, Humans, Kinase activity, Muscle, Skeletal, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, Cellular localization, Nutrition and Dietetics, biology, Myogenesis, Chemistry, TOR Serine-Threonine Kinases, fungi, Skeletal muscle, General Medicine, Middle Aged, Class III Phosphatidylinositol 3-Kinases, Endocrinology, medicine.anatomical_structure, biology.protein, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bf3f9c38af16ea81a3f00a8f595157Test
https://doi.org/10.1113/ep088805Test

9

TWIST2 and the PPAR signaling pathway are important in the progression of nonalcoholic steatohepatitis

المؤلفون: Yongqing Li, Wanshan Ma, Bingyang Zhang, Sumei Lu, Mingju Hao, Peng Gao, Yueyi Zhao, Xiaoxiao Ge, Peijun Wang, Tao Sun, Yanmei Zhang

المصدر: Lipids in Health and Disease
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Peroxisome proliferator-activated receptor, 0302 clinical medicine, Endocrinology, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Nutritional diseases. Deficiency diseases, chemistry.chemical_classification, The PPAR signaling pathway, Fatty liver, Interleukin, Nuclear Proteins, Hepatocyte steatosis, Middle Aged, High-fat diet, Disease Progression, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, Female, Signal Transduction, Adult, medicine.medical_specialty, RC620-627, Adolescent, Blotting, Western, Biology, Cell Line, 03 medical and health sciences, Young Adult, Downregulation and upregulation, Internal medicine, medicine, Animals, Humans, Transcription factor, Disease Notification, Research, Biochemistry (medical), Twist-Related Protein 1, TWIST family bHLH transcription factor 1 (TWIST1), Glucose Tolerance Test, medicine.disease, Mice, Inbred C57BL, PPAR gamma, Repressor Proteins, 030104 developmental biology, chemistry, TWIST family bHLH transcription factor 2 (TWIST2), Case-Control Studies, Hepatocytes, Steatosis, Peroxisome proliferator activated receptor gamma (PPARγ)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85e88081a917ede437b856cc542404dTest
http://europepmc.org/articles/PMC8059034Test

10

Indirubin modulates CD4+ T‐cell homeostasis via PD1/PTEN/AKT signalling pathway in immune thrombocytopenia

المؤلفون: Hai Zhou, Liang Wang, Lei Liu, Panpan Han, Jun Peng, Pengcheng Xu, Yajing Zhao, Xinguang Liu, Haoyi Wang, Ming Hou, Tianshu Yu, Tao Sun, Lizhen Li, Jihua Qiu, Shuqian Xu, Yunqi Sun, Xiaojie Wang

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, Indoles, Programmed Cell Death 1 Receptor, programmed cell‐death 1, T-Lymphocytes, Regulatory, regulatory T cells, chemistry.chemical_compound, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Tensin, Homeostasis, IL-2 receptor, biology, TOR Serine-Threonine Kinases, FOXP3, Forkhead Transcription Factors, Middle Aged, immune thrombocytopenia, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, Female, Signal Transduction, Adult, Blood Platelets, Adolescent, 03 medical and health sciences, effector T cells, Young Adult, Immune system, PTEN, Animals, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Aged, Purpura, Thrombocytopenic, Idiopathic, PTEN Phosphohydrolase, Cell Biology, Original Articles, Mice, Inbred C57BL, 030104 developmental biology, chemistry, biology.protein, Cancer research, Indirubin, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9b312ebe7cb2b11880cc6fbacd2b42Test
http://europepmc.org/articles/PMC6378207Test

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