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1Macrophage MerTK promotes profibrogenic cross-talk with hepatic stellate cells via soluble mediators
المؤلفون: Mirella Pastore, Alessandra Caligiuri, Chiara Raggi, Nadia Navari, Benedetta Piombanti, Giovanni Di Maira, Elisabetta Rovida, Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Krista Rombouts, Salvatore Petta, Fabio Marra
المساهمون: Pastore, Mirella, Caligiuri, Alessandra, Raggi, Chiara, Navari, Nadia, Piombanti, Benedetta, Di Maira, Giovanni, Rovida, Elisabetta, Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Rombouts, Krista, Petta, Salvatore, Marra, Fabio
المصدر: JHEP Reports. 4:100444
مصطلحات موضوعية: Hepatology, CM, conditioned medium, ECM, extracellular matrix, Gas-6, Gas-6, growth arrest-specific gene 6, HSC(s), hepatic stellate cells, KC(s), Kupffer cell(s), M-CSF, macrophage colony-stimulating factor, M2c-like macrophages, MerTK, Myeloid-epithelial-reproductive tyrosine kinase, NAFLD, non-alcoholic fatty liver disease, NASH, NASH, non-alcoholic steatohepatitis, PMA, phorbol 12-myristate 13-acetate, TGFβ1, transforming growth factor-β1, THP-1, TIMP1, tissue inhibitor of metalloproteinase 1, VEGF-A, vascular endothelial growth factor-A, liver fibrosis, siRNA, small-interfering RNA, Gas-6, liver fibrosis, M2c-like macrophages, NASH, THP-1, Gastroenterology, Internal Medicine, Immunology and Allergy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4426fd2abba675fb27730b5800bb5ccTest
https://doi.org/10.1016/j.jhepr.2022.100444Test -
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المؤلفون: Bruce R. Blazar, Gregory Miller, Wei Chen, Jing Liu, Melanie S. Nyuydzefe, Geoffrey R. Hill, Katharine M. Irvine, Michelle Melino, Wayne A. Schroder, Patrick Bertolino, Kelli P. A. MacDonald, Alexandra Zanin-Zhorov, Michele W.L. Teng, Christina Nalkurthi, Andrew D. Clouston
المصدر: JHEP Reports
مصطلحات موضوعية: pSTAT3, phosphorylated signal transducer and activator of transcription, STAT3, signal transducer and activator of transcription 3, medicine.medical_treatment, AST, aspartate aminotransferase, TGF-β, transforming growth factor-beta, Chronic liver disease, TNF, tumour necrosis factor, RORγt, RAR-related orphan receptor gamma, Fibrosis, Th17, T helper 17, Immunology and Allergy, Macrophage, BMDM, bone marrow-derived macrophages, pCofilin, phosphorylated cofilin, Gastroenterology, qRT-PCR, quantitative real-time PCR, HSC, hepatic stellate cell, ECM, extracellular matrix, MMP, matrix metalloproteinase, IL-17, Cytokine, LPS, lipopolysaccharide, medicine.symptom, GC, germinal centre, ROCK2, Rho-associated kinase 2, Research Article, ROCK2 Inhibitor KD025, NASH, non-alcoholic steatohepatitis, Liver fibrosis, α-SMA, alpha smooth muscle actin, IHC, immunohistochemical, Tfh, T follicular helper, Inflammation, Col1a2, collagen type α1, Bcl6, B-cell lymphoma 6, ROCK2, Immune system, ALT, alanine aminotransferase, Internal Medicine, medicine, DR, ductular reaction, B cells, cGVHD, chronic graft-vs-host disease, pMac, peritoneal macrophages, TAA, thioacetamide, Hepatology, business.industry, Macrophages, SR, Sirius red, medicine.disease, ROCK, Rho-associated coiled-coil forming protein kinases, RAR, retinoic acid receptor, CLD, chronic liver disease, Cancer research, Therapy, HCC, hepatocellular carcinoma, business, Hepatic fibrosis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d909aee919cee8dee5b9a4e06674119fTest
https://doi.org/10.1016/j.jhepr.2021.100386Test -
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المؤلفون: Jérôme Boursier, Emmanuel Tsochatzis
المساهمون: Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)
المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100219. ⟨10.1016/j.jhepr.2020.100219⟩
JHEP Reportsمصطلحات موضوعية: Cirrhosis, Cost effectiveness, [SDV]Life Sciences [q-bio], NICE, National Institute of Clinical Excellence, Nice, Review, AST, aspartate aminotransferase, Disease, Patient pathway, ELF, enhanced liver fibrosis, 0302 clinical medicine, Immunology and Allergy, Medicine, NFS, NAFLD fibrosis score, ALD, alcohol-related liver disease, ComputingMilieux_MISCELLANEOUS, computer.programming_language, 0303 health sciences, NAS, NAFLD activity score, Case-finding, Fatty liver, Gastroenterology, Awareness, Primary care, TE, transient elastography, 3. Good health, Screening, FIB-4, 030211 gastroenterology & hepatology, Elastography, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Liver fibrosis, QALY, quality-adjusted life year, 03 medical and health sciences, ALT, alanine aminotransferase, Type 2 diabetes mellitus, NIT, non-invasive test, Internal Medicine, GP, general practitioner, FIB-4, fibrosis-4, Intensive care medicine, 030304 developmental biology, Hepatology, business.industry, Type 2 Diabetes Mellitus, T2DM, type 2 diabetes mellitus, medicine.disease, Quality-adjusted life year, Cost-effectiveness, Transient elastography, business, computer
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998a5dc5ae8854bb83716af6e6873dc7Test
https://doi.org/10.1016/j.jhepr.2020.100219Test -
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المؤلفون: Patrick Ingiliz, Wolf Peter Hofmann, Anna Schmidt, Kerstin Stein, Peter Buggisch, Lisa Schubert, Marion Muche, Frank Lammert, Stefan Zeuzem, G Felten, Renate Heyne, Jeannette Schwenzer, Johannes Wiegand, Nektarios Dikopoulos, Jörn M. Schattenberg, Thomas Berg, Heiner Wedemeyer
المصدر: JHEP Reports
JHEP Reports, Vol 2, Iss 6, Pp 100168-(2020)مصطلحات موضوعية: NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, BMI, body mass index, NASH, non-alcoholic steatohepatitis, Liver fibrosis, LSM, liver stiffness measurement, AST, aspartate aminotransferase, Liver disease, FLAG, Fatty Liver Assessment in Germany, NAFLD, ALT, alanine aminotransferase, Internal medicine, APRI, aspartate-aminotransferase-to-platelet ratio index, Internal Medicine, NAFL, non-alcoholic fatty liver, Immunology and Allergy, Medicine, ddc:610, Co-morbidities, lcsh:RC799-869, FIB-4, fibrosis-4, Disease burden, Hepatology, FAST, FibroScan-AST, GGT, gamma-glutamyltransferase, business.industry, Fatty liver, NASH, Gastroenterology, Real world, GLP-1, glucagon-like peptide-1, T2DM, type 2 diabetes mellitus, CVE, cardiovascular event, medicine.disease, Metabolic syndrome, Cohort, lcsh:Diseases of the digestive system. Gastroenterology, CAP, controlled attenuation parameter, Steatohepatitis, business, Body mass index, Research Article, Cohort study
وصف الملف: application/octet-stream
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0cf2c2668ef3cb25aeddbf47a72b83Test
https://doi.org/10.1016/j.jhepr.2020.100168Test