نتائج البحث

1

Hypoxia‐induced HIF‐1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF‐β‐dependent EMT

المؤلفون: Shuichi Hashimoto, Hiromitsu Morita, Akimitsu Hiraki, Shohei Yoshimoto, Fumie Tanaka

المصدر: Cancer Medicine, Vol 8, Iss 18, Pp 7822-7832 (2019)
Cancer Medicine

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Adolescent, Cell, medicine.disease_cause, lcsh:RC254-282, Malignant transformation, ameloblastoma, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Radiology, Nuclear Medicine and imaging, Epithelial–mesenchymal transition, Hypoxia, Ameloblastoma, Aged, Original Research, Cancer Biology, odontogenic tumors, transforming growth factor beta, epithelial‐mesenchymal transition, biology, Chemistry, Gene Expression Profiling, Zinc Finger E-box-Binding Homeobox 1, Transforming growth factor beta, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Immunohistochemistry, Cell Transformation, Neoplastic, 030104 developmental biology, HIF1A, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, Carcinogenesis, carcinogenesis, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d66ea9e982e349a0b95730d9a9531dTest
https://doi.org/10.1002/cam4.2667Test

2

MiR-18a-downregulated RORA inhibits the proliferation and tumorigenesis of glioma using the TNF-α-mediated NF-κB signaling pathway

المؤلفون: Zhitao Jing, Haiying Zhang, Dan Zou, Ye Zhang, Jiangfeng Hu, Dianqi Hou, Jinpeng Zhou, Junshuang Zhao, Long Li, Yang Jiang

المصدر: EBioMedicine
EBioMedicine, Vol 52, Iss, Pp-(2020)

مصطلحات موضوعية: 0301 basic medicine, Male, Research paper, Retinoic acid, lcsh:Medicine, medicine.disease_cause, RORA, chemistry.chemical_compound, Mice, 0302 clinical medicine, 3' Untranslated Regions, microRNA-18a, Orphan receptor, lcsh:R5-920, Cell Cycle, NF-kappa B, Nuclear Receptor Subfamily 1, Group F, Member 1, General Medicine, Glioma, Middle Aged, Prognosis, Immunohistochemistry, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, Female, RNA Interference, Signal transduction, lcsh:Medicine (General), Signal Transduction, Adult, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Neurosphere, Cell Line, Tumor, microRNA, medicine, Biomarkers, Tumor, Glioma stem cells, Animals, Humans, Viability assay, neoplasms, Aged, Tumor Necrosis Factor-alpha, Gene Expression Profiling, lcsh:R, Computational Biology, medicine.disease, nervous system diseases, Disease Models, Animal, MicroRNAs, 030104 developmental biology, chemistry, Tumorigenesis, Cancer research, Carcinogenesis, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3380a25215b81edc3a7afc40d2ddbbTest
http://europepmc.org/articles/PMC7016377Test

3

PD-L1 Status in Gastric Cancers, Association with the Transcriptional, Growth Factors, AKT/mTOR Components Change, and Autophagy Initiation

المؤلفون: Alexey Dobrodeev, Sergei Afanas’ev, L. V. Spirina, Dmitry Kostromitsky, Olga V Cheremisina, Alexandra Avgustinovich, Maxim Volkov

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 11176, p 11176 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20

مصطلحات موضوعية: Male, Programmed Cell Death 1 Receptor, Pembrolizumab, medicine.disease_cause, B7-H1 Antigen, Tumor Status, LC3B, Biology (General), Spectroscopy, biology, TOR Serine-Threonine Kinases, General Medicine, Middle Aged, Immunohistochemistry, Computer Science Applications, Gene Expression Regulation, Neoplastic, Chemistry, Intercellular Signaling Peptides and Proteins, Female, Microtubule-Associated Proteins, Signal Transduction, Adult, PD-L1, QH301-705.5, Article, Catalysis, Inorganic Chemistry, Young Adult, Stomach Neoplasms, growth factors, Autophagy, Biomarkers, Tumor, medicine, Humans, transcriptional factors, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, gastric cancers, business.industry, Organic Chemistry, Cancer, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, Cancer research, biology.protein, AKT/mTOR component, business, Carcinogenesis, Proto-Oncogene Proteins c-akt, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a688b59aeb6683480132d95296105a1dTest
https://doi.org/10.3390/ijms222011176Test

4

Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto’s Thyroiditis

المؤلفون: Axel De Greef, Chantal Daumerie, Marc de Bournonville, Michael Hepp, Marie-Christine Many, Benoît Lengelé, Marian Ludgate, Michel Mourad, Julie Craps, Virginie Joris, Alexis Werion, Catherine Behets, Christine de Ville de Goyet

المساهمون: UCL - SSS/IREC/MORF - Pôle de Morphologie, UCL - SSS/IREC/CHEX - Pôle de chirgurgie expérimentale et transplantation, UCL - SSS/IREC/FATH - Pôle de Pharmacologie et thérapeutique, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de chirurgie plastique, UCL - (SLuc) Service de soins intensifs, UCL - (SLuc) Service d'endocrinologie et de nutrition, UCL - (SLuc) Service de chirurgie et transplantation abdominale

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 3806, p 3806 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 8
International journal of molecular sciences, Vol. 22, no. 8, p. 3806 [1-17] (2021)

مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, 0301 basic medicine, endocrine system diseases, Thyroid Gland, Fluorescent Antibody Technique, Autoimmunity, Thyroid Function Tests, medicine.disease_cause, lcsh:Chemistry, Superoxide Dismutase-1, 0302 clinical medicine, Sirtuin 1, T-Lymphocyte Subsets, oxidative stress, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, Thymocytes, biology, Chemistry, Hashimoto’s thyroiditis, General Medicine, Middle Aged, Immunohistochemistry, Computer Science Applications, Vascular endothelial growth factor A, Catalase, 030220 oncology & carcinogenesis, NADPH Oxidase 2, Cytokines, Female, Adult, medicine.medical_specialty, HIF-1α, Hashimoto Disease, Peroxiredoxin 1, Models, Biological, Article, Catalysis, Autoimmune Diseases, NOX4, Inorganic Chemistry, Superoxide dismutase, Young Adult, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, medicine, Humans, Sirtuin1, Physical and Theoretical Chemistry, Molecular Biology, Reactive oxygen species, Organic Chemistry, Th1 Cells, Hypoxia-Inducible Factor 1, alpha Subunit, 030104 developmental biology, Endocrinology, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, biology.protein, Reactive Oxygen Species, Biomarkers, Oxidative stress