المؤلفون: Tatsuro Iso, Geoffrey Wells, Seizo Koshiba, Takafumi Suzuki, Takashi Kamei, Albena T. Dinkova-Kostova, Jin Inoue, Yuta Horie, Tsunehiro Mizushima, Terry W. Moore, Masayuki Yamamoto, Takuma Kasai

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology

مصطلحات موضوعية: 0301 basic medicine, Molecular biology, NF-E2-Related Factor 2, Protein Conformation, QH301-705.5, Hinge, Medicine (miscellaneous), digestive system, environment and public health, Article, General Biochemistry, Genetics and Molecular Biology, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Humans, Protein Interaction Domains and Motifs, Inducer, Biology (General), Binding Sites, Kelch-Like ECH-Associated Protein 1, Mechanism (biology), Chemistry, Nuclear magnetic resonance spectroscopy, respiratory system, Cytoprotection, KEAP1, Keap1 nrf2, 030104 developmental biology, 030220 oncology & carcinogenesis, Biophysics, Disease prevention, General Agricultural and Biological Sciences, Solution-state NMR, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b389db1174491fece623799eefbceTest
https://doi.org/10.1038/s42003-021-02100-6Test

المؤلفون: Dylan G. Ryan, Elena V. Knatko, Alva M. Casey, Jens L. Hukelmann, Sharadha Dayalan Naidu, Alejandro J. Brenes, Thanapon Ekkunagul, Christa Baker, Maureen Higgins, Laura Tronci, Efterpi Nikitopolou, Tadashi Honda, Richard C. Hartley, Luke A.J. O’Neill, Christian Frezza, Angus I. Lamond, Andrey Y. Abramov, J. Simon C. Arthur, Doreen A. Cantrell, Michael P. Murphy, Albena T. Dinkova-Kostova

المساهمون: Murphy, Mike [0000-0003-1115-9618], Apollo - University of Cambridge Repository

المصدر: iScience, Vol 25, Iss 2, Pp 103827-(2022)

مصطلحات موضوعية: Proteomics, Multidisciplinary, Science, FOS: Clinical medicine, Immunology, respiratory system, environment and public health, Biochemistry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2450485bcdc6221e5a6ee31371e2554Test
https://doi.org/10.1016/j.isci.2022.103827Test

المؤلفون: Holly Robertson, Albena T. Dinkova-Kostova, John D. Hayes

المصدر: Cancers
Cancers, Vol 12, Iss 3609, p 3609 (2020)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, antioxidant, recurrent disease, Review, adaptation, medicine.disease_cause, chemotherapy, environment and public health, head and neck, 0302 clinical medicine, Cullin 3, oncogene, oxidative stress, chemoprevention, rectum, ATF4, glutathione, bladder, reactive oxygen species, NADPH generation, respiratory system, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, 030220 oncology & carcinogenesis, stomach, autophagy, tumour suppressor, pentose phosphate pathway, Biology, liver, lcsh:RC254-282, digestive system, NRF2, lung, 03 medical and health sciences, Downregulation and upregulation, medicine, metastasis, Protein kinase B, PI3K/AKT/mTOR pathway, bioactivation, drug resistance, oesophagus, colon, Cancer, thioredoxin, medicine.disease, KEAP1, NFE2L2, drug metabolism, initiation, 030104 developmental biology, proteasome, quinone-containing drugs, Cancer research, progression, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14afe79e3e505f682180a1993dd1f57Test
https://pubmed.ncbi.nlm.nih.gov/33276631Test

المؤلفون: Eduardo Muñoz, Albena T. Dinkova-Kostova, María E. Prados, Giovanni Apendino, Laura Casares, Juan D. Unciti-Broceta, Maureen Higgins, Laureano de la Vega, Diego Caprioglio, Daiana Mattoteia

المصدر: Redox Biology
Redox Biology, Vol 37, Iss, Pp 101689-(2020)

مصطلحات موضوعية: Antioxidant, NF-E2-Related Factor 2, medicine.medical_treatment, Short Communication, Clinical Biochemistry, Inflammation, Pharmacology, medicine.disease_cause, Biochemistry, Neuroprotection, environment and public health, digestive system, Antioxidants, Cannabidiol derivative/ NRF2/ BACH1/ HMOX1/ neurodegenerative diseases, Cell Line, Mice, In vivo, medicine, Animals, lcsh:QH301-705.5, lcsh:R5-920, Chemistry, Multiple sclerosis, Organic Chemistry, Nrf2 activators, Neurodegenerative Diseases, respiratory system, medicine.disease, Disease Models, Animal, Oxidative Stress, Basic-Leucine Zipper Transcription Factors, lcsh:Biology (General), medicine.symptom, lcsh:Medicine (General), Cannabidiol, Oxidative stress, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de4a453fd64e589b62478d05efde73bTest
https://pubmed.ncbi.nlm.nih.gov/32863231Test

المؤلفون: Albena T. Dinkova-Kostova, Jean A. Quinn, Joanne Edwards, Laura Casares, Gunjit Maan, Laura Torrente, Angus W. Jackson, Silvio Bicciato, Ying Zhang, Jani Saarela, Laureano de la Vega, Evgeny Kulesskiy, Asma Oumkaltoum Rezig, Andrea Grilli

المساهمون: Institute for Molecular Medicine Finland, University of Helsinki, Biosciences

المصدر: Biomolecules, Vol 10, Iss 1365, p 1365 (2020)
Biomolecules

مصطلحات موضوعية: 0301 basic medicine, POTENT AURORA KINASE, Colorectal cancer, Drug Evaluation, Preclinical, lcsh:QR1-502, environment and public health, Biochemistry, lcsh:Microbiology, NEGATIVE REGULATION, PATHWAY, 0302 clinical medicine, Urea, Medicine, Drug screening, NRF2, SMALL-MOLECULE INHIBITOR, Hyperactivation, Kinase, Communication, TUMOR-GROWTH, respiratory system, 3. Good health, Gene Expression Regulation, Neoplastic, PHASE-I, 030220 oncology & carcinogenesis, Colorectal Neoplasms, Signal Transduction, EXPRESSION, Cell Survival, NF-E2-Related Factor 2, In silico, Aurora inhibitor, colorectal cancer, digestive system, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, Humans, LUNG-CARCINOMA, drug screening, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, business.industry, medicine.disease, KEAP1, 030104 developmental biology, Drug Resistance, Neoplasm, Cell culture, Cancer cell, Cancer research, 1182 Biochemistry, cell and molecular biology, Benzimidazoles, 3111 Biomedicine, business, RESISTANCE

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db5a8ccdf6881c79812ba3a75b4bdf6Test
https://doi.org/10.3390/biom10101365Test

المؤلفون: Albena T. Dinkova-Kostova, John D. Hayes

المصدر: Molecular cell. 68(1)

مصطلحات موضوعية: 0301 basic medicine, Epigenomics, NF-E2-Related Factor 2, Cell, Regulator, Biology, environment and public health, Antioxidants, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, medicine, Humans, Epigenetics, Molecular Biology, Mechanism (biology), Cell Biology, respiratory system, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Acetylation, Cancer cell, Suppressor, Oxidation-Reduction, Protein Processing, Post-Translational, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6872d90ba1b81ed213056a29ab8ce5a8Test
https://pubmed.ncbi.nlm.nih.gov/28985511Test

المؤلفون: James Ferguson, Paul Talalay, Ying Zhang, Jed W. Fahey, Albena T. Dinkova-Kostova, Sukirti Kalra, Akira Saito, Suqing Zheng, Maureen Higgins, Elena V. Knatko, Charlotte M. Proby, Robert S. Dawe, Sally H. Ibbotson, Jeffrey T.-J. Huang, Rosemary G. Clarke, Andrea L. Benedict, Tadashi Honda

المصدر: Cancer Prevention Research. 8:475-486

مصطلحات موضوعية: Cancer Research, Skin erythema, Neoplasms, Radiation-Induced, Skin Neoplasms, NF-E2-Related Factor 2, Ultraviolet Rays, Blotting, Western, Biology, Real-Time Polymerase Chain Reaction, medicine.disease_cause, environment and public health, Article, Mice, Downregulation and upregulation, Solar Energy, medicine, Animals, Humans, RNA, Messenger, Carcinogen, Skin, Mice, Knockout, Mice, Hairless, Reverse Transcriptase Polymerase Chain Reaction, Activator (genetics), Interleukin, respiratory system, Healthy Volunteers, Hairless, Mice, Inbred C57BL, Oxidative Stress, Oncology, Immunology, Cancer research, Female, Carcinogenesis, Biomarkers, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d612ec6c81346da85ab140b7f521e02Test
https://doi.org/10.1158/1940-6207.capr-14-0362Test

المؤلفون: Colúm Connolly, Clemens Steegborn, Donald C. Lo, Albena T. Dinkova-Kostova, Andrew Snyder, Vanita Chopra, Alexei Degterev, Michael A. Schwarzschild, Cho Low, Ulrike Träger, Leslie M. Thompson, Michael J. Van Kanegan, James R. Miller, Matthew Fuszard, Ningzhe Zhang, Ellen Sapp, Susanta Samajdar, Lisa Meisel, Kimberly B. Kegel-Gleason, Petr Vodicka, Adelaide Tousley, Lisa M. Ellerby, David Llères, Sébastien Moniot, Aleksey G. Kazantsev, Steven M. Hersch, Lisa A. Crawford, Ross S. Stein, Sarah J. Tabrizi, Eranthie Weerapana, Vijay Potluri, Linda S. Kaltenbach, Ruth Farmer, Blair R. Leavitt, Maureen Higgins, Luisa Quinti, Marian DiFiglia, Sharadha Dayalan Naidu, Xiqun Chen

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 23

مصطلحات موضوعية: 0301 basic medicine, Huntington's Disease, Male, Protein Conformation, Neurodegenerative, Inbred C57BL, environment and public health, Mice, Neural Stem Cells, NRF2 inducer, 2.1 Biological and endogenous factors, Aetiology, Cells, Cultured, Multidisciplinary, Cultured, Kelch-Like ECH-Associated Protein 1, biology, Microglia, Signal transducing adaptor protein, Brain, Middle Aged, respiratory system, Neural stem cell, Ubiquitin ligase, Cell biology, medicine.anatomical_structure, Huntington Disease, Neuroprotective Agents, Biochemistry, PNAS Plus, Cytokines, Female, Signal transduction, KEAP1/NRF2/ARE signaling, Huntington’s disease, Signal Transduction, Adult, antiinflammatory responses, NF-E2-Related Factor 2, Cells, 1.1 Normal biological development and functioning, digestive system, Proinflammatory cytokine, 03 medical and health sciences, Rare Diseases, Huntington's disease, Clinical Research, Underpinning research, medicine, Genetics, Animals, Humans, Transcription factor, Aged, Animal, Macrophages, Neurosciences, MPTP Poisoning, medicine.disease, Stem Cell Research, Brain Disorders, Rats, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, human neural stem cells, HEK293 Cells, Disease Models, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bba6be10075b3b40875d35cd1e72bd7Test
https://researchonline.lshtm.ac.uk/id/eprint/3931063/1/KEAP1.pdfTest

المؤلفون: Lee Stanyer, Annapurna Chalasani, Andrey Y. Abramov, Kira M. Holmström, Ying Zhang, Iain P. Hargreaves, Masayuki Yamamoto, Liam Baird, John M. Land, Albena T. Dinkova-Kostova

المصدر: Biology Open, Vol 2, Iss 8, Pp 761-770 (2013)
Biology Open

مصطلحات موضوعية: RM, Keap1, Bioenergetics, QH301-705.5, Science, Oxidative phosphorylation, Mitochondrion, Biology, digestive system, environment and public health, General Biochemistry, Genetics and Molecular Biology, Nrf2, 03 medical and health sciences, QH301, 0302 clinical medicine, Respiration, Glycolysis, Biology (General), QH426, 030304 developmental biology, Membrane potential, 0303 health sciences, Energy metabolism, respiratory system, Cytoprotection, Cell biology, Mitochondria, Biochemistry, ATP–ADP translocase, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec1b248cd7a0095495651221e1d2e95Test
http://bio.biologists.org/content/2/8/761Test

المؤلفون: Paul J, Meakin, Sudhir, Chowdhry, Ritu S, Sharma, Fiona B, Ashford, Shaun V, Walsh, Rory J, McCrimmon, Albena T, Dinkova-Kostova, John F, Dillon, John D, Hayes, Michael L J, Ashford

المصدر: Molecular and Cellular Biology

مصطلحات موضوعية: Male, Mice, Knockout, NF-E2-Related Factor 2, Lipogenesis, Articles, respiratory system, AMP-Activated Protein Kinases, Diet, High-Fat, Endoplasmic Reticulum Stress, Lipid Metabolism, Liver Cirrhosis, Experimental, environment and public health, digestive system, Mice, Inbred C57BL, Mice, Oxidative Stress, Liver, Non-alcoholic Fatty Liver Disease, Unfolded Protein Response, Animals, Disease Susceptibility, Insulin Resistance, Phosphorylation, Acetyl-CoA Carboxylase, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::d64756dc65c9535439ca62653e238545Test
https://pubmed.ncbi.nlm.nih.gov/24958099Test