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المؤلفون: Kit‐Kay Mak, Zhang Shiming, Ola Epemolu, Albena T. Dinkova‐Kostova, Geoffrey Wells, Irina G. Gazaryan, Raghavendra Sakirolla, Zulkefeli Mohd, Mallikarjuna Rao Pichika
المصدر: ChemistryOpen. 11
مصطلحات موضوعية: Lipopolysaccharides, Kelch-Like ECH-Associated Protein 1, NF-E2-Related Factor 2, Tumor Necrosis Factor-alpha, Interleukin-6, NF-kappa B, Anti-Inflammatory Agents, Thiophenes, General Chemistry, Dinoprostone, Rats, Mice, Cyclooxygenase 2, Humans, Animals, Cytokines, RNA, Messenger, Inflammation Mediators
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5858605998fcc3df15b9481074bfd558Test
https://doi.org/10.1002/open.202200181Test -
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المؤلفون: Kit-Kay Mak, Zhang Shiming, Jun Sheng Low, Madhu Katyayani Balijepalli, Raghavendra Sakirolla, Albena T. Dinkova-Kostova, Ola Epemolu, Zulkefeli Mohd, Mallikarjuna Rao Pichika
المصدر: Molecules; Volume 27; Issue 15; Pages: 4992
مصطلحات موضوعية: Flavonoids, Lipopolysaccharides, Glycogen Synthase Kinase 3 beta, Kelch-Like ECH-Associated Protein 1, NF-E2-Related Factor 2, Organic Chemistry, Anti-Inflammatory Agents, NF-kappa B, Pharmaceutical Science, Nitric Oxide, Amides, Rats, Analytical Chemistry, Molecular Docking Simulation, Mice, Chemistry (miscellaneous), Drug Discovery, Animals, Cytokines, Humans, Molecular Medicine, Physical and Theoretical Chemistry, Heme Oxygenase-1, auranamide, patriscabratine, Melastoma malabathricum, NRF2, KEAP1, anti-inflammatory
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8826c704a8ff88a56dc443453de3304cTest
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المؤلفون: Angus W. Jackson, Rita Moreno, Albena T. Dinkova-Kostova, Sourav Banerjee, Jean A. Quinn, Jack E. Dixon, Joanne Edwards, Gregg Baillie, Laureano de la Vega
المصدر: Cell Death and Differentiation
مصطلحات موضوعية: Cell biology, Biology, Protein Serine-Threonine Kinases, Transfection, Article, Prognostic markers, Breast cancer, Heat Shock Transcription Factors, medicine, Humans, Protein folding, HSF1, Molecular Biology, Transcription factor, Triple-negative breast cancer, Cancer, Kinase, fungi, Protein-Tyrosine Kinases, medicine.disease, Prognosis, Cancer cell, Cancer research, Phosphorylation, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce0d718f23811e300b07b9467c9f015Test
http://europepmc.org/articles/PMC8166837Test -
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المؤلفون: John D. Hayes, Albena T. Dinkova-Kostova, Kenneth D. Tew
المصدر: Cancer Cell
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Apoptosis, Pentose phosphate pathway, medicine.disease_cause, Article, Antioxidants, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, HSF1, Transcription factor, chemistry.chemical_classification, Reactive oxygen species, AMPK, Cell Biology, Cell biology, Oxidative Stress, Glucose, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer cell, Energy Metabolism, Reactive Oxygen Species, Carcinogenesis, NADP, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15eff6d207e38ee78ac1ab60ade16d2Test
https://doi.org/10.1016/j.ccell.2020.06.001Test -
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المؤلفون: Tatsuro Iso, Geoffrey Wells, Seizo Koshiba, Takafumi Suzuki, Takashi Kamei, Albena T. Dinkova-Kostova, Jin Inoue, Yuta Horie, Tsunehiro Mizushima, Terry W. Moore, Masayuki Yamamoto, Takuma Kasai
المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biologyمصطلحات موضوعية: 0301 basic medicine, Molecular biology, NF-E2-Related Factor 2, Protein Conformation, QH301-705.5, Hinge, Medicine (miscellaneous), digestive system, environment and public health, Article, General Biochemistry, Genetics and Molecular Biology, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Humans, Protein Interaction Domains and Motifs, Inducer, Biology (General), Binding Sites, Kelch-Like ECH-Associated Protein 1, Mechanism (biology), Chemistry, Nuclear magnetic resonance spectroscopy, respiratory system, Cytoprotection, KEAP1, Keap1 nrf2, 030104 developmental biology, 030220 oncology & carcinogenesis, Biophysics, Disease prevention, General Agricultural and Biological Sciences, Solution-state NMR, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b389db1174491fece623799eefbceTest
https://doi.org/10.1038/s42003-021-02100-6Test -
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المؤلفون: Steven O′Reilly, Albena T. Dinkova-Kostova, John Henderson, Sharadha Dayalan Naidu, Stefan Przyborski, Richard Stratton
المصدر: Cells, 2021, Vol.10(8) [Peer Reviewed Journal]
Cells; Volume 10; Issue 8; Pages: 2053
Cells
Cells, Vol 10, Iss 2053, p 2053 (2021)مصطلحات موضوعية: QH301-705.5, systemic sclerosis, NF-E2-Related Factor 2, medicine.medical_treatment, Down-Regulation, Article, Nrf2, Transforming Growth Factor beta1, Mice, Downregulation and upregulation, Fibrosis, medicine, NAD(P)H Dehydrogenase (Quinone), Animals, Humans, Biology (General), Interleukin 6, chemistry.chemical_classification, Mice, Knockout, Reactive oxygen species, Scleroderma, Systemic, biology, integumentary system, Interleukin-6, fibrosis, Connective Tissue Growth Factor, Succinates, General Medicine, Transforming growth factor beta, Fibroblasts, medicine.disease, C700, Connective tissue disease, Molecular biology, Antioxidant Response Elements, Up-Regulation, Heme oxygenase, MicroRNAs, Cytokine, chemistry, itaconate, biology.protein, metabolism, Collagen, Reactive Oxygen Species, Heme Oxygenase-1
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca68670e6790373ccb3a2ff9f8bbf0fTest
http://dro.dur.ac.uk/35213Test/ -
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المؤلفون: Tim De Meyer, Louis Coussement, Maureen Higgins, Elena V. Knatko, Albena T. Dinkova-Kostova, Sandra Steyaert, Charlotte M. Proby, Kevin Roth
المصدر: EBIOMEDICINE
EBioMedicine, Vol 67, Iss, Pp 103383-(2021)
EBioMedicineمصطلحات موضوعية: 5mC, 5-methylcytosine, 0301 basic medicine, Medicine (General), DOWN-REGULATION, Research paper, Skin Neoplasms, NHK, normal human keratinocyte, Bisulfite sequencing, iHS, independent healthy skin, Mice, chemistry.chemical_compound, 0302 clinical medicine, DS, dorsal skin, Medicine and Health Sciences, Filip1l, Filament A interacting protein 1-like, iso, isoform, 5hmC, 5-hydroxymethylcytosine, cSCC, cutaneous squamous cell carcinoma, DNA methylation, CARCINOGENESIS, DMR, differentially methylated region, General Medicine, Methylation, Gene Expression Regulation, Neoplastic, 5-Methylcytosine, CpG site, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, CGI, CpG island, Medicine, cSCC, INTERACTING PROTEIN 1-LIKE, EXPRESSION, NMSC, non-melanoma skin cancer, INHIBITION, Down-Regulation, CpG, 5′-Cytosinephosphate-Guanine-3′, Biology, FILIP1L, General Biochemistry, Genetics and Molecular Biology, UVR, Ultraviolet radiation, 03 medical and health sciences, Tet, Ten-eleven-translocase, R5-920, Cell Line, Tumor, BENEFITS, Animals, Humans, Gene, 5-Hydroxymethylcytosine, VS, ventral skin, RRBS, SKIN-CANCER, LANDSCAPE, MUTATIONS, Promoter, (ox)RRBS, (oxidative) reduced representation bisulfite sequencing, ssUV mcSCC, solar simulated mouse cSCC, AK, actinic keratosis, Cytoskeletal Proteins, 030104 developmental biology, chemistry, Cancer research, RADIATION, Carrier Proteins
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9a728692e7f11d9c3617585e44f154Test
https://hdl.handle.net/1854/LU-8741083Test -
8KEAP1, a cysteine-based sensor and a drug target for the prevention and treatment of chronic disease
المؤلفون: Sharadha Dayalan Naidu, Albena T. Dinkova-Kostova
المصدر: Open Biology
Open Biology, Vol 10, Iss 6 (2020)مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, antioxidant, NF-E2-Related Factor 2, Immunology, Inflammation, Review, Review Article, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, NRF2, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, medicine, Humans, Molecular Targeted Therapy, lcsh:QH301-705.5, cysteine, Transcription factor, anti-inflammatory, 030304 developmental biology, Clinical Trials as Topic, 0303 health sciences, Kelch-Like ECH-Associated Protein 1, biology, General Neuroscience, Ubiquitination, respiratory system, KEAP1, Cytoprotection, Cell biology, Ubiquitin ligase, lcsh:Biology (General), redox, 030220 oncology & carcinogenesis, Chronic Disease, biology.protein, medicine.symptom, Cullin, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7017809c3d739b04628aa127f1f19a38Test
https://doi.org/10.1098/rsob.200105Test -
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المصدر: Molecules, Vol 24, Iss 19, p 3593 (2019)
Moleculesمصطلحات موضوعية: 0301 basic medicine, Pharmaceutical Science, sulforaphane, Disease, Review, Bioinformatics, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Anti-Infective Agents, Isothiocyanates, Drug Discovery, Medicine, nrf2, Glucoraphanin, Clinical Trials as Topic, Molecular Structure, 3. Good health, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Sulfoxides, Chemoprotective, Molecular Medicine, allometric scaling, chemoprotection, Brassica, lcsh:QD241-441, 03 medical and health sciences, lcsh:Organic chemistry, Biomarkers, Tumor, Animals, Humans, Microbiome, Physical and Theoretical Chemistry, broccoli, clinical trials, business.industry, Plant Extracts, glucoraphanin, Organic Chemistry, myrosinase, toxicity, Antineoplastic Agents, Phytogenic, Bioavailability, Clinical trial, 030104 developmental biology, chemistry, Isothiocyanate, business, Sulforaphane
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b2496ac3653b236a87628394c1f7d0Test
https://www.mdpi.com/1420-3049/24/19/3593Test -
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المؤلفون: W. David Holtzclaw, Jay H. Kalin, Abdulkerim Eroglu, Albena T. Dinkova-Kostova, Hua Liu, Charlotte M. Proby, Irene M. Leigh, Jed W. Fahey, Philip A. Cole
المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0213095 (2019)مصطلحات موضوعية: Neoplasms, Radiation-Induced, Skin Neoplasms, Light, Carcinogenesis, Pyridines, Administration, Topical, Cell, Cancer Treatment, Gene Expression, medicine.disease_cause, Biochemistry, Histones, 030207 dermatology & venereal diseases, Mice, 0302 clinical medicine, Medicine and Health Sciences, Post-Translational Modification, Multidisciplinary, integumentary system, Chromosome Biology, Physics, Chromatin Modification, Histone deacetylase inhibitor, Chemical Reactions, Squamous Cell Carcinomas, Acetylation, Histone Modification, Animal Models, Chromatin, 3. Good health, Tumor Burden, Physical sciences, Gene Expression Regulation, Neoplastic, Chemistry, medicine.anatomical_structure, Oncology, Experimental Organism Systems, 030220 oncology & carcinogenesis, Benzamides, Carcinoma, Squamous Cell, Medicine, Epigenetics, Keratinocyte, Research Article, Ultraviolet radiation, Cyclin-Dependent Kinase Inhibitor p21, medicine.drug_class, Cell Survival, Science, Histone Acetylation, Mouse Models, Research and Analysis Methods, Carcinomas, 03 medical and health sciences, Model Organisms, Electromagnetic radiation, Cell Line, Tumor, DNA-binding proteins, Carcinoma, medicine, Genetics, Animals, Humans, Cell Proliferation, Mice, Hairless, Biology and life sciences, business.industry, Proteins, Cancers and Neoplasms, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, Hairless, Histone Deacetylase Inhibitors, Cancer research, Animal Studies, Histone deacetylase, business, Ultraviolet B
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5541a74e2e97503f7eb40aac73e20c52Test
http://europepmc.org/articles/PMC6415858Test