يعرض 1 - 10 نتائج من 21 نتيجة بحث عن '"Lactate dehydrogenase"', وقت الاستعلام: 0.79s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Genetic and Drug Inhibition of LDH-A: Effects on Murine Gliomas.

    المؤلفون: Maeda, Masatomo, Ko, Myat, Mane, Mayuresh M., Cohen, Ivan J., Shindo, Masahiro, Vemuri, Kiranmayi, Serganova, Inna, Blasberg, Ronald

    المصدر: Cancers; May2022, Vol. 14 Issue 9, pN.PAG-N.PAG, 20p

    مصطلحات موضوعية: EXPERIMENTAL design, ANIMAL experimentation, WESTERN immunoblotting, IMMUNOHISTOCHEMISTRY, GLIOMAS, GENE expression, MITOCHONDRIA, LACTATE dehydrogenase, MESSENGER RNA, CELL proliferation, RESEARCH funding, CELL lines, GLYCOLYSIS, ANIMALS, MICE

    النص الكامل

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  2. 2
    Cytoprotective Potential of Aged Garlic Extract (AGE) and Its Active Constituent, S-allyl-l-cysteine, in Presence of Carvedilol during Isoproterenol-Induced Myocardial Disturbance and Metabolic Derangements in Rats

    المؤلفون: Walaa F. Alsanie, Majid Alhomrani, Syed Mohammed Basheeruddin Asdaq, Abdulrahman Hadi Almutiri, Abdulhakeem S. Alamri, Obulesu Challa, Majed Sadun Alshammari

    المصدر: Molecules
    Molecules, Vol 26, Iss 3203, p 3203 (2021)
    Volume 26
    Issue 11

    مصطلحات موضوعية: myocardial disturbance, 030309 nutrition & dietetics, Thiobarbituric acid, Pharmaceutical Science, Organic chemistry, 030204 cardiovascular system & hematology, Antioxidants, Analytical Chemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, QD241-441, Drug Discovery, Creatine Kinase, MB Form, Carvedilol, 0303 health sciences, biology, Heart, Catalase, S-allyl cysteine, metabolic derangements, Chemistry (miscellaneous), Molecular Medicine, Female, medicine.drug, medicine.medical_specialty, S-Allyl cysteine, carvedilol, Thiobarbituric Acid Reactive Substances, Article, Superoxide dismutase, 03 medical and health sciences, Necrosis, cytoprotection, Lactate dehydrogenase, Internal medicine, aged garlic extract, medicine, TBARS, Animals, Cysteine, Physical and Theoretical Chemistry, Garlic, L-Lactate Dehydrogenase, isoproterenol, Plant Extracts, Superoxide Dismutase, Myocardium, Hemodynamics, Rats, Endocrinology, chemistry, biology.protein, Creatine kinase

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190076fd790f0d41b781531333ed5952Test
    http://europepmc.org/articles/PMC8198312Test


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  3. 3
    The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells

    المؤلفون: Edward V. Prochownik, Huabo Wang

    المصدر: Cells
    Cells, Vol 10, Iss 762, p 762 (2021)

    مصطلحات موضوعية: glutaminolysis, Embryonic Development, Review, Acetates, pyruvate carboxylase, malic enzyme, chemistry.chemical_compound, Lactate dehydrogenase, Neoplasms, Pyruvic Acid, Tumor Microenvironment, Animals, Humans, Glycolysis, lcsh:QH301-705.5, TCA cycle, Alanine, Glutaminolysis, Chemistry, lactate dehydrogenase, General Medicine, Pyruvate dehydrogenase complex, Pyruvate carboxylase, Biosynthetic Pathways, Citric acid cycle, Metabolic pathway, anaplerosis, lcsh:Biology (General), Biochemistry, Warburg effect

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e448397384cf79d3c9952a0f610085Test
    http://europepmc.org/articles/PMC8066905Test


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  4. 4
    CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production

    المؤلفون: Sophie Trefely, John Leferovich, Saba Ghassemi, Joshua D. Rabinowitz, Michael C. Milone, David Heo, Chong Xu, Roddy S. O’Connor, Carl H. June, Edmund K. Moon, Juan Carlos García-Cañaveras, Benjamin Philipson, Nathaniel W. Snyder

    المصدر: Cells
    Cells, Vol 10, Iss 2334, p 2334 (2021)
    Volume 10
    Issue 9

    مصطلحات موضوعية: Adult, Male, Lactobacillus brevis NADH oxidase, QH301-705.5, T-Lymphocytes, Levilactobacillus brevis, Receptors, Antigen, T-Cell, Oxidative phosphorylation, Mice, SCID, armor CAR T-cells, Article, LDHA, chemistry.chemical_compound, Mice, Adenosine Triphosphate, In vivo, Mice, Inbred NOD, Multienzyme Complexes, Lactate dehydrogenase, medicine, Animals, Humans, NADH, NADPH Oxidoreductases, Biology (General), chemistry.chemical_classification, biology, Lactobacillus brevis, General Medicine, Hypoxia (medical), biology.organism_classification, NAD, Electron transport chain, Enzyme, Biochemistry, chemistry, Female, NAD+ kinase, medicine.symptom, Oxidation-Reduction

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6dd535b72a88507d5a4eb743e90e60Test
    http://europepmc.org/articles/PMC8472053Test


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  5. 5
    Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl) Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A

    المؤلفون: Eman S. Nossier, Elsayed A. Elsayed, Abd El-Galil E. Amr, Ahmed M. Naglah, Mohamed El-Naggar, Randa E. Abdel Mageid

    المصدر: Molecules
    Molecules, Vol 25, Iss 5, p 1096 (2020)
    Volume 25
    Issue 5

    مصطلحات موضوعية: Pyridines, Pharmaceutical Science, 01 natural sciences, Analytical Chemistry, chemistry.chemical_compound, Mice, 0302 clinical medicine, Drug Discovery, chemistry.chemical_classification, education.field_of_study, Schiff base, Kinase, tetrapeptides, Amino acid, Neoplasm Proteins, Molecular Docking Simulation, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, MCF-7 Cells, Molecular Medicine, Schiff bases, Female, Stereochemistry, Lactate dehydrogenase A, p53 ubiquitination, Mice, Nude, Antineoplastic Agents, Hydrazide, Article, LDHA, lcsh:QD241-441, anticancer evaluation, 03 medical and health sciences, lcsh:Organic chemistry, Potency, Animals, Humans, Physical and Theoretical Chemistry, education, IC50, amino acids, Tetrapeptide, L-Lactate Dehydrogenase, 010405 organic chemistry, Organic Chemistry, molecular docking, Neoplasms, Experimental, 0104 chemical sciences, chemistry, Drug Screening Assays, Antitumor, Peptides

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc8ae17812806e3f112149b89567edaTest
    http://europepmc.org/articles/PMC7179198Test


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  6. 6
    Rethinking the Citric Acid Cycle: Connecting Pyruvate Carboxylase and Citrate Synthase to the Flow of Energy and Material

    المؤلفون: Graeme S. Cottrell, Dirk Roosterman

    المصدر: International Journal of Molecular Sciences
    International Journal of Molecular Sciences, Vol 22, Iss 604, p 604 (2021)

    مصطلحات موضوعية: Monocarboxylic Acid Transporters, memory formation, Citric Acid Cycle, oxidative phosphorylation, malic acid, Review, Citrate (si)-Synthase, Catalysis, lcsh:Chemistry, Inorganic Chemistry, chemistry.chemical_compound, Oxaloacetic acid, succinic acid, Citrate synthase, Animals, Humans, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Pyruvate Carboxylase, biology, exercise, L-Lactate Dehydrogenase, Symporters, Organic Chemistry, General Medicine, Computer Science Applications, Lactic acid, Pyruvate carboxylase, Citric acid cycle, lcsh:Biology (General), lcsh:QD1-999, chemistry, Biochemistry, Succinic acid, biology.protein, Malic acid, Pyruvic acid, Protons

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6289e68a8d8bef591b9db4e86d83641aTest
    http://europepmc.org/articles/PMC7827294Test


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  7. 7
    Inflammasome Activation Induced by a Snake Venom Lys49-Phospholipase A2 Homologue

    المؤلفون: Weverson Luciano Pires, Juliana P. Zuliani, Mauro Valentino Paloschi, Jéssica Amaral Lopes, Jaína Rodrigues Evangelista, Charles Nunes Boeno, Andreimar M. Soares, Sulamita da Silva Setúbal

    المصدر: Toxins
    Volume 12
    Issue 1
    Toxins, Vol 12, Iss 1, p 22 (2019)

    مصطلحات موضوعية: Male, muscle, Inflammasomes, Health, Toxicology and Mutagenesis, Interleukin-1beta, lcsh:Medicine, Lys49-PLA2, Venom, Inflammation, Phospholipase, Toxicology, complex mixtures, Article, 03 medical and health sciences, Mice, Necrosis, Phospholipase A2, inflammasome, Crotalid Venoms, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Animals, Bothrops, Receptor, Muscle, Skeletal, Creatine Kinase, 030304 developmental biology, snake venom, 0303 health sciences, biology, L-Lactate Dehydrogenase, Chemistry, lcsh:R, 030302 biochemistry & molecular biology, Caspase 1, Inflammasome, Molecular biology, Phospholipases A2, Snake venom, biology.protein, Liberation, lipids (amino acids, peptides, and proteins), Receptors, Purinergic P2X7, medicine.symptom, medicine.drug

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b06b5e1c9dbc697913b5632621fce7Test
    http://europepmc.org/articles/PMC7020408Test


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  8. 8
    Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells

    المؤلفون: Alan S. Premasiri, Fernando G. Vieira, Monica Z. Wang, Anna L. Gill, Beth Levine

    المصدر: International Journal of Molecular Sciences
    Volume 20
    Issue 24

    مصطلحات موضوعية: amyotrophic lateral sclerosis, Cell, chemistry.chemical_compound, C9orf72, Cricetinae, ALS/FTD, Fluorescein isothiocyanate, Spectroscopy, Neurons, dipeptide repeat proteins, medicine.diagnostic_test, Cell Death, Chinese hamster ovary cell, poly-PR, Neurodegeneration, arginine-rich, neurodegeneration, FTD, Cell Differentiation, General Medicine, Dipeptides, Computer Science Applications, medicine.anatomical_structure, poly-GR, Fluorescein-5-isothiocyanate, CHO Cells, Biology, Arginine, Catalysis, Article, Flow cytometry, Inorganic Chemistry, Cricetulus, medicine, Animals, Physical and Theoretical Chemistry, Molecular Biology, Cell Proliferation, L-Lactate Dehydrogenase, Organic Chemistry, medicine.disease, Molecular biology, Mice, Inbred C57BL, chemistry, Animals, Newborn, Cell culture, ALS, Trinucleotide repeat expansion

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bf48f73dc9925ce9cf8d0019e56f59Test
    http://europepmc.org/articles/PMC6941034Test


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  9. 9
    Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of Euphorbia peplus Methanolic Extract in Rats

    المؤلفون: Mohamed Abdo Nassan, Khaled Ben Issa, Abdelkarim Sasi, Adil Aldhahrani, Gamal A. Salem, Yasmina M. Abd-Elhakim, Amany Abdel-Rahman Mohamed

    المصدر: Toxins
    Toxins, Vol 11, Iss 11, p 642 (2019)
    Volume 11
    Issue 11

    مصطلحات موضوعية: Male, Cell Survival, Health, Toxicology and Mutagenesis, Aspartate transaminase, lcsh:Medicine, Pharmacology, Toxicology, Creatine, anticancer, Kidney, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Euphorbia peplus, In vivo, Euphorbia, Lactate dehydrogenase, medicine, Animals, Computer Simulation, Rats, Wistar, Linolenate, 030304 developmental biology, 0303 health sciences, Creatinine, biology, euphorbia peplus, Plant Extracts, Myocardium, lcsh:R, apoptosis, di-(2-ethylhexyl) phthalate, MDM2-p53, Heart, Proto-Oncogene Proteins c-mdm2, Rats, Molecular Docking Simulation, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, biology.protein, Creatine kinase, Tumor Suppressor Protein p53, Biomarkers

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eba02fc325f735540460f0919dbf9b5Test
    http://europepmc.org/articles/PMC6891376Test


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  10. 10
    In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung

    المؤلفون: Satyan Lakshminrusimha, Sara K. Berkelhamer, Maciej L. Goniewicz, Sylvia F. Gugino, Noel J. Leigh, Justin Helman

    المصدر: International Journal of Environmental Research and Public Health
    International Journal of Environmental Research and Public Health, Vol 16, Iss 19, p 3635 (2019)
    International journal of environmental research and public health, vol 16, iss 19
    Volume 16
    Issue 19

    مصطلحات موضوعية: Health, Toxicology and Mutagenesis, lcsh:Medicine, Pharmacology, Electronic Nicotine Delivery Systems, Toxicology, Fetal Development, chemistry.chemical_compound, 0302 clinical medicine, Smooth Muscle, 2.2 Factors relating to the physical environment, immature lung, 030212 general & internal medicine, Aetiology, Lung, Pediatric, 0303 health sciences, Chemistry, food and beverages, electronic cigarette flavorings, Menthol, medicine.anatomical_structure, electronic cigarettes, Toxicity, Respiratory, Programmed cell death, Myocytes, Smooth Muscle, In Vitro Techniques, Pulmonary Artery, Article, 03 medical and health sciences, Lactate dehydrogenase, medicine.artery, Tobacco, Toxicity Tests, medicine, Animals, 030304 developmental biology, lung development, Fetus, Myocytes, Sheep, Tobacco Smoke and Health, lcsh:R, Public Health, Environmental and Occupational Health, toxicity, Newborn, In vitro, Flavoring Agents, Good Health and Well Being, Animals, Newborn, Pulmonary artery

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bb69c7e7531dac6fde3b4d7be3a865Test
    http://europepmc.org/articles/PMC6801380Test


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