نتائج البحث - "Histone Acetyltransferases"

1

دورية أكاديمية

Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.

المؤلفون: Domingues, Ana Filipa, Kulkarni, Rashmi, Giotopoulos, George, Gupta, Shikha, Vinnenberg, Laura, Arede, Liliana, Foerner, Elena, Khalili, Mitra, Adao, Rita Romano, Johns, Ayona, Tan, Shengjiang, Zeka, Keti, Huntly, Brian J, Prabakaran, Sudhakaran, Pina, Cristina

مصطلحات موضوعية: Kat2a, Single-cell RNA seq, acute myeloid leukaemia, cancer biology, chromosomes, epigenetics, gene expression, mouse, transcriptional bursting, transcriptional heterogeneity, Animals, Chromatin, Histone Acetyltransferases, Humans, Leukemia, Myeloid, Acute, Mice, Knockout, Neoplastic Stem Cells, Single-Cell Analysis, Transcription, Genetic, Transcriptome

وصف الملف: Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/303706Test

الإتاحة: https://doi.org/10.17863/CAM.50784Test
https://www.repository.cam.ac.uk/handle/1810/303706Test

View record in BASE

2

The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy

المؤلفون: Peiqing Liu, Zhuoming Li, Junjian Wang, Sidong Cai, Rui Lan, Zhirong Lin, Zhen Guo, Jingyan Li, Zhenzhen Li

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1286-1299 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Hypertrophic genes, ISO, isoproterenol, PARP1, poly(ADP-ribose)polymerase-1, TSS, transcription start sites, RNA polymerase II, LVAW, left ventricular anterior wall thickness, LVPW, left ventricular posterior wall thickness, PARP1, TL, tibia length, NS, normal saline, NC, negative control, BET, bromodomain and extraterminal domain, 0302 clinical medicine, HATs, histone acetyltransferases, Gene expression, Transcription activation, co-IP, co-immunoprecipitation, General Pharmacology, Toxicology and Pharmaceutics, HW, heart weight, 0303 health sciences, siRNA, small-interfering RNA, PSR, picrosirius red, biology, FS, fractional shortening, Chemistry, BW, body weight, Chromatin, Cell biology, Cardiac hypertrophy, 030220 oncology & carcinogenesis, PBS, phosphate buffer solution, Phosphorylation, BRD4, Original Article, WGA, wheat germ agglutinin, RM1-950, 03 medical and health sciences, FBS, fetal bovine serum, HE, hematoxylin-eosin, RNA Pol II, RNA polymerases II, RNA Pol II, Gene silencing, EF, ejection fraction, IF, immunofluorescence, ANP, atrial natriuretic peptide, CDK9, cyclin-dependent kinase 9, 030304 developmental biology, LVID, left ventricular internal diameter, BNP, brain natriuretic polypeptide, NRCMs, neonatal rat cardiomyocytes, β-AR, β-adrenergic receptor, Isoproterenol, HDACs, histone deacetylases, Bromodomain, PARylation, biology.protein, SD, Sprague–Dawley, β-MHC, β-myosin heavy chain, Therapeutics. Pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fde96e7c9d22c0d4144a0bf59c2cb8Test
http://www.sciencedirect.com/science/article/pii/S2211383520308455Test

3

Histone acetylation and the role of histone deacetylases in normal cyclic endometrium

المؤلفون: Palak Gujral, Vishakha Mahajan, Anna P. Ponnampalam, Abbey C. Lissaman

المصدر: Reproductive Biology and Endocrinology, Vol 18, Iss 1, Pp 1-11 (2020)
Reproductive Biology and Endocrinology : RB&E

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH471-489, Endometriosis, Review, Endometrium, lcsh:Gynecology and obstetrics, Histone Deacetylases, Epigenesis, Genetic, Histones, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Gene expression, medicine, Humans, lcsh:Reproduction, Epigenetics, lcsh:RG1-991, Histone Acetyltransferases, Histone deacetylation, 030219 obstetrics & reproductive medicine, biology, Endometrial cancer, Regeneration (biology), Obstetrics and Gynecology, Acetylation, medicine.disease, Cell biology, Chromatin, Endometrial Neoplasms, 030104 developmental biology, Histone, medicine.anatomical_structure, Reproductive Medicine, Histone acetylation, biology.protein, Female, Protein Processing, Post-Translational, Menstrual cycle, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a729b6483b6d27d379e5566e39df11c0Test
http://link.springer.com/article/10.1186/s12958-020-00637-5Test

4

A short guide to histone deacetylases including recent progress on class II enzymes

المؤلفون: Jeong-Sun Kim, Suk-Youl Park

المصدر: Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 204-212 (2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be1344bbceab5fc409e38ac6dcb02e0Test
http://europepmc.org/articles/PMC7062823Test

5

Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter

المؤلفون: Liane Dupont, Megan McIntosh, Madeleine Poulter, Lily Du, Matthew B. Reeves, Stephanie Choi

المساهمون: Dupont, Liane [0000-0002-2124-4069], Apollo - University of Cambridge Repository

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Cytomegalovirus, Biochemistry, epigenetic regulation, chromatin modification, 03 medical and health sciences, herpesvirus, cell signaling, Humans, Histone acetyltransferase activity, Gene Regulation, lysine acetyltransferase 6A (KAT6A), Src family kinase, Promoter Regions, Genetic, Protein kinase A, Molecular Biology, Cells, Cultured, Histone Acetyltransferases, 030102 biochemistry & molecular biology, biology, Chemistry, histone acetylation, phosphoproteomics, Zinc Fingers, Cell Biology, Histone acetyltransferase, 3. Good health, Cell biology, Chromatin, hematopoietic cell kinase, src-Family Kinases, 030104 developmental biology, Histone phosphorylation, Histone, cytomegalovirus reactivation, gene expression, biology.protein, Virus Activation

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71275f7a5ac69b3ccbbf34c8db479f6fTest
https://doi.org/10.1074/jbc.ra119.009667Test

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Reduction in gene expression noise by targeted increase in accessibility at gene loci

المؤلفون: Supravat Dey, Ryan J. Dikdan, La Tasha C.R. Fraser, Sanjay Tyagi, Abhyudai Singh

المصدر: Proc Natl Acad Sci U S A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c551b092565a15a04644df08781d73bfTest
https://doi.org/10.1073/pnas.2018640118Test

7

Quantitative control of noise in mammalian gene expression by dynamic histone regulation

المؤلفون: Xibin Lu, Wei Xu, Fan Jiang, Weimin Fan, Rui Chen, Yuejian Mo, Huiyu He, Yili Wang, Xi Chen, Wei Huang, Jiao Ma, Shu Gu, Deng Tan

المصدر: eLife
eLife, Vol 10 (2021)

مصطلحات موضوعية: Embryonal Carcinoma Stem Cells, Mouse, QH301-705.5, Science, General Biochemistry, Genetics and Molecular Biology, Histones, Mice, Transcription (biology), epigenetic bistability, Gene expression, Animals, Humans, histone modification, Epigenetics, Biology (General), Gene, Histone Acetyltransferases, General Immunology and Microbiology, biology, Chemistry, General Neuroscience, transcriptional activator, General Medicine, synthetic circuit, oscillation, Chromosomes and Gene Expression, HDAC4, Chromatin, Cell biology, Gene Expression Regulation, Neoplastic, Histone, gene expression noise, biology.protein, Medicine, Research Article, Computational and Systems Biology, Human, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621e7cfeffcc950a5cecb39c97e25a23Test
http://europepmc.org/articles/PMC8357418Test

8

SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis

المؤلفون: Daeyoup Lee, Minhoo Kim, Yoonjung Choi, Harim Kim

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Saccharomyces cerevisiae Proteins, Science, General Physics and Astronomy, Chromatin remodelling, 02 engineering and technology, Saccharomyces cerevisiae, Biology, Exosome, General Biochemistry, Genetics and Molecular Biology, RNA Transport, Article, 03 medical and health sciences, Stress, Physiological, Gene Expression Regulation, Fungal, Gene expression, RNA, Messenger, lcsh:Science, Histone Acetyltransferases, Messenger RNA, Multidisciplinary, Exosome Multienzyme Ribonuclease Complex, Proteasome, RNA, Nuclear Proteins, RNA-Binding Proteins, General Chemistry, 021001 nanoscience & nanotechnology, Adaptation, Physiological, Chromatin, Cell biology, Gene regulation, Messenger RNP, 030104 developmental biology, Proteostasis, Ribonucleoproteins, Trans-Activators, lcsh:Q, 0210 nano-technology, Biogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0561edf463df052c976808a64d55ccaeTest
http://link.springer.com/article/10.1038/s41467-019-10350-6Test

9

A global chromatin compaction pathway that represses germline gene expression during starvation

المؤلفون: Emilie Chien, Mezmur D. Belew, Matthew M. Wong, W. Matthew Michael

المصدر: The Journal of cell biology. 220(9)

مصطلحات موضوعية: Male, Embryo, Nonmammalian, Transcription, Genetic, Chromosomal Proteins, Non-Histone, Biology, Germline, Histones, 03 medical and health sciences, 0302 clinical medicine, AMP-Activated Protein Kinase Kinases, Transcription (biology), RNA interference, Gene expression, Animals, Heterochromatin assembly, RNA, Small Interfering, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Gene, 030304 developmental biology, Histone Acetyltransferases, Ovum, 0303 health sciences, Genome, Helminth, Kinase, Gene Expression Regulation, Developmental, Cell Biology, Chromatin Assembly and Disassembly, Spermatozoa, Chromatin, Cell biology, DNA Topoisomerases, Type II, Starvation, Larva, Protein Kinases, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d4ae7a44ca9956fb5f5abb3bab1397Test
https://pubmed.ncbi.nlm.nih.gov/34383014Test

10

JNK signaling-dependent regulation of histone acetylation are involved in anacardic acid alleviates cardiomyocyte hypertrophy induced by phenylephrine

المؤلفون: Bohui Peng, Chang Peng, Xiaomei Luo, Shuqi Wu, Qian Mao, Huanting Zhang, Xiao Han

المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261388 (2021)

مصطلحات موضوعية: Male, Cell signaling, Immunofluorescence, Gene Expression, Signal transduction, Biochemistry, Histones, Mice, Phenylephrine, Animal Cells, Medicine and Health Sciences, Myocytes, Cardiac, p300-CBP Transcription Factors, Post-Translational Modification, Histone Acetyltransferases, Cardiomyocytes, Anthracenes, Multidisciplinary, Chromosome Biology, Chromatin Modification, Chemical Reactions, Signaling cascades, Software Engineering, Acetylation, Histone Modification, Chromatin, c-Jun N-terminal kinase signaling cascade, Chemistry, Physical Sciences, Medicine, Engineering and Technology, Epigenetics, Female, Cellular Types, Anatomy, Mitogen-Activated Protein Kinases, Research Article, Computer and Information Sciences, China, MAPK signaling cascades, MAP Kinase Signaling System, Science, Histone Acetylation, Cardiac Hypertrophy, Primary Cell Culture, Muscle Tissue, Cardiology, Cardiomegaly, Research and Analysis Methods, Computer Software, DNA-binding proteins, Genetics, Animals, Immunoassays, Muscle Cells, Biology and Life Sciences, Proteins, Cell Biology, Anacardic Acids, Disease Models, Animal, Biological Tissue, Immunologic Techniques

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b098ef79c7f06b0f069071c626cd79Test
https://doi.org/10.1371/journal.pone.0261388Test

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