المؤلفون: Laude, K., Thuillez, C., Richard, V.

المصدر: Brazilian Journal of Medical and Biological Research. January 2001 34(1)

مصطلحات موضوعية: coronary endothelium, ischemia/reperfusion, preconditioning

الوصف: Although cardiac ischemia is usually characterized as a disease of the myocyte, it is clear that the vasculature, and especially endothelial cells, is also a major target of this pathology. Indeed, using a rat model of ischemia/reperfusion, we were able to detect severe endothelial dysfunction (assessed as a decreased response to acetylcholine) after acute or chronic reperfusion. Given the essential role of the endothelium in the regulation of vascular tone, as well as platelet and leukocyte function, such a severe dysfunction could lead to an increased risk of vasospasm, thrombosis and accelerated atherosclerosis. This dysfunction can be prevented by free radical scavengers and by exogenous nitric oxide. Endothelial dysfunction can also be prevented by preconditioning with brief periods of intermittent ischemia, thus extending to coronary endothelial cells the concept of endogenous protection previously described at the myocyte level. Experiments performed on cultured cells showed that the endothelial protection induced by free radical scavengers or by preconditioning was due to a lesser expression of endothelial adhesion molecules such as intercellular adhesion molecule-1, leading to a lesser adhesion of neutrophils to endothelial cells. Identification of the mechanisms of this protection may lead to the development of new strategies aimed at protecting the vasculature in ischemic heart diseases.

وصف الملف: text/html

الوصول الحر: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000100001Test

المؤلفون: Michot, F., Launois, B., Bertrand, D., Bringer, J., Degos, L., Olie, J.-P., Thuillez, C.

المصدر: Bulletin de l'Académie Nationale de Médecine ; volume 203, issue 3-4, page 109-121 ; ISSN 0001-4079

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.banm.2019.02.011Test
https://api.elsevier.com/content/article/PII:S0001407919300767?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0001407919300767?httpAccept=text/plainTest

المؤلفون: Gwladys, N., Putzolu, J., Bélorgey, C., Thuillez, C., Grande, M.

المصدر: Value in Health ; volume 22, page S799 ; ISSN 1098-3015

مصطلحات موضوعية: Public Health, Environmental and Occupational Health, Health Policy

الإتاحة: https://doi.org/10.1016/j.jval.2019.09.2123Test
https://api.elsevier.com/content/article/PII:S1098301519345012?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1098301519345012?httpAccept=text/plainTest

المؤلفون: Mazin, N., Fernandez, J., Busin, C., Bélorgey, C., Thuillez, C., Grande, M.

المصدر: Value in Health ; volume 22, page S724 ; ISSN 1098-3015

مصطلحات موضوعية: Public Health, Environmental and Occupational Health, Health Policy

الإتاحة: https://doi.org/10.1016/j.jval.2019.09.1712Test
https://api.elsevier.com/content/article/PII:S1098301519340902?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1098301519340902?httpAccept=text/plainTest

المؤلفون: Cruickshank J.K., Wilkinson I., Roman M.J., Devereux R.B., Teal V., Townsend R., Vermeersch S., Herbert A., Laurent S., Boutouyrie P., Shimada K., Kario K., Miyashita H., Eguchi K., Kohara K., Tabara Y., Imai Y., Ito S., Hashimoto J., Uchiba K., Suzuki H., Takenaka T., Takazawa K., Kino M., Yamashina A., Tomiyama H., Dohi Y., Takase H., Jouven X., Empana J.P., Pannier B., Thomas F., Prescott E., Janner J., McEniery C., Cockcroft J., Rietzschel E.R., Van Bortel L., De Buyzere M.L., Segers P., Gillebert T.C., Wang J.-G., Li Y., Lazar J., Salciccioli L., Cunha P., Oliveira P., Cotter J., Vila I., Sousa N., Chirinos J., Medina-Lezama J., Weber T., Rammer M., O'Rourke M.F., Bernd E., Lassnig E., Porodko M., Ammer M., Wassertheurer S., Adji A., Rosenkranz S., Punzengruber C., Kvas E., Dufouil C., Ferreira I., Twisk J.W., Smulders Y.M., Van De Laar R.J., Van Kallen C.J., Van Greevenbroek M.M., Schalkwijk C.G., Vlachopoulos C., Aznaouridis C., Terentes-Printzios D., Tzourio C., Nijpels G., Dekker J.M., Stehouwer C.D.A., Xaplanteris P., Stefanadis C., Schutte A.E., Fourie C.M.T., Van Rooyen J.M., Mahmud A., Feely J., Ghiadoni L., Stea F., Bruno R.M., Cartoni G., Armenia S., Taddei S., Seidlerova J., Vanek J., Filipovsky J., Mayer O., Jr., Lind L., Soveri I., Fellström B., Zilmer M., Cavallini M.C., Pini R., Di Bari M., Marchionni N., Masotti G., Schillaci G., Pucci G., Battista F., Settimi L., Crilly M.A., Kumar V., Clark H.J., Scott N.W., Macdonald A.G., Williams D.J., Hillis G.S., Lee A.J., De Vries A., Small G.R., Zanchetti A., Bilo G., Taurino C., McClure J.D., Schneider M.P., Kawecka-Jaszcz K., Stolarz-Skrzypek K., Klima L., Staessen J.A., Kuznetsova T., Redon J., Martinez F., Rosei E.A., Melander O., Zannad F., Rossignol P., Collin C., Lonati L., Dominiczak A.F., O'Rourke M., Petrak O., Štrauch B., Rosa J., Widimsky J., Hu J., Barinova I.V., Seredenina E.M., Pipingas A., Pase M.P., Grima N.A., Stough C., Harris E., Sellick L., Macpherson H., Pascualab J.M., Rodilla E., Costa J.A., Simon T., Delles C., Dymott J.A., Neisius U., Carty D.M., Fesler P., Muiesan M.L., Salvettia M., Paini A., Tisler A., Zofi, Nemeth K., Marton A., El Haj Othmane T., Cseprekal O., Studinger P., Ibrahim N.N.I.N., Rasool A.H.G., Rahman A.R.A., Wong A.R., Protogerou A.D., Papaioannou T.G., Sfikakis P.P., Fu Y., Zhao L., Li N., Jiang X., Demirci M.S., Gungor O., Orlova I.A., Blankova Z.N., Ageev F.T., Bellien J., Iacob M., Thuillez C., Joannides, Erglis A., Mintale I., Latkovskis G., Berzina M., Zabunova M., Krallisa A., Smulyan H., Safar M., Zhadan A., Tselukyo V., Bregvadze T., Aydin A., Von Kodolitsch Y., Ok E.

مصطلحات موضوعية: Aged, Adult, Aorta, Arteries, Arteriosclerosis, Blood pressure, Central pressure, Humans, Pulse

الوصف: PubMed ID: 25112663 ; Aims: Estimated central systolic blood pressure (cSBP) and amplification (Brachial SBP-cSBP) are non-invasive measures potentially prognostic of cardiovascular (CV) disease. No worldwide, multiple-device reference values are available. We aimed to establish reference values for a worldwide general population standardizing between the different available methods of measurement. How these values were significantly altered by cardiovascular risk factors (CVRFs) was then investigated. Methods and results: Existing data from population surveys and clinical trials were combined, whether published or not. Reference values of cSBP and amplification were calculatedas percentiles for 'Normal' (no CVRFs) and 'Reference' (any CVRFs) populations. We included 45 436 subjects out of 82 930 that were gathered from 77 studies of 53 centres. Included subjects were apparently healthy, not treated for hypertension or dyslipidaemia, and free from overt CV disease and diabetes. Values of cSBP and amplification were stratified by brachial blood pressure categories and age decade in turn, both being stratifiedbysex. Amplification decreased with age and more so in males than in females. Sex was the most powerful factor associated with amplification with 6.6 mmHg (5.8-7.4) higher amplification in males than in females. Amplification was marginally but significantly influenced by CVRFs, with smoking and dyslipidaemia decreasing amplification, but increased with increasing levels of blood glucose. Conclusion: Typical values of cSBP and amplification in a healthy population and a population free of traditional CVRFs are now available according to age, sex, and brachial BP, providing values included from different devices with a wide geographical representation. Amplification is significantly influenced by CVRFs, but differently in men and women. © 2014 Published on behalf of the European Society of Cardiology.

العلاقة: Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; European Heart Journal; https://hdl.handle.net/11454/17406Test; https://doi.org/10.1093/eurheartj/ehu293Test; 35; 44; 3122; 3133

الإتاحة: https://doi.org/10.1093/eurheartj/ehu293Test
https://hdl.handle.net/11454/17406Test

المؤلفون: Herbert A., Cruickshank J.K., Laurent S., Boutouyrie P., Shimada K., Kario K., Miyashita H., Eguchi K., Kohara K., Tabara Y., Imai Y., Ito S., Hashimoto J., Uchiba K., Suzuki H., Takenaka T., Takazawa K., Kino M., Yamashina A., Tomiyama H., Dohi Y., Takase H., Jouven X., Empana J.P., Pannier B., Thomas F., Prescott E., Janner J., McEniery C., Cockcroft J., Wilkinson I., Roman M.J., Devereux R.B., Teal V., Townsend R., Vermeersch S., Rietzschel E.R., Van Bortel L., De Buyzere M.L., Segers P., Gillebert T.C., Wang J.-G., Li Y., Lazar J., Salciccioli L., Cunha P., Oliveira P., Cotter J., Vila I., Sousa N., Chirinos J., Medina-Lezama J., Weber T., Rammer M., O'Rourke M.F., Bernd E., Lassnig E., Porodko M., Ammer M., Wassertheurer S., Adji A., Rosenkranz S., Punzengruber C., Kvas E., Dufouil C., Tzourio C., Nijpels G., Dekker J.M., Stehouwer C.D.A., Ferreira I., Twisk J.W., Smulders Y.M., Van De Laar R.J., Van Kallen C.J., Van Greevenbroek M.M., Schalkwijk C.G., Vlachopoulos C., Aznaouridis C., Terentes-Printzios D., Xaplanteris P., Stefanadis C., Schutte A.E., Fourie C.M.T., Van Rooyen J.M., Mahmud A., Feely J., Ghiadoni L., Stea F., Bruno R.M., Cartoni G., Armenia S., Taddei S., Seidlerova J., Vanek J., Filipovsky J., Mayer O., Jr., Lind L., Soveri I., Fellström B., Zilmer M., Cavallini M.C., Pini R., Di Bari M., Marchionni N., Masotti G., Schillaci G., Pucci G., Battista F., Settimi L., Crilly M.A., Kumar V., Clark H.J., Scott N.W., Macdonald A.G., Williams D.J., Hillis G.S., Lee A.J., De Vries A., Small G.R., Zanchetti A., Bilo G., Taurino C., McClure J.D., Schneider M.P., Kawecka-Jaszcz K., Stolarz-Skrzypek K., Klima L., Staessen J.A., Kuznetsova T., Redon J., Martinez F., Rosei E.A., Melander O., Zannad F., Rossignol P., Collin C., Lonati L., Dominiczak A.F., O'Rourke M., Petrak O., Štrauch B., Rosa J., Widimsky J., Pipingas A., Pase M.P., Grima N.A., Stough C., Harris E., Sellick L., Macpherson H., Pascualab J.M., Rodilla E., Costa J.A., Simon T., Delles C., Dymott J.A., Neisius U., Carty D.M., Fesler P., Muiesan M.L., Salvettia M., Paini A., Tisler A., Zofi, Nemeth K., Marton A., El Haj Othmane T., Cseprekal O., Studinger P., Ibrahim N.N.I.N., Rasool A.H.G., Rahman A.R.A., Wong A.R., Protogerou A.D., Papaioannou T.G., Sfikakis P.P., Fu Y., Hu J., Zhao L., Li N., Jiang X., Ok E., Demirci M.S., Gungor O., Orlova I.A., Blankova Z.N., Seredenina E.M., Ageev F.T., Barinova I.V., Bellien J., Iacob M., Thuillez C., Joannides, Erglis A., Mintale I., Latkovskis G., Berzina M., Zabunova M., Krallisa A., Smulyan H., Safar M., Zhadan A., Tselukyo V., Bregvadze T., Aydin A., Von Kodolitsch Y.

المساهمون: Ege Üniversitesi

مصطلحات موضوعية: Adult, Aged, Aorta, Arteries, Arteriosclerosis, Blood pressure, Central pressure, Humans, Pulse

الوصف: PubMed ID: 25112663 ; Aims: Estimated central systolic blood pressure (cSBP) and amplification (Brachial SBP-cSBP) are non-invasive measures potentially prognostic of cardiovascular (CV) disease. No worldwide, multiple-device reference values are available. We aimed to establish reference values for a worldwide general population standardizing between the different available methods of measurement. How these values were significantly altered by cardiovascular risk factors (CVRFs) was then investigated. Methods and results: Existing data from population surveys and clinical trials were combined, whether published or not. Reference values of cSBP and amplification were calculatedas percentiles for 'Normal' (no CVRFs) and 'Reference' (any CVRFs) populations. We included 45 436 subjects out of 82 930 that were gathered from 77 studies of 53 centres. Included subjects were apparently healthy, not treated for hypertension or dyslipidaemia, and free from overt CV disease and diabetes. Values of cSBP and amplification were stratified by brachial blood pressure categories and age decade in turn, both being stratifiedbysex. Amplification decreased with age and more so in males than in females. Sex was the most powerful factor associated with amplification with 6.6 mmHg (5.8-7.4) higher amplification in males than in females. Amplification was marginally but significantly influenced by CVRFs, with smoking and dyslipidaemia decreasing amplification, but increased with increasing levels of blood glucose. Conclusion: Typical values of cSBP and amplification in a healthy population and a population free of traditional CVRFs are now available according to age, sex, and brachial BP, providing values included from different devices with a wide geographical representation. Amplification is significantly influenced by CVRFs, but differently in men and women. © 2014 Published on behalf of the European Society of Cardiology.

العلاقة: Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; European Heart Journal; https://doi.org/10.1093/eurheartj/ehu293Test; https://hdl.handle.net/11454/17406Test; 35; 44; 3122; 3133

الإتاحة: https://doi.org/10.1093/eurheartj/ehu293Test
https://hdl.handle.net/11454/17406Test

المؤلفون: Bellien, J., Freguin-Bouilland, C., Joannides, R., Hanoy, M., Remy-Jouet, I., Monteil, C., Iacob, M., Martin, L., Renet, S., Vendeville, C., Godin, M., Thuillez, C., Le Roy, F.

المصدر: Nephrology Dialysis Transplantation ; volume 29, issue 2, page 414-422 ; ISSN 0931-0509 1460-2385

مصطلحات موضوعية: Transplantation, Nephrology

الإتاحة: https://doi.org/10.1093/ndt/gft448Test
http://academic.oup.com/ndt/article-pdf/29/2/414/7640558/gft448.pdfTest

المؤلفون: Harouki, N., Nicol, L., Merabet, N., Henry, J. P., Gluais, P., Richard, V., Roussel, J., Thuillez, C., Mulder, P.

المصدر: European Heart Journal ; volume 34, issue suppl 1, page P5532-P5532 ; ISSN 0195-668X 1522-9645

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

الإتاحة: https://doi.org/10.1093/eurheartj/eht310.p5532Test

المؤلفون: Joannidès, R., Monteil, C., de Ligny, B.H., Westeel, P.F., Iacob, M., Thervet, E., Barbier, S., Bellien, J., Lebranchu, Y., Seguin, S.G., Thuillez, C., Godin, M., Etienne, I.

المصدر: American Journal of Transplantation ; volume 11, issue 11, page 2414-2422 ; ISSN 1600-6135

مصطلحات موضوعية: Pharmacology (medical), Transplantation, Immunology and Allergy

الإتاحة: https://doi.org/10.1111/j.1600-6143.2011.03697.xTest
https://api.elsevier.com/content/article/PII:S1600613522281581?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1600613522281581?httpAccept=text/plainTest

المؤلفون: Vergeade, A., Mulder, P., Dehaudt, C., Fortin, D., Ventura-Clapier, R., Thuillez, C., Monteil, C.

المصدر: Archives of Cardiovascular Diseases ; volume 102, page S31 ; ISSN 1875-2136

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, General Medicine

الإتاحة: https://doi.org/10.1016/s1875-2136Test(09)72200-4
https://api.elsevier.com/content/article/PII:S1875213609722004?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1875213609722004?httpAccept=text/plainTest