دورية أكاديمية
Effect of 10-week supervised moderate-intensity intermittent vs. continuous aerobic exercise programs on vascular adhesion molecules in patients with heart failure
| العنوان: | Effect of 10-week supervised moderate-intensity intermittent vs. continuous aerobic exercise programs on vascular adhesion molecules in patients with heart failure |
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| المؤلفون: | Rota, Simin, Dursunoglu, Dursun, FındıkoÄŸlu, Gülin, Aksoy, Sibel, Ardıç, Füsun |
| بيانات النشر: | Lippincott Williams and Wilkins |
| سنة النشر: | 2015 |
| المجموعة: | Pamukkale University Repository / Pamukkale Üniversitesi Açık Erişim Arşivi |
| مصطلحات موضوعية: | NO, Cardiac rehabilitation, sICAM-1, sVCAM-1, brain natriuretic peptide, cell adhesion molecule, intercellular adhesion molecule 1, nitric oxide, peptide fragment, pro-brain natriuretic peptide (1-76), vascular cell adhesion molecule 1, adult, aged, blood, body composition, comparative study, controlled study, female, heart failure, heart stroke volume, human, kinesiotherapy, male, middle aged, pathophysiology, physiology, procedures, prospective study, quality of life, randomized controlled trial |
| الوصف: | Objective: Abnormal expression of cellular adhesion molecules may be related to endothelial dysfunction, a key feature in chronic heart failure. This study compares the effects of 10-wk supervised moderate-intensity continuous aerobic exercise (CAE) and intermittent aerobic exercise (IAE) programs on markers of endothelial damage, disease severity, functional and metabolic status, and quality-of-life in chronic heart failure patients. Design: Fifty-seven patients between 41 and 81 yrs with New York Heart Association class IIYIII chronic heart failure and with a left ventricular ejection fraction of 35%-55% were randomized into three groups: nonexercising control, CAE, and IAE, which exercised three times a week for 10 wks. Endothelial damage was assessed by serum markers of vascular cell adhesion molecule-1, serum intercellular adhesion molecule-1, and nitric oxide; disease severity was measured by left ventricular ejection fraction and N-terminal probrain natriuretic peptide; metabolic status was evaluated by body composition analysis and lipid profile levels; functional status was evaluated by cardiorespiratory exercise stress test and 6-min walking distance; quality-of-life was assessed with Left Ventricular Dysfunction-36 and Short-Form 36 questionnaires at the baseline and at the end of the 10th week. Results: Significant decreases in serum vascular cell adhesion molecule-1 or serum intercellular adhesion molecule-1 in IAE and CAE groups after training were found, respectively. Resting systolic and diastolic blood pressure, peak systolic and diastolic blood pressure, 6-min walking distance, and the mental health and vitality components of Short-Form 36 improved in the CAE group, whereas left ventricular ejection fraction and 6-min walking distance improved in the IAE group compared with the control group. Conclusions: Both moderate-intensity CAE and IAE programs significantly reduced serum markers of adhesion molecules and prevented the change in VOinf>2/inf> in patients with chronic heart failure. ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0894-9115 |
| العلاقة: | American Journal of Physical Medicine and Rehabilitation; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11499/10224Test; https://doi.org/10.1097/PHM.0000000000000306Test; 94; 10; 898; 911; 2-s2.0-84942017215; WOS:000370519300009 |
| DOI: | 10.1097/PHM.0000000000000306 |
| الإتاحة: | https://doi.org/10.1097/PHM.0000000000000306Test https://hdl.handle.net/11499/10224Test |
| حقوق: | none |
| رقم الانضمام: | edsbas.DDB51B65 |
| قاعدة البيانات: | BASE |
| تدمد: | 08949115 |
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| DOI: | 10.1097/PHM.0000000000000306 |