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1
المؤلفون: Zhen Zhou, Jingying Wu, Zhi-Qiang Wang, Wei Hu, Qian Zhang, Ren-Peng Zhou
المصدر: Drug Design, Development and Therapy
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Pyridines, Drug Compounding, Administration, Oral, Biological Availability, Chinese healthy volunteers, Pharmaceutical Science, Bioequivalence, Gastroenterology, Single oral dose, Young Adult, chemistry.chemical_compound, Pharmacokinetics, Regorafenib, Internal medicine, Drug Discovery, medicine, Humans, pharmacokinetic, Adverse effect, Pharmacology, bioequivalence, Chinese population, Cross-Over Studies, Drug Design, Development and Therapy, business.industry, Phenylurea Compounds, Fasting, Healthy Volunteers, Clinical trial, Therapeutic Equivalency, phase 1, chemistry, Clinical Trial Report, Female, regorafenib, Open label, business
وصف الملف: text/html
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6504298fc9bbb068825b9624c14026fTest
https://doi.org/10.2147/dddt.s323169Test -
2
المؤلفون: Hai Ding, Ling Wang, Jiangjuan Shao, Zhen Yao, Shizhong Zheng, Anping Chen, Zili Zhang, Feng Zhang
المصدر: Autophagy. 14:2083-2103
مصطلحات موضوعية: Adult, Liver Cirrhosis, Male, 0301 basic medicine, Carcinoma, Hepatocellular, Iron, Research Paper - Basic Science, Biology, ELAV-Like Protein 1, Mice, 03 medical and health sciences, chemistry.chemical_compound, Sequestosome 1, Downregulation and upregulation, Antineoplastic Combined Chemotherapy Protocols, Autophagy, Hepatic Stellate Cells, Animals, Humans, Buthionine sulfoximine, education, Molecular Biology, Cells, Cultured, Aged, Retrospective Studies, Aged, 80 and over, education.field_of_study, Cell Death, Liver Neoplasms, Cell Biology, BECN1, Middle Aged, Sorafenib, Cell biology, Collagen Type I, alpha 1 Chain, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Hepatic stellate cell, Female, Lipid Peroxidation, Chemical and Drug Induced Liver Injury, Signal transduction, MAP1LC3B
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801aa04b684be1b5c8c5308c70da4b78Test
https://doi.org/10.1080/15548627.2018.1503146Test -
3
المؤلفون: Christopher T. Carrigan, Claire C. Whitney, Nancy E. Murphy, Marques A. Wilson, Lee M. Margolis, Adrienne Hatch-McChesney, Stefan M. Pasiakos
المصدر: Journal of the International Society of Sports Nutrition
مصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, Transcription, Genetic, High fat, AMP-Activated Protein Kinases, Muscle Development, MyoD, chemistry.chemical_compound, 0302 clinical medicine, Muscle regeneration, Phosphorylation, Cross-Over Studies, Nutrition and Dietetics, Glycogen, Myogenesis, PAX7 Transcription Factor, Endurance exercise, Carbohydrate Metabolism, Myogenin, Research Article, Adult, medicine.medical_specialty, Ergometry, Mechanistic Target of Rapamycin Complex 1, Young Adult, 03 medical and health sciences, Endurance training, Internal medicine, medicine, Humans, Aerobic exercise, RNA, Messenger, Muscle, Skeletal, Exercise, MyoD Protein, business.industry, 030229 sport sciences, High carbohydrate, 030104 developmental biology, Endocrinology, chemistry, Myogenic regulatory factors, PAX7, business, Proto-Oncogene Proteins c-akt, Biomarkers, Food Science
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b37c04c465ad8a07333448a2b285938Test
https://doi.org/10.1186/s12970-021-00455-zTest -
4
المؤلفون: Joo Youn Cho, Seung Hwan Lee, Tai Kiu Choi, Min Kyoung Kim, Kyung Sang Yu, Kyoung Soo Lim, Kyungho Jang, Jaeseong Oh, Sang-Hyuk Lee
المصدر: Drug Design, Development and Therapy
مصطلحات موضوعية: Adult, Male, Oseltamivir, viruses, Carboxylesterase 1, medicine.medical_treatment, Administration, Oral, Pharmaceutical Science, Urine, Pharmacology, Antiviral Agents, Dexamethasone, Steroid, Young Adult, 03 medical and health sciences, Carboxylesterase, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Tandem Mass Spectrometry, 030202 anesthesiology, Drug Discovery, Humans, Medicine, Original Research, Drug Design, Development and Therapy, Dose-Response Relationship, Drug, business.industry, steroid, virus diseases, carboxylesterase, Middle Aged, biochemical phenomena, metabolism, and nutrition, Prodrug, respiratory tract diseases, chemistry, 030220 oncology & carcinogenesis, ARDS, influenza, business, Chromatography, Liquid, medicine.drug
وصف الملف: text/html
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dcd86a88f86a725c655c4a18ae656fTest
https://doi.org/10.2147/dddt.s124307Test -
5
المؤلفون: Aglaya G. Iyevleva, Lev M. Berstein, Evgeny N. Imyanitov, Tatyana E Poroshina, Dmitry A Vasilyev
المصدر: Cell Cycle. 12:3681-3688
مصطلحات موضوعية: Adult, medicine.medical_specialty, Genotype, Receptors, Cell Surface, Biology, Phenformin, Impaired glucose tolerance, chemistry.chemical_compound, Insulin resistance, Sex hormone-binding globulin, Neoplasms, Report, Internal medicine, Diabetes mellitus, medicine, Humans, Hypoglycemic Agents, Molecular Biology, Alleles, Aged, Aged, 80 and over, Polymorphism, Genetic, Estradiol, Organic Cation Transporter 1, Cell Biology, Middle Aged, Scavenger Receptors, Class E, medicine.disease, Metformin, Postmenopause, Endocrinology, Diabetes Mellitus, Type 2, chemistry, biology.protein, Female, Pharmacogenetics, Developmental Biology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8216131e9073910151fac0bebbc639Test
https://doi.org/10.4161/cc.26868Test -
6CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia
المؤلفون: Lorraine J. Gudas, Andreas Hedblom, Martuza Sarwar, Nigel P. Mongan, Jenny L. Persson, Regina R. Miftakhova, Lola Anagnostaki, Anders Bredberg, Kristian B. Laursen
المصدر: Cell Cycle. 12:1251-1266
مصطلحات موضوعية: Adult, Receptors, Retinoic Acid, Cellular differentiation, Retinoic acid, Bone Marrow Cells, Tretinoin, Kaplan-Meier Estimate, Cell Fractionation, Real-Time Polymerase Chain Reaction, environment and public health, chemistry.chemical_compound, Cyclin-dependent kinase, CDC2 Protein Kinase, medicine, Humans, Phosphorylation, neoplasms, Molecular Biology, DNA Primers, Cyclin-dependent kinase 1, biology, Reverse Transcriptase Polymerase Chain Reaction, Cell Cycle, Myeloid leukemia, Cell Differentiation, Cell Biology, Flow Cytometry, medicine.disease, Immunohistochemistry, Oncogene Protein v-akt, Leukemia, Myeloid, Acute, enzymes and coenzymes (carbohydrates), Retinoic acid receptor, Leukemia, chemistry, biology.protein, Cancer research, Neoplasm Recurrence, Local, biological phenomena, cell phenomena, and immunity, Cyclin-Dependent Kinase Inhibitor p27, Developmental Biology, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7f095adaf65262f9cee24d73cd8125Test
https://doi.org/10.4161/cc.24313Test -
7
المؤلفون: Dario Roccatello, Mirella Alpa
المصدر: Drug Design, Development and Therapy
مصطلحات موضوعية: Adult, biologic agents, medicine.drug_class, Drug Resistance, Pharmaceutical Science, Familial Mediterranean fever, Case Report, anti-IL-1 treatment, Drug resistance, Biology, Antibodies, Monoclonal, Humanized, Pyrin domain, colchicine, chemistry.chemical_compound, familial Mediterranean fever, Refractory, Drug Discovery, medicine, Humans, Colchicine, Pharmacology, Antibodies, Monoclonal, Receptors, Interleukin-1, Pyrin, medicine.disease, Receptor antagonist, MEFV, Cytoskeletal Proteins, Interleukin 1 Receptor Antagonist Protein, Canakinumab, Treatment Outcome, chemistry, Immunology, Female, interleukin-1, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbc5d0a2f0ef36e17c13d1ae3bab94dTest
https://doi.org/10.2147/dddt.s69117Test