المؤلفون: Masaru Ishii, Junichi Kikuta, Atsunori Tsuchiya, Masaaki Takamura, Kenji Nakajima, Hara Yukio, Masahiro Ogawa, Suguru Takeuchi, Shunsuke Nojiri, Yuichi Kojima, Junji Yamashita, Shuji Terai, Takayuki Watanabe

المصدر: Regenerative Therapy, Vol 11, Iss, Pp 269-281 (2019)
Regenerative Therapy

مصطلحات موضوعية: 0301 basic medicine, Cirrhosis, ALP, Alkaline phosphatase, Adipose tissue, PGE2, Prostaglandin E2, Pharmacology, medicine.disease_cause, Prostaglandin E synthase, SOD, Superoxide dismutase, Cell therapy, hypoMSCs, MSCs cultured under hypoxic oxygen (5% O2) conditions, 0302 clinical medicine, norMSCs, MSCs cultured under normal oxygen (21% O2) conditions, Fibrosis, CAGE, Cap analysis of gene expression, Prostaglandin E2, LPS, Lipopolysaccharide, lcsh:R5-920, biology, HHSteC, Human Hepatic Stellate Cells, Chemistry, lcsh:Cytology, 8-OHdG, DNA 8-hydroxy-2’-deoxyguanosine, ALB, Albumin, id-BMM, Induced Bone Marrow Derived Macrophage, Original Article, PGE2, lcsh:Medicine (General), medicine.drug, T-Bil, Total bilirubin, Biomedical Engineering, Biomaterials, 03 medical and health sciences, ECM, Extracellular matrix, Hypoxic condition, medicine, lcsh:QH573-671, MDA, Malondialdehyde, LC, Liver cirrhosis, NASH, Non-alcoholic steatohepatitis, miR210, Mesenchymal stem cell, ALT, Alanine aminotransferase, MSCs, Mesenchymal stem cells, medicine.disease, 030104 developmental biology, Liver cirrhosis, biology.protein, Mesenchymal stem cells, PCR, Polymerase chain reaction, CCl4, Carbon tetrachloride, 030217 neurology & neurosurgery, Oxidative stress, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796000c604663d3d982bebac495f5eedTest
http://www.sciencedirect.com/science/article/pii/S2352320419300811Test

المؤلفون: Takayoshi Suganami, Shuji Terai, Shunsuke Nojiri, Masahiro Ogawa, Tomoaki Yoshida, Atsunori Tsuchiya, Suguru Takeuchi, Takayuki Watanabe, Yoshihiro Ogawa, Masaaki Takamura, Michiko Itoh

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 14, Iss, Pp 252-261 (2020)

مصطلحات موضوعية: 0301 basic medicine, NAFLD, non-alcoholic fatty liver disease, Cirrhosis, MC4R, melanocortin-4 receptor-deficient, Lipopolysaccharide, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, Biomedical Engineering, Adipose tissue, MSC, mesenchymal stem cell, Small extracellular vesicles, Pharmacology, hCLS, hepatic crown-like structure, Biomaterials, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, MCD, methionine-choline-deficient diet, Fibrosis, sEV, small extracellular vesicle, medicine, lcsh:QH573-671, Receptor, Non-alcoholic steatohepatitis, lcsh:R5-920, WD, Western diet, biology, business.industry, lcsh:Cytology, ND, normal diet, Mesenchymal stem cell, medicine.disease, 030104 developmental biology, chemistry, Alanine transaminase, biology.protein, Mesenchymal stem cells, Original Article, Steatohepatitis, business, lcsh:Medicine (General), HCC, hepatocellular carcinoma, T-bil, total bilirubin, T-cho, total cholesterol, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c605b87d1574bec9c086c0f3c9517bTest
https://pubmed.ncbi.nlm.nih.gov/32455155Test

المؤلفون: Yanyong Xu, Kavita Jadhav, Yingdong Zhu, Yuan-Yuan Li, Takhar Kasumov, Jiesi Xu, Yang Xu, Luciano Adorini, Yoon Kwang Lee, Yanqiao Zhang, Liya Yin

المصدر: Molecular Metabolism, Vol 9, Iss, Pp 131-140 (2018)
Molecular Metabolism

مصطلحات موضوعية: Male, 0301 basic medicine, Col1α1, collagen type 1 α1, NS, not significant, Receptors, Cytoplasmic and Nuclear, PPARγ, peroxisome proliferation-activated receptor γ, Receptors, G-Protein-Coupled, Mice, IL-1β, interleukin 1β, SHP, small heterodimer partner, α-Sma, alpha smooth muscle actin (α-Sma), HFD, high fat diet, Non-alcoholic Fatty Liver Disease, Tgfβ, transforming growth factor β, Receptor, TG, triglyceride, Bile acid, Chemistry, TGR5, GLP-1, glucagon-like peptide-1, Hep G2 Cells, Peroxisome, G protein-coupled bile acid receptor, 3. Good health, TNFα, tumor necrosis factor α, Pck1, phosphoenoylpyruvate carboxylase 1, TGR5, G protein coupled bile acid receptor (GPBAP), Lipogenesis, BA, bile acid, G6pc, glucose 6-phosphatase, Small heterodimer partner, Original Article, Agonist, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, lcsh:Internal medicine, Timp1, tissue inhibitor of metalloproteinase 1, medicine.drug_class, NASH, non-alcoholic steatohepatitis, Hypercholesterolemia, Diet, High-Fat, Bile Acids and Salts, 03 medical and health sciences, FXR, farnesoid X receptor, Farnesoid X receptor, NAFLD, Internal medicine, medicine, Animals, Humans, Obesity, lcsh:RC31-1245, Molecular Biology, CEBPα, CCAAT/enhancer-binding protein α, DIO, diet-induced obesity, Cell Biology, Atherosclerosis, Mice, Inbred C57BL, BAT, brown adipose tissue, 030104 developmental biology, Endocrinology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6f686d41c1a501b1cae42176973abbTest
http://www.sciencedirect.com/science/article/pii/S2212877817309195Test

المؤلفون: Elisabeth D. Galsgaard, Henrik D. Pedersen, Berit Østergaard Christoffersen, Merete Fredholm, Markus Latta, Dorte Holst, Susanna Cirera

المصدر: Journal of Clinical and Experimental Hepatology
Pedersen, H D, Galsgaard, E D, Christoffersen, B, Cirera, S, Holst, D, Fredholm, M & Latta, M 2020, ' NASH-inducing Diets in Göttingen Minipigs ', Journal of Clinical and Experimental Hepatology, vol. 10, no. 3, pp. 211-221 . https://doi.org/10.1016/j.jceh.2019.09.004Test

مصطلحات موضوعية: medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Porcine, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, GLDH, glutamate dehydrogenase, Choline, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, AST, aspartate transaminase, Internal medicine, Fatty liver, FFC, high-fat, fructose, cholesterol, Medicine, Animal model, amino acid defined high-fat diet (-S, with sucrose, Sirius Red, Hepatology, EDTA, ethylenediaminetetraacetic acid, ALP, alkaline phosphatase, business.industry, Cholesterol, GGT, gamma-glutamyltransferase, HE, hematoxylin and eosin, Fructose, medicine.disease, Endocrinology, chemistry, CD45, cluster of differentiation 45, 030220 oncology & carcinogenesis, Hepatic stellate cell, 030211 gastroenterology & hepatology, Original Article, F, with fructose), SMA, smooth muscle actin, CDAHFD, choline-deficient, Steatosis, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05e1f5726ee082ed2c5c2d742ea87d1Test
https://pubmed.ncbi.nlm.nih.gov/32405177Test

المؤلفون: Xuemei Wang, Wei Kong, Yuanyuan Pang, Lulu Sun, Huiying Liu, Bo Liu, Min Ye, Qing Wu, George Liu, Changtao Jiang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 702-710 (2019)

مصطلحات موضوعية: eWAT, epididymal white adipose tissue, Metabolic disorders, White adipose tissue, Gut flora, UPLC–MS/MS, ultra performance liquid chromatography–tandem mass spectrometry, 0302 clinical medicine, HFD, high fat diet, AST, aspartate transaminase, GCA, glycocholic acid, VLDL, very low-density lipoprotein, TβMCA, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, CAPE, caffeic acid phenethyl ester, TβMCA, tauro-β-muricholic acid, 0303 health sciences, CA, cholic acid, GCDCA, glycochenodeoxycholic acid, CYP7B1, biology, Bile acid, Chemistry, sWAT, subcutaneous white adipose tissue, FGF15/19, fibroblast growth factor 15/19, TG, triglycerides, CETP, cholesterol ester transfer protein, CYP7A1, cytochrome P450 family 7 subfamily A member 1, FXR, 030220 oncology & carcinogenesis, GTT, glucose tolerance test, BSH, bile acid hydrolase, CYP7B1, cytochrome P450 family 7 subfamily B member 1, medicine.medical_specialty, Original article, NAFLD, non-alcoholic fatty liver disease, PBA/SBA, primary bile acids to secondary bile acids, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TCA, taurocholic acid, Hamster, ALT, alanine amino-transferase, CYP8B1, cytochrome P450 family 8 subfamily B member 1, T2D, type 2 diabetes, Gut microbiota, AUC, area under curve, digestive system, CYP27A1, cytochrome P450 family 27 subfamily A member 1, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, 03 medical and health sciences, Insulin resistance, FXR, farnesoid X receptor, Internal medicine, medicine, ApoB, apolipoprotein B, 030304 developmental biology, ITT, insulin tolerance test, BAs, bile acids, lcsh:RM1-950, medicine.disease, biology.organism_classification, TC, total cholesterol, lcsh:Therapeutics. Pharmacology, Endocrinology, DCA, deoxycholic acid, H&E, hematoxylin and eosin, Farnesoid X receptor, Steatosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc312ddccc0b191b5f0414f6cd3240aTest
https://pubmed.ncbi.nlm.nih.gov/31384531Test

المؤلفون: Alexandra K. Leamy, Jamey D. Young, Robert A. Egnatchik, Masakazu Shiota, David A. Jacobson

المصدر: Molecular Metabolism

مصطلحات موضوعية: NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, SERCA, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, chemistry.chemical_element, Biology, Calcium, Mitochondrion, medicine.disease_cause, PA, palmitate, Calcium in biology, PI, propidium iodide, 03 medical and health sciences, chemistry.chemical_compound, H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate, ROS, reactive oxygen species, 0302 clinical medicine, BAPTA, Fatty liver, Internal medicine, CAC, citric acid cycle, FFA, free fatty acid, MUFA, monounsaturated fatty acid, medicine, Molecular Biology, MFA, metabolic flux analysis, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, APE, atom percent enrichment, Metabolic flux analysis, Cell Biology, SERCA, sarcoplasmic-endoplasmic reticulum calcium ATPase, 3. Good health, Endocrinology, chemistry, Lipotoxicity, Oxidative stress, OA, oleate, 030220 oncology & carcinogenesis, Original Article, BSA, bovine serum albumin, GC–MS, gas chromatography–mass spectrometry, ER stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8abb056af369ca34e6c97f53de9251Test

المؤلفون: Kasper W. ter Horst, Pim W. Gilijamse, Ahmet Demirkiran, Max Nieuwdorp, Joanne Verheij, Mariëtte T. Ackermans, Mireille J. Serlie, Bart A. van Wagensveld, Johannes A. Romijn, Mark A. Herman, Eleftheria Maratos-Flier

المساهمون: Graduate School, Other Research, Laboratory for Endocrinology, Pathology, General Internal Medicine, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology Endocrinology Metabolism, Vascular Medicine, Endocrinology, ACS - Diabetes & metabolism, Internal medicine

المصدر: Molecular metabolism, 6(11), 1493-1502. Elsevier GmbH
Molecular Metabolism, 6(11), 1493-1502. Elsevier GmbH
ter Horst, K W, Gilijamse, P W, Demirkiran, A, van Wagensveld, B A, Ackermans, M T, Verheij, J, Romijn, J A, Nieuwdorp, M, Maratos-Flier, E, Herman, M A & Serlie, M J 2017, ' The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans ', Molecular Metabolism, vol. 6, no. 11, pp. 1493-1502 . https://doi.org/10.1016/j.molmet.2017.08.014Test
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1493-1502 (2017)

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, FGF21, medicine.medical_treatment, Bariatric Surgery, FGF21, fibroblast growth factor 21, AUC, area under the curve, EGP, endogenous glucose production, chemistry.chemical_compound, 0302 clinical medicine, Weight loss, Insulin, Middle Aged, Fructose Intolerance, Obesity, Morbid, Liver, Female, Original Article, medicine.symptom, Rd, rate of disappearance, Adult, lcsh:Internal medicine, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ChREBP, carbohydrate response element-binding protein, GLP1, glucagon-like peptide 1, NASH, non-alcoholic steatohepatitis, Gastric Bypass, Translational study, 030209 endocrinology & metabolism, Fructose, Biology, 03 medical and health sciences, Insulin resistance, Internal medicine, Weight Loss, FFA, free fatty acid, medicine, Humans, Obesity, lcsh:RC31-1245, Carbohydrate-responsive element-binding protein, Molecular Biology, IQR, interquartile range, Ra, rate of appearance, Cell Biology, medicine.disease, Fatty Liver, Fibroblast Growth Factors, Glucose, 030104 developmental biology, Endocrinology, chemistry, Hyperinsulinemic-euglycemic clamp, Energy Metabolism, SD, standard deviation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2e659739c9955525826cd9525c9c29Test
https://pure.amc.nl/en/publications/the-fgf21-response-to-fructose-predicts-metabolic-health-and-persists-after-bariatric-surgery-in-obese-humansTest(1b1e6aa9-0f4a-4f37-b984-a10e3cf4e1ba).html