Zopfiellasins A–D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment
| العنوان: | Zopfiellasins A–D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment |
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| المؤلفون: | Ji-Kai Liu, Zheng-Hui Li, Juan He, Tao Feng, Jie-Yu Zhang |
| المصدر: | Molecules Volume 26 Issue 18 Molecules, Vol 26, Iss 5611, p 5611 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Magnetic Resonance Spectroscopy, Stereochemistry, Actinidia, Sordariales, Pharmaceutical Science, Zopfiella, Organic chemistry, Pseudomonas syringae, Fungus, Zopfiella sp, Article, Analytical Chemistry, Pseudomonas syringae pv. actinidiae, chemistry.chemical_compound, QD241-441, cytochalasins, X-Ray Diffraction, Drug Discovery, Cytochalasin, Physical and Theoretical Chemistry, biology, Stereoisomerism, biology.organism_classification, Anti-Bacterial Agents, antibacterial, chemistry, Chemistry (miscellaneous), Kiwi, Mic values, Molecular Medicine, Antibacterial activity |
| الوصف: | In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp. The structures were established on the basis of spectroscopic data analysis, while the absolute configurations were determined by single-crystal X-ray diffraction. Compounds 1 and 3 exhibited antibacterial activity against Psa with MIC values of 25 and 50 μg/mL, respectively. This is the first report of anti-Psa activity of cytochalasin derivatives. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1420-3049 |
| DOI: | 10.3390/molecules26185611 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e2c78ce26f8288ab91e9e920e777bbTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a7e2c78ce26f8288ab91e9e920e777bb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14203049 |
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| DOI: | 10.3390/molecules26185611 |