المؤلفون: Start, Alex O., Ryan, Gillian A., Cathcart, Barbra, Geraghty, Jennifer, Adams, Niamh, Colleran, Gabrielle, Vavasseur, Claudine, Caird, John, Murray, Dylan, Walsh, Jennifer M.

المساهمون: University College Dublin

المصدر: Irish Journal of Medical Science (1971 -) ; volume 192, issue 6, page 2881-2885 ; ISSN 0021-1265 1863-4362

مصطلحات موضوعية: General Medicine

الوصف: We present the case of a pregnant 32-year-old woman who presented with a giant fetal facial tumour at 22 weeks. The mass, initially 4 × 3.5 × 3 cm in size, was largely cystic with a small solid component. It subsequently increased to 9 × 9 × 10 cm. Significant compression effects on the fetal orbit, temple and infratemporal fossa, with potential compression of the optic nerve, were noted on ultrasound and MRI. The cyst required drainage twice in the pregnancy: firstly to reduce the compression effects and secondly to facilitate caesarean delivery. Postnatally, the baby had significant compression and displacement of the craniofacial skeleton from the mass effect. Postnatal histology revealed a diagnosis of a teratoma. This case highlights the complexities and challenges surrounding the diagnosis and management of a giant fetal facial tumour.

الإتاحة: https://doi.org/10.1007/s11845-023-03344-3Test

المؤلفون: Mui, Olivia O.T., Murray, Daniel B., Walsh, Bill, Crimmins, Darach W., Caird, John D.

المساهمون: Royal College of Surgeons in Ireland

المصدر: Child's Nervous System ; volume 39, issue 4, page 1051-1058 ; ISSN 0256-7040 1433-0350

مصطلحات موضوعية: Neurology (clinical), General Medicine, Pediatrics, Perinatology and Child Health

الوصف: Introduction The primary objective of neurosurgical management of malignant gliomas is maximal safe resection of the tumour. One of the main obstacles in achieving this is the ability to accurately discriminate between tumour edges and the surrounding healthy brain tissue. The use of fluorescence-guided surgery utilising 5-aminolevulinic acid (5-ALA), first introduced more than 20 years ago, has become an invaluable adjunct in high-grade glioma surgery in adults. However, as 5-ALA is not licensed for use in paediatric patients, the safety profile for such use remains undetermined. Case report We describe the case of a 4-year-old boy who underwent 5-ALA-guided resection of a fourth ventricle anaplastic ependymoma. Although complete resection was achieved and the patient awoke from surgery well with no neurological deficits, the patient developed acute transaminitis, anaemia, thrombocytopaenia and coagulopathy postoperatively. The patient had a sudden neurological deterioration on postoperative day 2; imaging revealed that he had suffered a spontaneous right frontal intracerebral haemorrhage. The patient returned to theatre for surgical decompression and evacuation of the haematoma, and ultimately went on to make a full recovery. Conclusion The use of 5-ALA in paediatric patients can be helpful in maximising surgical resection, but the associated safety profile remains undefined. Further research is urgently warranted in order to characterise the efficacy and risk of the use of 5-ALA in the paediatric population.

الإتاحة: https://doi.org/10.1007/s00381-023-05846-yTest

المؤلفون: Caird, John

الوصول الحر: https://www.europeana.eu/item/362/item_LTKU4PG4S665IUSPV2YPWTFLTTEFSNAC?utm_source=api&utm_medium=api&utm_campaign=YuvuWBeCaTest

المؤلفون: O’Halloran, Philip J., Cleary, Anna, Cryan, Jane B., Beausang, Alan, Brett, Francesca M., Caird, John

المصدر: British Journal of Neurosurgery ; volume 36, issue 2, page 236-240 ; ISSN 0268-8697 1360-046X

الإتاحة: https://doi.org/10.1080/02688697.2021.1918327Test

المؤلفون: Start, Alex O., Ryan, Gillian, McParland, Peter, Crimmins, Darach, Caird, John, Mcauliffe, Fionnuala M.

المصدر: American Journal of Obstetrics and Gynecology ; volume 224, issue 2, page S275 ; ISSN 0002-9378

مصطلحات موضوعية: Obstetrics and Gynecology

الإتاحة: https://doi.org/10.1016/j.ajog.2020.12.452Test
https://api.elsevier.com/content/article/PII:S0002937820318287?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0002937820318287?httpAccept=text/plainTest

المؤلفون: Walsh, Aoiibhinn, Mernagh, Angela, Caird, John, Crimmins, Darach, Ringholz, Fiona, Williamson, Michael, Healy, Fiona

المصدر: Abstracts

الإتاحة: https://doi.org/10.1136/archdischild-2019-epa.339Test

المؤلفون: Tan, Joy, Caird, John, Nicholson, Alf

المصدر: Abstracts

الإتاحة: https://doi.org/10.1136/archdischild-2019-epa.190Test

المؤلفون: Trench, Luke, Bracken, Shirley, McInerney, Niall, Caird, John, Murray, Dylan J

المصدر: Abstracts

الإتاحة: https://doi.org/10.1136/archdischild-2019-epa.7Test

المؤلفون: O’Sullivan, Hugh, Bracken, Shirley, Caird, John, Kyne, Louise, Murray, Dylan, Doyle, Jodie

المصدر: Abstracts

الإتاحة: https://doi.org/10.1136/archdischild-2019-epa.76Test

المؤلفون: Howard, Alan, Krishnan, Vinaithan, Lane, Gerard, Caird, John

مصطلحات موضوعية: Swing shift: innovations in emergency medicine

الوصف: The practice of trepanning (referred to today as a craniotomy) dates back to the Neolithic period. Reasons for drilling a hole through the skull evolved from releasing evil spirits and curing insanity to practical management of head injuries in ancient Greece and Rome. Today, craniotomy or drilling a burr hole through the skull is very much the purview of the neurosurgeon. Yet one could argue that the procedure itself is more ‘bone surgery’ than ‘brain surgery’. Nevertheless, despite the fact that head injury is a common presentation at district general hospitals and traumatic extra-axial haemorrhages are encountered often, the straightforward skillset required to drill a burr hole as a pretransfer, temporising, life-saving measure is seldom taught and has never gained traction. What we advocate in this article is the adaptation and novel application of an old, tried and tested technique in new hands. The critical pathophysiological turning point of any expanding extra-axial haemorrhage is the inflection point on the volume/Intracranial pressure (ICP) curve beyond which compensation is impossible. The subsequent rising ICP initiates a predictable continuum of clinical signs signalling progressive herniation. There are few emergencies as time-critical as a patient with an isolated, expanding extradural haemorrhage embarking on a trajectory of rostrocaudal deterioration and inevitable death. In many cases, the tragedy is compounded by the knowledge that such a patient probably has a healthy underlying brain, often evidenced by a lucid period after trauma. Our emergency department is attached to a small 300-bed District General Hospital (DGH) on the rural North West coast of Ireland. We are 262 km distant by road from a national neurosciences department that can, at best, be reached in 2 hours and 30 min. Quality improvement review of years of dismal outcomes in patients such as those described earlier with potentially remediable pathology prompted research and development of the skillset we are now able to offer, ...

وصف الملف: text/html

العلاقة: http://emj.bmj.com/cgi/content/short/37/3/151Test; http://dx.doi.org/10.1136/emermed-2019-208943Test

الإتاحة: https://doi.org/10.1136/emermed-2019-208943Test
http://emj.bmj.com/cgi/content/short/37/3/151Test