المؤلفون: Yoshio Sakai, Taro Yamashita, Yasuhito Imai, Oto Inoue, Kazuhide Higuchi, Tuyen Thuy Bich Ho, Soichiro Usui, Shuichi Kaneko, Yusuke Tsuchimoto, Akira Asai, Kuniaki Arai, Tatsuya Yamashita, Takashi Wada, Kenichi Yoshimura, Masao Honda, Shinya Fukunishi, Shinichiro Takashima, Kenichi Harada, Eishiro Mizukoshi, Toshinori Murayama, Masayuki Takamura, Alessandro Nasti, Akihiro Seki, Kazunori Kawaguchi

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 18, Iss, Pp 97-101 (2021)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), medicine.medical_specialty, Cirrhosis, MSCs, mesenchymal stem cells, Adipose tissue dissociation device, NASH, non-alcoholic steatohepatitis, Biomedical Engineering, Adipose tissue, Gastroenterology, Biomaterials, Cell therapy, 03 medical and health sciences, R5-920, 0302 clinical medicine, Internal medicine, Fatty liver diseases, medicine, Adipose tissue-derived regenerative (stem) cells, Non-alcoholic steatohepatitis, QH573-671, business.industry, Fatty liver, Conductible, ADRCs, adipose tissue derived regenerative (stem) cells, medicine.disease, Clinical trial, 030104 developmental biology, PMDA, Japan Pharmaceuticals and Medical Devices Agency, Liver cirrhosis, Original Article, NAFLD, nonalcoholic fatty liver disease, Steatohepatitis, Stem cell, Cytology, business, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498cb8601adedc4119b89a161cd23e11Test
http://europepmc.org/articles/PMC8165289Test

المؤلفون: Pirouz Samidoust, Mohammad Taghi Ashoobi, R. Navid Talemi, M.S. Esmaeili Delshad, K. Mojtahedi, Aryan Samidoust, S. Jahangiri

المصدر: New Microbes and New Infections, Vol 44, Iss, Pp 100935-(2021)
New Microbes and New Infections

مصطلحات موضوعية: medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), medicine.medical_treatment, AST, aspartate aminotransferase, Disease, Infectious and parasitic diseases, RC109-216, Liver transplantation, Iran, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Microbiology, ACE2, angiotensin-converting enzyme-2, Internal medicine, medicine, HDL, High-density lipoprotein, liver transplant recipients, DBIL, direct bilirubin, CTscan, computed tomography scan, CDC, Centers for Disease Control, In patient, TBIL, total bilirubin, NSAIDs, nonsteroidal anti-inflammatory drugs, HBV, Hepatitis B, NASH, Non-alcoholic steatohepatitis, Liver injury, liver transplantation, business.industry, SARS-CoV-2, Incidence (epidemiology), COVID-19, Retrospective cohort study, medicine.disease, PSC, primary sclerosing cholangitis, Infectious Diseases, Original Article, SD, standard deviation, business, TBIL

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990cdcfd9e698bf3a0e2b7d10e9e6b75Test
http://www.sciencedirect.com/science/article/pii/S2052297521000998Test

المؤلفون: Hans-Peter Hammes, Elena Heidenreich, Peter P. Nawroth, Martina U. Muckenthaler, Sandro Altamura, Thomas Fleming, Andrea Schlotterer, Katja Müdder, Ruiyue Qiu

المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101235-(2021)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, DR, diabetic retinopathy, Hepcidin, medicine.disease_cause, Mice, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, MetS, Metabolic Syndrome, Internal medicine, biology, Fpn, Ferroportin, Fatty liver, Liver, DIOS, dysmetabolic iron overload syndrome, CRP, C-reactive protein, Receptors, Leptin, HH, hereditary hemochromatosis, Original Article, IRP, Iron Regulatory Protein, medicine.medical_specialty, Iron Overload, Iron, 030209 endocrinology & metabolism, Mice, Transgenic, IR, Insulin Resistance, SEM, standard error of the mean, 03 medical and health sciences, Insulin resistance, ROS, reactive oxygen species, NASH, Non Alcoholic Steatohepatitis, NAFLD, medicine, Animals, Humans, Molecular Biology, business.industry, NTBI, Non Transferrin Bound Iron, Cell Biology, medicine.disease, RC31-1245, IRS1, Db/db Mouse, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, NAFLD, Non Alcoholic Fatty Liver Disease, Lipid Peroxidation, Steatosis, Metabolic syndrome, business, Oxidative stress, IRE, Iron Responsive Element, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ad7abfa625d87337f2502f8e59462Test
http://www.sciencedirect.com/science/article/pii/S2212877821000806Test

المؤلفون: Carrie E. McCurdy, Kenneth N. Maclean, Paul Kievit, Bryan C. Bergman, Rachel C. Janssen, Peter R. Baker, Christopher M. Mulligan, Tyler Dean, Diana L. Takahashi, Travis Nemkov, Kjersti Aagaard, Hua Jiang, Stephanie R. Wesolowski, Angelo D'Alessandro, Jacob E. Friedman

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 25-41 (2018)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Steatosis, VIP, variable importance in projection, Hypoxemia, AUC, area under the curve, PC, phosphatidylcholine, 0302 clinical medicine, WSD, Western-style diet, Non-alcoholic Fatty Liver Disease, Pregnancy, Fetal programming, Hyperlipidemia, DAG, diacylglyceride, VLDL, very low-density lipoprotein, Hypoxia, 2. Zero hunger, TG, triglyceride, NEFA, non-esterified fatty acid, NHP, non-human primate, Fatty liver, 3. Good health, Liver, Lipotoxicity, CON, control, OB-WSD, Western-style diet induced obesity group, IV-GTT, intravenous glucose tolerance test, Prenatal Exposure Delayed Effects, Original Article, Female, Diet, Healthy, PLS-DA, partial least squares discriminant analysis, TCA, tricarboxylic acid cycle, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, medicine.medical_specialty, Offspring, NASH, non-alcoholic steatohepatitis, Citric Acid Cycle, Metabolomic, 030209 endocrinology & metabolism, DNL, de novo lipogenesis, TBARs, thiobarbituric acid reactive substances, OB-DR, diet reversal group, 03 medical and health sciences, Fetus, Internal medicine, medicine, TBARS, Animals, Obesity, AA, amino acid, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Gluconeogenesis, Maternal Nutritional Physiological Phenomena, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, Diet, Western, Macaca, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06dccd8288a52f01636dbe7fd72ba0fTest
https://doi.org/10.1016/j.molmet.2018.09.008Test

المؤلفون: Yanyong Xu, Kavita Jadhav, Yingdong Zhu, Yuan-Yuan Li, Takhar Kasumov, Jiesi Xu, Yang Xu, Luciano Adorini, Yoon Kwang Lee, Yanqiao Zhang, Liya Yin

المصدر: Molecular Metabolism, Vol 9, Iss, Pp 131-140 (2018)
Molecular Metabolism

مصطلحات موضوعية: Male, 0301 basic medicine, Col1α1, collagen type 1 α1, NS, not significant, Receptors, Cytoplasmic and Nuclear, PPARγ, peroxisome proliferation-activated receptor γ, Receptors, G-Protein-Coupled, Mice, IL-1β, interleukin 1β, SHP, small heterodimer partner, α-Sma, alpha smooth muscle actin (α-Sma), HFD, high fat diet, Non-alcoholic Fatty Liver Disease, Tgfβ, transforming growth factor β, Receptor, TG, triglyceride, Bile acid, Chemistry, TGR5, GLP-1, glucagon-like peptide-1, Hep G2 Cells, Peroxisome, G protein-coupled bile acid receptor, 3. Good health, TNFα, tumor necrosis factor α, Pck1, phosphoenoylpyruvate carboxylase 1, TGR5, G protein coupled bile acid receptor (GPBAP), Lipogenesis, BA, bile acid, G6pc, glucose 6-phosphatase, Small heterodimer partner, Original Article, Agonist, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, lcsh:Internal medicine, Timp1, tissue inhibitor of metalloproteinase 1, medicine.drug_class, NASH, non-alcoholic steatohepatitis, Hypercholesterolemia, Diet, High-Fat, Bile Acids and Salts, 03 medical and health sciences, FXR, farnesoid X receptor, Farnesoid X receptor, NAFLD, Internal medicine, medicine, Animals, Humans, Obesity, lcsh:RC31-1245, Molecular Biology, CEBPα, CCAAT/enhancer-binding protein α, DIO, diet-induced obesity, Cell Biology, Atherosclerosis, Mice, Inbred C57BL, BAT, brown adipose tissue, 030104 developmental biology, Endocrinology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6f686d41c1a501b1cae42176973abbTest
http://www.sciencedirect.com/science/article/pii/S2212877817309195Test

المؤلفون: Adam J. Rauckhorst, Xiaorong Fu, Katherine N. Gibson-Corley, Alvin D. Pewa, Ryan D. Sheldon, Eric B. Taylor, James E. Cox, Charlotte R. Feddersen, Shawn C. Burgess, Adam J. Dupuy, Lawrence R. Gray

المصدر: Molecular Metabolism, Vol 6, Iss 11, Pp 1468-1479 (2017)
Molecular Metabolism

مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, Mitochondria, Liver, Mitochondrion, Mitochondrial Membrane Transport Proteins, Mice, 0302 clinical medicine, HFD, high fat diet, Fibrosis, immune system diseases, Pyruvic Acid, digestive, oral, and skin physiology, Diabetes, Mitochondria, HOMA-IR, homeostatic model assessment of insulin resistance, medicine.anatomical_structure, Liver, Mitochondrial matrix, 030220 oncology & carcinogenesis, Hepatocyte, Original Article, MPC, mitochondrial pyruvate carrier, TCA, tricarboxylic acid cycle, Monocarboxylic Acid Transporters, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, lcsh:Internal medicine, NASH, non-alcoholic steatohepatitis, Anion Transport Proteins, Citric Acid Cycle, T2D, type 2 diabetes, Biology, Diet, High-Fat, Mitochondrial pyruvate carrier (MPC), 03 medical and health sciences, Internal medicine, medicine, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, ITT, insulin tolerance test, Inflammation, NCD, normal chow diet, Gluconeogenesis, Membrane Transport Proteins, nutritional and metabolic diseases, Cell Biology, Metabolism, medicine.disease, Citric acid cycle, Disease Models, Animal, Cytosol, Glucose, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Hyperglycemia, Hepatocytes, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80260421dd9726225c6f9a3cac3cf9faTest
http://www.sciencedirect.com/science/article/pii/S2212877817306828Test

المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459Test

المؤلفون: Elisabeth D. Galsgaard, Henrik D. Pedersen, Berit Østergaard Christoffersen, Merete Fredholm, Markus Latta, Dorte Holst, Susanna Cirera

المصدر: Journal of Clinical and Experimental Hepatology
Pedersen, H D, Galsgaard, E D, Christoffersen, B, Cirera, S, Holst, D, Fredholm, M & Latta, M 2020, ' NASH-inducing Diets in Göttingen Minipigs ', Journal of Clinical and Experimental Hepatology, vol. 10, no. 3, pp. 211-221 . https://doi.org/10.1016/j.jceh.2019.09.004Test

مصطلحات موضوعية: medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Porcine, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, GLDH, glutamate dehydrogenase, Choline, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, AST, aspartate transaminase, Internal medicine, Fatty liver, FFC, high-fat, fructose, cholesterol, Medicine, Animal model, amino acid defined high-fat diet (-S, with sucrose, Sirius Red, Hepatology, EDTA, ethylenediaminetetraacetic acid, ALP, alkaline phosphatase, business.industry, Cholesterol, GGT, gamma-glutamyltransferase, HE, hematoxylin and eosin, Fructose, medicine.disease, Endocrinology, chemistry, CD45, cluster of differentiation 45, 030220 oncology & carcinogenesis, Hepatic stellate cell, 030211 gastroenterology & hepatology, Original Article, F, with fructose), SMA, smooth muscle actin, CDAHFD, choline-deficient, Steatosis, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05e1f5726ee082ed2c5c2d742ea87d1Test
https://pubmed.ncbi.nlm.nih.gov/32405177Test

المؤلفون: Xuemei Wang, Wei Kong, Yuanyuan Pang, Lulu Sun, Huiying Liu, Bo Liu, Min Ye, Qing Wu, George Liu, Changtao Jiang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 702-710 (2019)

مصطلحات موضوعية: eWAT, epididymal white adipose tissue, Metabolic disorders, White adipose tissue, Gut flora, UPLC–MS/MS, ultra performance liquid chromatography–tandem mass spectrometry, 0302 clinical medicine, HFD, high fat diet, AST, aspartate transaminase, GCA, glycocholic acid, VLDL, very low-density lipoprotein, TβMCA, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, CAPE, caffeic acid phenethyl ester, TβMCA, tauro-β-muricholic acid, 0303 health sciences, CA, cholic acid, GCDCA, glycochenodeoxycholic acid, CYP7B1, biology, Bile acid, Chemistry, sWAT, subcutaneous white adipose tissue, FGF15/19, fibroblast growth factor 15/19, TG, triglycerides, CETP, cholesterol ester transfer protein, CYP7A1, cytochrome P450 family 7 subfamily A member 1, FXR, 030220 oncology & carcinogenesis, GTT, glucose tolerance test, BSH, bile acid hydrolase, CYP7B1, cytochrome P450 family 7 subfamily B member 1, medicine.medical_specialty, Original article, NAFLD, non-alcoholic fatty liver disease, PBA/SBA, primary bile acids to secondary bile acids, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TCA, taurocholic acid, Hamster, ALT, alanine amino-transferase, CYP8B1, cytochrome P450 family 8 subfamily B member 1, T2D, type 2 diabetes, Gut microbiota, AUC, area under curve, digestive system, CYP27A1, cytochrome P450 family 27 subfamily A member 1, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, 03 medical and health sciences, Insulin resistance, FXR, farnesoid X receptor, Internal medicine, medicine, ApoB, apolipoprotein B, 030304 developmental biology, ITT, insulin tolerance test, BAs, bile acids, lcsh:RM1-950, medicine.disease, biology.organism_classification, TC, total cholesterol, lcsh:Therapeutics. Pharmacology, Endocrinology, DCA, deoxycholic acid, H&E, hematoxylin and eosin, Farnesoid X receptor, Steatosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc312ddccc0b191b5f0414f6cd3240aTest
https://pubmed.ncbi.nlm.nih.gov/31384531Test

المؤلفون: Alexandra K. Leamy, Jamey D. Young, Robert A. Egnatchik, Masakazu Shiota, David A. Jacobson

المصدر: Molecular Metabolism

مصطلحات موضوعية: NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, SERCA, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, chemistry.chemical_element, Biology, Calcium, Mitochondrion, medicine.disease_cause, PA, palmitate, Calcium in biology, PI, propidium iodide, 03 medical and health sciences, chemistry.chemical_compound, H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate, ROS, reactive oxygen species, 0302 clinical medicine, BAPTA, Fatty liver, Internal medicine, CAC, citric acid cycle, FFA, free fatty acid, MUFA, monounsaturated fatty acid, medicine, Molecular Biology, MFA, metabolic flux analysis, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, APE, atom percent enrichment, Metabolic flux analysis, Cell Biology, SERCA, sarcoplasmic-endoplasmic reticulum calcium ATPase, 3. Good health, Endocrinology, chemistry, Lipotoxicity, Oxidative stress, OA, oleate, 030220 oncology & carcinogenesis, Original Article, BSA, bovine serum albumin, GC–MS, gas chromatography–mass spectrometry, ER stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8abb056af369ca34e6c97f53de9251Test