دورية أكاديمية
Human T-lymphotropic virus type 1 infection is frequent in rural communities of the southern Andes of Peru
| العنوان: | Human T-lymphotropic virus type 1 infection is frequent in rural communities of the southern Andes of Peru |
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| المؤلفون: | Ita, Fanny, Mayer, Erick F., Verdonck, Kristien, Gonzalez, Elsa, Clark, Daniel, Gotuzzo, Eduardo |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2013 |
| المجموعة: | Repositorio - UPCH (Universidad Peruana Cayetano Heredia) |
| مصطلحات موضوعية: | Peru, Adult, Female, Humans, Male, Cohort Studies, Cross-Sectional Studies, Aged, 80 and over, Middle Aged, Peru/epidemiology, Rural Population, Prevalence, Risk Factors, Andes, Breast Feeding, Breastfeeding, HTLV-I Infections/epidemiology/virology, Human T-lymphotropic virus 1/immunology, Human T-lymphotropic virus type 1, https://purl.org/pe-repo/ocde/ford#3.02.00Test, https://purl.org/pe-repo/ocde/ford#3.03.08Test |
| الوصف: | OBJECTIVES: To evaluate the presence of human T-lymphotropic virus type 1 (HTLV-1) infection in isolated rural communities in the southern Andes of Peru. METHODS: We conducted a cross-sectional study in five communities located in three provinces in Ayacucho, Peru. The five communities are located at >3000 meters above sea level and are mainly rural, and more than 85% of the population speaks Quechua. Volunteers aged 12 years and older were included. Clinical and epidemiological data were collected, along with a blood sample for serological testing. RESULTS: We included 397 participants; their median age was 41 years (interquartile range 31-57 years) and 69% were women. According to our definitions, 98% were of Quechua origin. HTLV-1 was diagnosed in 11 people: 0/164 in Cangallo, 3/154 (2%) in Vilcashuaman, and 8/79 (10%) in Parinacochas. There were no cases of HTLV-2. All the HTLV-1-positive participants were born in Ayacucho and were of Quechua origin; they ranged in age from 29 to 87 years (median 56 years) and 10/11 were women. Ten were apparently healthy, and one woman was diagnosed with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Three out of 11 had a family member with a lower limb impairment compatible with HAM/TSP. CONCLUSION: The fact that HTLV-1 infection was present in two out of three provinces suggests that HTLV-1 could be highly endemic in the southern Andes in the Quechua population. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1878-3511 |
| العلاقة: | urn:issn:1878-3511; https://hdl.handle.net/20.500.12866/8029Test; https://doi.org/10.1016/j.ijid.2013.10.005Test |
| DOI: | 10.1016/j.ijid.2013.10.005 |
| الإتاحة: | https://doi.org/20.500.12866/8029Test https://doi.org/10.1016/j.ijid.2013.10.005Test https://hdl.handle.net/20.500.12866/8029Test |
| حقوق: | info:eu-repo/semantics/restrictedAccess ; https://creativecommons.org/licenses/by-nc-nd/4.0/deed.esTest |
| رقم الانضمام: | edsbas.C7C79FC9 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 18783511 |
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| DOI: | 10.1016/j.ijid.2013.10.005 |