المؤلفون: Narendra S. Choudhary, Neeraj Saraf, Swapnil Dhampalwar, Arvinder S. Soin

المصدر: Journal of Clinical and Experimental Hepatology

مصطلحات موضوعية: NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ACLF, acute-on chronic liver failure, Cirrhosis, Coronavirus disease 2019 (COVID-19), liver diseases, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, medicine.medical_treatment, LFT, liver function tests, Review Article, AST, aspartate aminotransferase, Liver transplantation, LT, liver transplantation, Chronic liver disease, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Gastroenterology, MELD, model for end-stage liver disease, 03 medical and health sciences, 0302 clinical medicine, HCWs, health care workers, Internal medicine, medicine, Risk of mortality, ALI, acute liver injury, In patient, COVID-19, Coronavirus disease 2019, immunosuppression, Hepatology, SARS-CoV-2, business.industry, NASH, ACE, angiotensin converting enzyme related carboxypeptidase receptors, Immunosuppression, medicine.disease, Decompensated cirrhosis, mortality, HR, hazard ratio, 030220 oncology & carcinogenesis, CLD, chronic liver disease, 030211 gastroenterology & hepatology, business, OR, Odds ratio

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3c248e064d1e6f7878934db19f6d0fTest
https://doi.org/10.1016/j.jceh.2021.05.003Test

المؤلفون: Bilal Hameed, Neil Mehta, Amit G. Singal, R. Katie Kelley, Neehar D. Parikh

المصدر: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 8
Clinical Gastroenterology and Hepatology

مصطلحات موضوعية: PD-L1, programmed death ligand 1, medicine.medical_treatment, Liver transplantation, Systemic therapy, 0302 clinical medicine, Model for End-Stage Liver Disease, Pandemic, alpha-fetoprotein (AFP), HCC, CMS, Centers for Medicare and Medicaid services, Cancer, COVID-19, Coronavirus disease 2019, AFP, alpha-fetoprotein, Liver Disease, Liver Neoplasms, BCLC, Barcelona Clinic Liver Cancer, Gastroenterology, RETREAT, Risk estimation of tumor recurrence after liver transplantation, LRT, local regional therapy, VEGF, vascular endothelial growth factor, Local, HCV, hepatitis C virus, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Screening, 030211 gastroenterology & hepatology, alpha-Fetoproteins, Patient Safety, Alpha-Fetoprotein, Liver Cancer, medicine.medical_specialty, Carcinoma, Hepatocellular, CTP, Child-Turcotte-Pugh, NASH, non-alcoholic steatohepatitis, AFP, Clinical Sciences, Context (language use), LT, liver transplantation, Lower risk, Article, 03 medical and health sciences, Rare Diseases, SBRT, stereotactic body radiotherapy, Clinical Research, GALAD, gender, age, AFP-L3, AFP, and DCP, medicine, AFP-L3, lectin-reactive alpha-fetoprotein, Humans, DCP, des-gamma carboxyprothrombin, Intensive care medicine, Adverse effect, Pandemics, RCT, randomized control trial, UNOS, United Network for Organ Sharing, Gastroenterology & Hepatology, Hepatology, SARS-CoV-2, business.industry, screening, MELD, Model for End Stage Liver Disease, Prevention, Carcinoma, COVID-19, Evaluation of treatments and therapeutic interventions, Hepatocellular, medicine.disease, TACE, trans-arterial chemoembolization, Coronavirus, HBV, hepatitis B virus, Neoplasm Recurrence, Good Health and Well Being, Neoplasm Recurrence, Local, HCC, hepatocellular carcinoma, Digestive Diseases, business

وصف الملف: application/pdf

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https://doi.org/10.1016/j.cgh.2020.06.072Test

المؤلفون: Jie Li, Xiaoyun Zhu, Jie Zou, Hao Zhang, Dejuan Xiang, Ling-Yi Kong, Zhigui Su, Yanqiu Zhang

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1578-1591 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Hepatocellular carcinoma, NASH, non-alcoholic steatohepatitis, Proliferation, Fructose 1,6-bisphosphatase, RM1-950, Carbohydrate metabolism, LIX1L, Limb and CNS expressed 1 like, Metastasis, 03 medical and health sciences, 0302 clinical medicine, FBP1, CCl4, carbon tetrachloride, miRNA, microRNA, medicine, shRNA, short-hairpin RNA, General Pharmacology, Toxicology and Pharmaceutics, 030304 developmental biology, Glucose metabolism, 0303 health sciences, Gene knockdown, ECAR, extracellular acidification rate, biology, business.industry, Gluconeogenesis, Cell migration, medicine.disease, Seq, sequencing, LIX1L, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Original Article, miR-21-3p, Therapeutics. Pharmacology, HCC, hepatocellular carcinoma, Liver cancer, business, EMT, epithelial–mesenchymal transition, FBP1, fructose-1,6-bisphosphatase 1, DEN, diethylnitrosamine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c970bf879a240521753514a3be8c82cTest
https://doi.org/10.1016/j.apsb.2021.02.005Test

المؤلفون: Lorenz Balcar, Marta Tonon, Georg Semmler, Valeria Calvino, Lukas Hartl, Simone Incicco, Mathias Jachs, David Bauer, Benedikt Silvester Hofer, Carmine Gabriele Gambino, Antonio Accetta, Alessandra Brocca, Michael Trauner, Mattias Mandorfer, Salvatore Piano, Thomas Reiberger

المصدر: JHEP Reports. 4:100513

مصطلحات موضوعية: PVT, HE, international normalised ratio, Child–Pugh score, SHR, United Network for Organ Sharing model for end-stage liver disease (2016), LT, ACLF, Immunology and Allergy, model for end-stage liver disease, portal vein thrombosis, aSHR, HCC, Portal hypertension, TFS, Baveno, UNOS MELD (2016), liver transplantation, IQR, NASH, Gastroenterology, CI, hepatocellular carcinoma, Acute kidney injury, TIPS, non-alcoholic steatohepatitis, acute-on-chronic liver failure, Hepatic decompensation, INR, adjusted subdistribution hazard ratio, interquartile range, hepatic encephalopathy, HRS-AKI, NAFLD, transjugular intrahepatic portosystemic shunt, Internal Medicine, Spontaneous bacterial peritonitis, subdistribution hazard ratio, ICA, SBP, variceal bleeding, refractory ascites, Hepatology, ACLF, acute-on-chronic liver failure, CI, confidence interval, CPS, Child–Pugh score, HCC, hepatocellular carcinoma, HE, hepatic encephalopathy, HRS-AKI, hepatorenal syndrome–acute kidney injury, ICA, International Club of Ascites, INR, international normalised ratio, IQR, interquartile range, LT, liver transplantation, MELD, model for end-stage liver disease, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, PVT, portal vein thrombosis, RA, refractory ascites, SBP, spontaneous bacterial peritonitis, SHR, subdistribution hazard ratio, TFS, transplant-free survival, TIPS, transjugular intrahepatic portosystemic shunt, UNOS MELD (2016), United Network for Organ Sharing model for end-stage liver disease (2016), VB, variceal bleeding, aSHR, adjusted subdistribution hazard ratio, non-alcoholic fatty liver disease, transplant-free survival, MELD, VB, confidence interval, International Club of Ascites, hepatorenal syndrome–acute kidney injury, CPS, RA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf81a5f893918c40914501beaf552554Test
https://doi.org/10.1016/j.jhepr.2022.100513Test

المؤلفون: Mirella Pastore, Alessandra Caligiuri, Chiara Raggi, Nadia Navari, Benedetta Piombanti, Giovanni Di Maira, Elisabetta Rovida, Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Krista Rombouts, Salvatore Petta, Fabio Marra

المساهمون: Pastore, Mirella, Caligiuri, Alessandra, Raggi, Chiara, Navari, Nadia, Piombanti, Benedetta, Di Maira, Giovanni, Rovida, Elisabetta, Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Rombouts, Krista, Petta, Salvatore, Marra, Fabio

المصدر: JHEP Reports. 4:100444

مصطلحات موضوعية: Hepatology, CM, conditioned medium, ECM, extracellular matrix, Gas-6, Gas-6, growth arrest-specific gene 6, HSC(s), hepatic stellate cells, KC(s), Kupffer cell(s), M-CSF, macrophage colony-stimulating factor, M2c-like macrophages, MerTK, Myeloid-epithelial-reproductive tyrosine kinase, NAFLD, non-alcoholic fatty liver disease, NASH, NASH, non-alcoholic steatohepatitis, PMA, phorbol 12-myristate 13-acetate, TGFβ1, transforming growth factor-β1, THP-1, TIMP1, tissue inhibitor of metalloproteinase 1, VEGF-A, vascular endothelial growth factor-A, liver fibrosis, siRNA, small-interfering RNA, Gas-6, liver fibrosis, M2c-like macrophages, NASH, THP-1, Gastroenterology, Internal Medicine, Immunology and Allergy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4426fd2abba675fb27730b5800bb5ccTest
https://doi.org/10.1016/j.jhepr.2022.100444Test

المؤلفون: Carrie E. McCurdy, Kenneth N. Maclean, Paul Kievit, Bryan C. Bergman, Rachel C. Janssen, Peter R. Baker, Christopher M. Mulligan, Tyler Dean, Diana L. Takahashi, Travis Nemkov, Kjersti Aagaard, Hua Jiang, Stephanie R. Wesolowski, Angelo D'Alessandro, Jacob E. Friedman

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 25-41 (2018)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Steatosis, VIP, variable importance in projection, Hypoxemia, AUC, area under the curve, PC, phosphatidylcholine, 0302 clinical medicine, WSD, Western-style diet, Non-alcoholic Fatty Liver Disease, Pregnancy, Fetal programming, Hyperlipidemia, DAG, diacylglyceride, VLDL, very low-density lipoprotein, Hypoxia, 2. Zero hunger, TG, triglyceride, NEFA, non-esterified fatty acid, NHP, non-human primate, Fatty liver, 3. Good health, Liver, Lipotoxicity, CON, control, OB-WSD, Western-style diet induced obesity group, IV-GTT, intravenous glucose tolerance test, Prenatal Exposure Delayed Effects, Original Article, Female, Diet, Healthy, PLS-DA, partial least squares discriminant analysis, TCA, tricarboxylic acid cycle, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, medicine.medical_specialty, Offspring, NASH, non-alcoholic steatohepatitis, Citric Acid Cycle, Metabolomic, 030209 endocrinology & metabolism, DNL, de novo lipogenesis, TBARs, thiobarbituric acid reactive substances, OB-DR, diet reversal group, 03 medical and health sciences, Fetus, Internal medicine, medicine, TBARS, Animals, Obesity, AA, amino acid, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Gluconeogenesis, Maternal Nutritional Physiological Phenomena, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, Diet, Western, Macaca, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06dccd8288a52f01636dbe7fd72ba0fTest
https://doi.org/10.1016/j.molmet.2018.09.008Test

المؤلفون: Bruce R. Blazar, Gregory Miller, Wei Chen, Jing Liu, Melanie S. Nyuydzefe, Geoffrey R. Hill, Katharine M. Irvine, Michelle Melino, Wayne A. Schroder, Patrick Bertolino, Kelli P. A. MacDonald, Alexandra Zanin-Zhorov, Michele W.L. Teng, Christina Nalkurthi, Andrew D. Clouston

المصدر: JHEP Reports

مصطلحات موضوعية: pSTAT3, phosphorylated signal transducer and activator of transcription, STAT3, signal transducer and activator of transcription 3, medicine.medical_treatment, AST, aspartate aminotransferase, TGF-β, transforming growth factor-beta, Chronic liver disease, TNF, tumour necrosis factor, RORγt, RAR-related orphan receptor gamma, Fibrosis, Th17, T helper 17, Immunology and Allergy, Macrophage, BMDM, bone marrow-derived macrophages, pCofilin, phosphorylated cofilin, Gastroenterology, qRT-PCR, quantitative real-time PCR, HSC, hepatic stellate cell, ECM, extracellular matrix, MMP, matrix metalloproteinase, IL-17, Cytokine, LPS, lipopolysaccharide, medicine.symptom, GC, germinal centre, ROCK2, Rho-associated kinase 2, Research Article, ROCK2 Inhibitor KD025, NASH, non-alcoholic steatohepatitis, Liver fibrosis, α-SMA, alpha smooth muscle actin, IHC, immunohistochemical, Tfh, T follicular helper, Inflammation, Col1a2, collagen type α1, Bcl6, B-cell lymphoma 6, ROCK2, Immune system, ALT, alanine aminotransferase, Internal Medicine, medicine, DR, ductular reaction, B cells, cGVHD, chronic graft-vs-host disease, pMac, peritoneal macrophages, TAA, thioacetamide, Hepatology, business.industry, Macrophages, SR, Sirius red, medicine.disease, ROCK, Rho-associated coiled-coil forming protein kinases, RAR, retinoic acid receptor, CLD, chronic liver disease, Cancer research, Therapy, HCC, hepatocellular carcinoma, business, Hepatic fibrosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d909aee919cee8dee5b9a4e06674119fTest
https://doi.org/10.1016/j.jhepr.2021.100386Test

المؤلفون: Louise China, Nekisa Zakeri, Tu Vinh Long, Alexander A. Maini, Amit Patel, Thais Helena Tittanegro, Alastair O'Brien, Roel P.H. De Maeyer, Natalia Becares, Derek W. Gilroy, Lucy Ly

المصدر: JHEP Reports, Vol 3, Iss 6, Pp 100332-(2021)
JHEP Reports

مصطلحات موضوعية: Cirrhosis, TNF, Decompensated cirrhosis, RC799-869, cPGES, cytosolic PGE synthase, HPGD, 15-hydroxyprostaglandin dehydrogenase, Gastroenterology, Liver disease, MDMs, monocyte-derived macrophages, Microsomal PGE synthase 1, Ascites, LC-MS/MS, liquid chromatography-tandem mass spectrometry, CM, classical monocytes, Immunology and Allergy, MFI, mean fluorescence intensity, TNFα, tumour necrosis factor alpha, Whole blood, TIPS, transjugular intrahepatic portosystemic shunt insertion, EIA, enzyme immune assay, HLA DR, human leukocyte antigen – DR isotype, Diseases of the digestive system. Gastroenterology, Jaundice, sCD14, soluble CD14, medicine.anatomical_structure, CRP, C-reactive protein, LPS, lipopolysaccharide, lipids (amino acids, peptides, and proteins), medicine.symptom, Research Article, HVs, healthy volunteers, medicine.medical_specialty, LPS, CAID, cirrhosis-associated immune dysfunction, NASH, non-alcoholic steatohepatitis, mPGES1, microsomal PGE synthase 1, Cyclo-oxygenase 1, White blood cell, Internal medicine, PGE2, prostaglandin E2, Internal Medicine, medicine, Decompensation, FACS, polychromatic flow cytometric analysis, Hepatology, business.industry, Monocyte, HLA-DR, OPD, patients with refractory ascites attending hospital outpatient department for day case paracentesis, DSS, downstream synthases, medicine.disease, AD, acute decompensation, IL6, COX, cyclooxygenase, ACLF, acute-on-chronic liver failure, qPCR, quantitative PCR, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3389d2aeb9a6d0bb948f1425e23e31fcTest
https://doi.org/10.1016/j.jhepr.2021.100332Test

المؤلفون: Kathrin van Bremen, Christoph Boesecke, Jenny Bischoff, Carolynne Schwarze-Zander, Wenyi Gu, Jan-Christian Wasmuth, Jonel Trebicka, Leona Dold, Jürgen K. Rockstroh

المصدر: EClinicalMedicine, Vol 40, Iss, Pp 101116-(2021)
EClinicalMedicine
E Clinical Medicine part of the LANCET Discovery Science

مصطلحات موضوعية: Medicine (General), medicine.medical_specialty, Steatosis, TAF, tenofovir-alafenamid, BMI, body mass index, NASH, non-alcoholic steatohepatitis, FIB4, fibrosis-4, cART, AST, aspartate aminotransferase, APRI, AST to platelet ratio index, INSTI, integrase strand transfer inhibitors, TDF, Tenofovir disoproxilfumarate, Lower risk, PrEP, pre-exposure prophylaxis, Pre-exposure prophylaxis, R5-920, Internal medicine, medicine, PLHIV, people living with HIV, FAST, FibroScan-AST, Nafld, business.industry, Proportional hazards model, Fatty liver, Hiv, DAA, direct-acting antiviral, NAFLD, Non-alcoholic fatty liver disease, General Medicine, medicine.disease, Cap, Comorbidity, TE, transient elastography, CAP, controlled attenuation parameter, HCV, chronic hepatitis C, Transient elastography, business, Body mass index, ART, antiretroviral treatment, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c309e13de16a72b2c91a8b35344a42Test
https://doi.org/10.1016/j.eclinm.2021.101116Test

المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459Test