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المؤلفون: John D. Hayes, Albena T. Dinkova-Kostova, Kenneth D. Tew
المصدر: Cancer Cell
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Apoptosis, Pentose phosphate pathway, medicine.disease_cause, Article, Antioxidants, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, HSF1, Transcription factor, chemistry.chemical_classification, Reactive oxygen species, AMPK, Cell Biology, Cell biology, Oxidative Stress, Glucose, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer cell, Energy Metabolism, Reactive Oxygen Species, Carcinogenesis, NADP, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15eff6d207e38ee78ac1ab60ade16d2Test
https://doi.org/10.1016/j.ccell.2020.06.001Test -
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المؤلفون: Tatsuro Iso, Geoffrey Wells, Seizo Koshiba, Takafumi Suzuki, Takashi Kamei, Albena T. Dinkova-Kostova, Jin Inoue, Yuta Horie, Tsunehiro Mizushima, Terry W. Moore, Masayuki Yamamoto, Takuma Kasai
المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biologyمصطلحات موضوعية: 0301 basic medicine, Molecular biology, NF-E2-Related Factor 2, Protein Conformation, QH301-705.5, Hinge, Medicine (miscellaneous), digestive system, environment and public health, Article, General Biochemistry, Genetics and Molecular Biology, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Humans, Protein Interaction Domains and Motifs, Inducer, Biology (General), Binding Sites, Kelch-Like ECH-Associated Protein 1, Mechanism (biology), Chemistry, Nuclear magnetic resonance spectroscopy, respiratory system, Cytoprotection, KEAP1, Keap1 nrf2, 030104 developmental biology, 030220 oncology & carcinogenesis, Biophysics, Disease prevention, General Agricultural and Biological Sciences, Solution-state NMR, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b389db1174491fece623799eefbceTest
https://doi.org/10.1038/s42003-021-02100-6Test -
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المؤلفون: Zulkefeli Mohd, Albena T. Dinkova-Kostova, Madhu Katyayani Balijepalli, Mallikarjuna Rao Pichika, Kit-Kay Mak, Zhang Shiming, Ola Epemolu
المصدر: Phytomedicine Plus, Vol 1, Iss 1, Pp 100018-(2021)
مصطلحات موضوعية: Swietenine, Chemistry, medicine.drug_class, Mechanism (biology), General Engineering, Inflammation, Pharmacology, Anti-inflammatory, In vitro, NRF2, Other systems of medicine, Swietenia macrophylla, medicine, Microsome, General Earth and Planetary Sciences, NQO1, Metabolic stability, medicine.symptom, Tetranortriterpenoid, RZ201-999, General Environmental Science
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fcb039eae28402ac69effc2f33675cTest
http://www.sciencedirect.com/science/article/pii/S266703132030018XTest -
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المؤلفون: Christophe F. Hano, Albena T. Dinkova-Kostova, Laurence B. Davin, John R. Cort, Norman G. Lewis
المساهمون: Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), Université d'Orléans (UO)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), COSM'ACTIFS - Bioactifs et Cosmétiques, Université d'Orléans (UO)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ninewells Hospital and Medical School [Dundee], Johns Hopkins University School of Medicine [Baltimore], Washington State University (WSU), Pacific Northwest National Laboratory (PNNL)
المصدر: Frontiers in Plant Science
Frontiers in Plant Science, Frontiers, 2021, 11, ⟨10.3389/fpls.2020.630327⟩
Frontiers in Plant Science, Vol 11 (2021)مصطلحات موضوعية: 0303 health sciences, 010405 organic chemistry, Chemistry, [SDV]Life Sciences [q-bio], lignans metabolism, lignans, biological activity, analytical method, Computational biology, Plant Science, lcsh:Plant culture, Health benefits, 01 natural sciences, 0104 chemical sciences, Metabolic engineering, 03 medical and health sciences, chemistry.chemical_compound, Editorial, Biosynthesis, lcsh:SB1-1110, metabolic engineering, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ddf1e729b8dc012289c22e9c18cc10Test
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المؤلفون: Steven O′Reilly, Albena T. Dinkova-Kostova, John Henderson, Sharadha Dayalan Naidu, Stefan Przyborski, Richard Stratton
المصدر: Cells, 2021, Vol.10(8) [Peer Reviewed Journal]
Cells; Volume 10; Issue 8; Pages: 2053
Cells
Cells, Vol 10, Iss 2053, p 2053 (2021)مصطلحات موضوعية: QH301-705.5, systemic sclerosis, NF-E2-Related Factor 2, medicine.medical_treatment, Down-Regulation, Article, Nrf2, Transforming Growth Factor beta1, Mice, Downregulation and upregulation, Fibrosis, medicine, NAD(P)H Dehydrogenase (Quinone), Animals, Humans, Biology (General), Interleukin 6, chemistry.chemical_classification, Mice, Knockout, Reactive oxygen species, Scleroderma, Systemic, biology, integumentary system, Interleukin-6, fibrosis, Connective Tissue Growth Factor, Succinates, General Medicine, Transforming growth factor beta, Fibroblasts, medicine.disease, C700, Connective tissue disease, Molecular biology, Antioxidant Response Elements, Up-Regulation, Heme oxygenase, MicroRNAs, Cytokine, chemistry, itaconate, biology.protein, metabolism, Collagen, Reactive Oxygen Species, Heme Oxygenase-1
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca68670e6790373ccb3a2ff9f8bbf0fTest
http://dro.dur.ac.uk/35213Test/ -
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المؤلفون: Tim De Meyer, Louis Coussement, Maureen Higgins, Elena V. Knatko, Albena T. Dinkova-Kostova, Sandra Steyaert, Charlotte M. Proby, Kevin Roth
المصدر: EBIOMEDICINE
EBioMedicine, Vol 67, Iss, Pp 103383-(2021)
EBioMedicineمصطلحات موضوعية: 5mC, 5-methylcytosine, 0301 basic medicine, Medicine (General), DOWN-REGULATION, Research paper, Skin Neoplasms, NHK, normal human keratinocyte, Bisulfite sequencing, iHS, independent healthy skin, Mice, chemistry.chemical_compound, 0302 clinical medicine, DS, dorsal skin, Medicine and Health Sciences, Filip1l, Filament A interacting protein 1-like, iso, isoform, 5hmC, 5-hydroxymethylcytosine, cSCC, cutaneous squamous cell carcinoma, DNA methylation, CARCINOGENESIS, DMR, differentially methylated region, General Medicine, Methylation, Gene Expression Regulation, Neoplastic, 5-Methylcytosine, CpG site, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, CGI, CpG island, Medicine, cSCC, INTERACTING PROTEIN 1-LIKE, EXPRESSION, NMSC, non-melanoma skin cancer, INHIBITION, Down-Regulation, CpG, 5′-Cytosinephosphate-Guanine-3′, Biology, FILIP1L, General Biochemistry, Genetics and Molecular Biology, UVR, Ultraviolet radiation, 03 medical and health sciences, Tet, Ten-eleven-translocase, R5-920, Cell Line, Tumor, BENEFITS, Animals, Humans, Gene, 5-Hydroxymethylcytosine, VS, ventral skin, RRBS, SKIN-CANCER, LANDSCAPE, MUTATIONS, Promoter, (ox)RRBS, (oxidative) reduced representation bisulfite sequencing, ssUV mcSCC, solar simulated mouse cSCC, AK, actinic keratosis, Cytoskeletal Proteins, 030104 developmental biology, chemistry, Cancer research, RADIATION, Carrier Proteins
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9a728692e7f11d9c3617585e44f154Test
https://hdl.handle.net/1854/LU-8741083Test -
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المؤلفون: Eduardo Muñoz, Albena T. Dinkova-Kostova, María E. Prados, Giovanni Apendino, Laura Casares, Juan D. Unciti-Broceta, Maureen Higgins, Laureano de la Vega, Diego Caprioglio, Daiana Mattoteia
المصدر: Redox Biology
Redox Biology, Vol 37, Iss, Pp 101689-(2020)مصطلحات موضوعية: Antioxidant, NF-E2-Related Factor 2, medicine.medical_treatment, Short Communication, Clinical Biochemistry, Inflammation, Pharmacology, medicine.disease_cause, Biochemistry, Neuroprotection, environment and public health, digestive system, Antioxidants, Cannabidiol derivative/ NRF2/ BACH1/ HMOX1/ neurodegenerative diseases, Cell Line, Mice, In vivo, medicine, Animals, lcsh:QH301-705.5, lcsh:R5-920, Chemistry, Multiple sclerosis, Organic Chemistry, Nrf2 activators, Neurodegenerative Diseases, respiratory system, medicine.disease, Disease Models, Animal, Oxidative Stress, Basic-Leucine Zipper Transcription Factors, lcsh:Biology (General), medicine.symptom, lcsh:Medicine (General), Cannabidiol, Oxidative stress, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de4a453fd64e589b62478d05efde73bTest
https://pubmed.ncbi.nlm.nih.gov/32863231Test -
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المصدر: Molecules, Vol 24, Iss 19, p 3593 (2019)
Moleculesمصطلحات موضوعية: 0301 basic medicine, Pharmaceutical Science, sulforaphane, Disease, Review, Bioinformatics, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Anti-Infective Agents, Isothiocyanates, Drug Discovery, Medicine, nrf2, Glucoraphanin, Clinical Trials as Topic, Molecular Structure, 3. Good health, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Sulfoxides, Chemoprotective, Molecular Medicine, allometric scaling, chemoprotection, Brassica, lcsh:QD241-441, 03 medical and health sciences, lcsh:Organic chemistry, Biomarkers, Tumor, Animals, Humans, Microbiome, Physical and Theoretical Chemistry, broccoli, clinical trials, business.industry, Plant Extracts, glucoraphanin, Organic Chemistry, myrosinase, toxicity, Antineoplastic Agents, Phytogenic, Bioavailability, Clinical trial, 030104 developmental biology, chemistry, Isothiocyanate, business, Sulforaphane
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b2496ac3653b236a87628394c1f7d0Test
https://www.mdpi.com/1420-3049/24/19/3593Test -
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المؤلفون: Stjepana Kovac, Sharadha Dayalan Naidu, Andrey Y. Abramov, Ramona Eckel, Tawfeeq Shekh-Ahmad, Maureen Higgins, Masayuki Yamamoto, Matthew C. Walker, Albena T. Dinkova-Kostova
المصدر: Brain. 141:1390-1403
مصطلحات موضوعية: Male, 0301 basic medicine, Mice, Transgenic, Status epilepticus, Mitochondrion, Pharmacology, medicine.disease_cause, Epileptogenesis, Neuroprotection, Rats, Sprague-Dawley, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Excitatory Amino Acid Agonists, medicine, Animals, Cells, Cultured, Cerebral Cortex, Membrane Potential, Mitochondrial, Neurons, chemistry.chemical_classification, Hippocampal sclerosis, Reactive oxygen species, Kainic Acid, Kelch-Like ECH-Associated Protein 1, medicine.disease, Glutathione, Triterpenes, Rats, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Animals, Newborn, Gene Expression Regulation, chemistry, Mutation, Anticonvulsants, Neurology (clinical), medicine.symptom, Neuroglia, 030217 neurology & neurosurgery, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1761aa3e6338da370b0cc3a5957f4cTest
https://doi.org/10.1093/brain/awy071Test -
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المؤلفون: Jennifer E. Gallagher, Dorothy Kisielewski, John F. Dillon, Shaun V. Walsh, Diane Cassidy, David J. Harrison, Ritu Sharma, Tadashi Honda, John D. Hayes, Alison D. McNeilly, Michael L.J. Ashford, Albena T. Dinkova-Kostova, Rory J. McCrimmon
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)مصطلحات موضوعية: NQO1, NAD(P)H:quinone oxidoreductase 1, TNF-α, tumor necrosis factor-α, IRE1α, inositol requiring kinase-1α, SCAD, short-chain acyl-CoA dehydrogenase, C/EBP, CCAAT/enhancer-binding protein, PCR, polymerase chain reaction, UPR, unfolded protein response, 0302 clinical medicine, Fibrosis, MGPAT, mitochondrial glycerol-3-phosphate acetyltransferase, ATF4, activating transcription factor-4, DGAT2, diacylglycerol acyltransferase-2, LXRα, liver X receptor α, Glucose homeostasis, eIf2α, eukaryotic translation initiation factor 2A, IKK, IκB kinase, ACOT7, acetyl-CoA thioesterase 7, Original Research, TGFβ, transforming growth factor beta-1, SLC7A11, solute carrier family 7 member 11, GSSG, oxidized glutathione, MTTP, microsomal triglyceride transfer protein, NASH, Gastroenterology, TXN1, thioredoxin-1, 3. Good health, ChREBP, carbohydrate-responsive element-binding protein, 030220 oncology & carcinogenesis, NASH, nonalcoholic steatohepatitis, medicine.medical_specialty, PARP, poly ADP ribose polymerase, qRT-PCR, quantitative reverse transcriptase PCR, GSTM1, glutathione S-transferase Mu-1, GCLC, glutamate-cysteine ligase catalytic, Nrf2, ACACA, acetyl-CoA carboxylase alpha, 03 medical and health sciences, FXR, farnesoid X receptor, Nrf2, NF-E2 p45-related factor 2, COX2, cyclooxygenase-2, Keap1, Kelch-like ECH-associated protein-1, PPARα, peroxisome proliferator-activated receptor α, PTT, pyruvate tolerance test, HMOX1, heme oxygenase-1, RC, regular chow, p58IPK, p58 inhibitor of the PKR kinase, medicine.disease, TBE-31, 030104 developmental biology, Endocrinology, COL1A1, collagen, type I, alpha-1, Unfolded protein response, CAT, catalase, 0301 basic medicine, PDI, protein disulfide isomerase, GSH, reduced glutathione, FASN, fatty acid synthase, BCL-2, B-cell lymphoma, MPO, myeloperoxidase, AP-1, activator protein 1, DMSO, dimethyl sulfoxide, medicine.disease_cause, SHP, small heterodimer partner, CDDO, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid, CHOP, C/EBP homologous protein, TXNRD1, thioredoxin reductase-1, HF30Fr, high-fat diet with 30% fructose in drinking water, IκB, inhibitor of NF-κB, SFN, sulforaphane, ADRP, adipose differentiation-related protein, NAS, NAFLD activity score, GPX2, glutathione peroxidase-2, Chemistry, MCP-1, monocyte chemotactic protein-1, XBP1, X-box binding protein-1, SREBP-1c, sterol regulatory element-binding protein-1c, Lipogenesis, GTT, glucose tolerance test, PERK, PRK-like endoplasmic reticulum kinase, PTGR1, prostaglandin reductase-1, GSTA4, glutathione S-transferase Alpha-4, medicine.symptom, NAFLD, non-alcoholic fatty liver disease, α-SMA, alpha smooth muscle actin, ACOX2, acetyl-CoA oxidase 2, HFFr, high-fat diet with fructose in drinking water, NF-κB, nuclear factor-κB, GCLM, glutamate-cysteine ligase modifier, Inflammation, JNK1, c-Jun N-terminal kinase 1, CD36, cluster of differentiation 36, ER, endoplasmic reticulum, Insulin resistance, HF, high-fat, HF55Fr, high-fat diet with 55% fructose in drinking water, Internal medicine, ATF6, activating transcription factor-6, medicine, ApoB, apolipoprotein B, lcsh:RC799-869, CES1G, carboxylesterase 1g, ITT, insulin tolerance test, MCD, methionine- and choline-deficient, ACLY, ATP citrate lyase, Hepatology, SCD1, stearoyl-CoA desaturase-1, NOS2, nitric oxide synthase-2, PRDX6, peroxiredoxin 6, PPARγ, peroxisome proliferator-activated receptor γ, BIP, binding immunoglobulin protein, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, Steatosis, CPT1A, carnitine palmitoyltransferase 1a, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdd8de56b5ba950a8c970d72cce7012Test
https://doi.org/10.1016/j.jcmgh.2017.11.016Test