المؤلفون: Carrie E. McCurdy, Kenneth N. Maclean, Paul Kievit, Bryan C. Bergman, Rachel C. Janssen, Peter R. Baker, Christopher M. Mulligan, Tyler Dean, Diana L. Takahashi, Travis Nemkov, Kjersti Aagaard, Hua Jiang, Stephanie R. Wesolowski, Angelo D'Alessandro, Jacob E. Friedman

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 25-41 (2018)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Steatosis, VIP, variable importance in projection, Hypoxemia, AUC, area under the curve, PC, phosphatidylcholine, 0302 clinical medicine, WSD, Western-style diet, Non-alcoholic Fatty Liver Disease, Pregnancy, Fetal programming, Hyperlipidemia, DAG, diacylglyceride, VLDL, very low-density lipoprotein, Hypoxia, 2. Zero hunger, TG, triglyceride, NEFA, non-esterified fatty acid, NHP, non-human primate, Fatty liver, 3. Good health, Liver, Lipotoxicity, CON, control, OB-WSD, Western-style diet induced obesity group, IV-GTT, intravenous glucose tolerance test, Prenatal Exposure Delayed Effects, Original Article, Female, Diet, Healthy, PLS-DA, partial least squares discriminant analysis, TCA, tricarboxylic acid cycle, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, medicine.medical_specialty, Offspring, NASH, non-alcoholic steatohepatitis, Citric Acid Cycle, Metabolomic, 030209 endocrinology & metabolism, DNL, de novo lipogenesis, TBARs, thiobarbituric acid reactive substances, OB-DR, diet reversal group, 03 medical and health sciences, Fetus, Internal medicine, medicine, TBARS, Animals, Obesity, AA, amino acid, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Gluconeogenesis, Maternal Nutritional Physiological Phenomena, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, Diet, Western, Macaca, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06dccd8288a52f01636dbe7fd72ba0fTest
https://doi.org/10.1016/j.molmet.2018.09.008Test

المؤلفون: Kathrin van Bremen, Christoph Boesecke, Jenny Bischoff, Carolynne Schwarze-Zander, Wenyi Gu, Jan-Christian Wasmuth, Jonel Trebicka, Leona Dold, Jürgen K. Rockstroh

المصدر: EClinicalMedicine, Vol 40, Iss, Pp 101116-(2021)
EClinicalMedicine
E Clinical Medicine part of the LANCET Discovery Science

مصطلحات موضوعية: Medicine (General), medicine.medical_specialty, Steatosis, TAF, tenofovir-alafenamid, BMI, body mass index, NASH, non-alcoholic steatohepatitis, FIB4, fibrosis-4, cART, AST, aspartate aminotransferase, APRI, AST to platelet ratio index, INSTI, integrase strand transfer inhibitors, TDF, Tenofovir disoproxilfumarate, Lower risk, PrEP, pre-exposure prophylaxis, Pre-exposure prophylaxis, R5-920, Internal medicine, medicine, PLHIV, people living with HIV, FAST, FibroScan-AST, Nafld, business.industry, Proportional hazards model, Fatty liver, Hiv, DAA, direct-acting antiviral, NAFLD, Non-alcoholic fatty liver disease, General Medicine, medicine.disease, Cap, Comorbidity, TE, transient elastography, CAP, controlled attenuation parameter, HCV, chronic hepatitis C, Transient elastography, business, Body mass index, ART, antiretroviral treatment, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c309e13de16a72b2c91a8b35344a42Test
https://doi.org/10.1016/j.eclinm.2021.101116Test

المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459Test

المؤلفون: Taesik Gwag, Shuxia Wang, Eun Y. Lee, Dong Li, Raja Gopal Reddy Mooli, Sangderk Lee

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 1, Pp 100193-(2021)

مصطلحات موضوعية: HFD, high-fat diet, Cirrhosis, Th, T helper type, Macrophage, AST, aspartate aminotransferase, Chronic liver disease, α-SMA, smooth muscle actin, TNF, tumour necrosis factor, TSP1, TSP1, thrombospondin 1, DEG, differentially expressed gene, IL-, interleukin, Immunology and Allergy, Medicine, TGF, transforming growth factor, scRNA-seq, single-cell RNA sequencing, Liver injury, NAS, NAFLD activity score, Fatty liver, NASH, SMPDL3B, Gastroenterology, AMLN, amylin liver NASH, ASMase, acid sphingomyelinase, BMDM, bone marrow-derived macrophage, HSC, hepatic stellate cell, ECM, extracellular matrix, SMPDL3B, sphingomyelin phosphodiesterase acid-like 3B, LPS, lipopolysaccharide, Research Article, TLR, Toll-like receptor, GPI, glycosylphosphatidylinositol, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, NF-κB, nuclear factor-κB, KEGG, Kyoto Encyclopedia of Genes and Genomes, MP, mononuclear phagocyte, digestive system, Tsp1Δmɸ, macrophage-specific TSP1-knockout mice, Insulin resistance, NAFLD, ALT, alanine aminotransferase, Internal Medicine, KC, Kupffer cell, Tsp1Δadipo, adipocyte-specific TSP1-knockout mice, Obesity, lcsh:RC799-869, Hepatology, EC, endothelial cell, business.industry, nutritional and metabolic diseases, medicine.disease, digestive system diseases, LFD, low-fat diet, SREBP1c, sterol regulatory element-binding protein-1 c, Cancer research, Hepatic stellate cell, Tsp1fl/fl, TSP1 floxed mice, lcsh:Diseases of the digestive system. Gastroenterology, MDM, monocyte-derived macrophage, qPCR, quantitative PCR, Steatosis, Steatohepatitis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063dac1179b4deacdbae7ecdef605114Test
https://doi.org/10.1016/j.jhepr.2020.100193Test

المؤلفون: Adnan Said, Ahmed Akhter

المصدر: Annals of Hepatology, Vol 16, Iss 4, Pp 538-547 (2017)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, endocrine system diseases, medicine.medical_treatment, Specialties of internal medicine, Placebo, Gastroenterology, Antioxidants, Rosiglitazone, 03 medical and health sciences, NAFLD (Non Alcoholic Fatty Liver Disease), 0302 clinical medicine, Insulin resistance, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Humans, Hypoglycemic Agents, Vitamin E, Aged, Randomized Controlled Trials as Topic, NASH (Non Alcoholic Steatohepatitis), Chi-Square Distribution, Pioglitazone, Hepatology, business.industry, General Medicine, Middle Aged, medicine.disease, Metformin, Treatment Outcome, 030104 developmental biology, Liver, RC581-951, Female, Thiazolidinediones, 030211 gastroenterology & hepatology, Insulin Resistance, Steatosis, Steatohepatitis, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f3fe847018b38fc24c1fbb4ab37eb1Test
https://doi.org/10.5604/01.3001.0010.0284Test

المؤلفون: Kento Imajo, Masato Yoneda, Yuji Ogawa, Michihiro Iwaki, Satoru Saito, Eiji Sakai, Takashi Kobayashi, Takeharu Yamanaka, Anna Ozaki, Yasushi Honda, Takaomi Kessoku, Masataka Taguri, Tomoyuki Iwasaki, Takeo Kurihashi, Atsushi Nakajima

المصدر: Contemporary Clinical Trials Communications
Contemporary Clinical Trials Communications, Vol 17, Iss, Pp-(2020)

مصطلحات موضوعية: Hepatic steatosis, NAFLD, non-alcoholic fatty liver disease, PPS, per protocol set, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Tofogliflozin, jRCTs, the Japan Registry of Clinical Trials, Gastroenterology, Article, CRF, case report form, 03 medical and health sciences, chemistry.chemical_compound, Diabetes mellitus, 0302 clinical medicine, DM, diabetes mellitus, ALT, alanine aminotransferase, Internal medicine, Nonalcoholic fatty liver disease, medicine, Clinical endpoint, MRI-PDFF, magnetic resonance imaging-based proton density fat fraction, 030212 general & internal medicine, SPIRIT, the Standard Protocol Items: Recommendations for Interventional Trials, Pharmacology, lcsh:R5-920, Pioglitazone, business.industry, FAS, full analysis set, Fatty liver, General Medicine, MRI-Based proton density fat fraction, medicine.disease, chemistry, HbA1c, glycated hemoglobin, Steatosis, Metabolic syndrome, lcsh:Medicine (General), business, AE, adverse event, 030217 neurology & neurosurgery, Non-alcoholic fatty liver disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4349db9a590c012463642bea2025437cTest
https://doi.org/10.1016/j.conctc.2019.100516Test

المؤلفون: Ryan D. Welch, Thomas P. Burris, Kristine Griffett, Brent A. Neuschwander-Tetri, Colin A. Flaveny, Grant R. Kolar

المصدر: Molecular Metabolism, Vol 4, Iss 4, Pp 353-357 (2015)
Molecular Metabolism

مصطلحات موضوعية: lcsh:Internal medicine, medicine.medical_specialty, LXR, Liver-X-Receptor, NASH, non-alcoholic steatohepatitis, HTF, high trans-fat diet, Inflammation, Brief Communication, digestive system, Fibrosis, Internal medicine, medicine, Inverse agonist, lcsh:RC31-1245, Liver X receptor, Molecular Biology, business.industry, Lipogenesis, NASH, nutritional and metabolic diseases, NR, nuclear receptor, Cell Biology, medicine.disease, digestive system diseases, Endocrinology, Nuclear receptor, LXR, Steatosis, medicine.symptom, Steatohepatitis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88dd36f2d559f5bc8b84a3443c1ee6c9Test
https://doi.org/10.1016/j.molmet.2015.01.009Test