المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459Test

المؤلفون: Taesik Gwag, Shuxia Wang, Eun Y. Lee, Dong Li, Raja Gopal Reddy Mooli, Sangderk Lee

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 1, Pp 100193-(2021)

مصطلحات موضوعية: HFD, high-fat diet, Cirrhosis, Th, T helper type, Macrophage, AST, aspartate aminotransferase, Chronic liver disease, α-SMA, smooth muscle actin, TNF, tumour necrosis factor, TSP1, TSP1, thrombospondin 1, DEG, differentially expressed gene, IL-, interleukin, Immunology and Allergy, Medicine, TGF, transforming growth factor, scRNA-seq, single-cell RNA sequencing, Liver injury, NAS, NAFLD activity score, Fatty liver, NASH, SMPDL3B, Gastroenterology, AMLN, amylin liver NASH, ASMase, acid sphingomyelinase, BMDM, bone marrow-derived macrophage, HSC, hepatic stellate cell, ECM, extracellular matrix, SMPDL3B, sphingomyelin phosphodiesterase acid-like 3B, LPS, lipopolysaccharide, Research Article, TLR, Toll-like receptor, GPI, glycosylphosphatidylinositol, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, NF-κB, nuclear factor-κB, KEGG, Kyoto Encyclopedia of Genes and Genomes, MP, mononuclear phagocyte, digestive system, Tsp1Δmɸ, macrophage-specific TSP1-knockout mice, Insulin resistance, NAFLD, ALT, alanine aminotransferase, Internal Medicine, KC, Kupffer cell, Tsp1Δadipo, adipocyte-specific TSP1-knockout mice, Obesity, lcsh:RC799-869, Hepatology, EC, endothelial cell, business.industry, nutritional and metabolic diseases, medicine.disease, digestive system diseases, LFD, low-fat diet, SREBP1c, sterol regulatory element-binding protein-1 c, Cancer research, Hepatic stellate cell, Tsp1fl/fl, TSP1 floxed mice, lcsh:Diseases of the digestive system. Gastroenterology, MDM, monocyte-derived macrophage, qPCR, quantitative PCR, Steatosis, Steatohepatitis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063dac1179b4deacdbae7ecdef605114Test
https://doi.org/10.1016/j.jhepr.2020.100193Test

المؤلفون: Adnan Said, Ahmed Akhter

المصدر: Annals of Hepatology, Vol 16, Iss 4, Pp 538-547 (2017)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, endocrine system diseases, medicine.medical_treatment, Specialties of internal medicine, Placebo, Gastroenterology, Antioxidants, Rosiglitazone, 03 medical and health sciences, NAFLD (Non Alcoholic Fatty Liver Disease), 0302 clinical medicine, Insulin resistance, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Humans, Hypoglycemic Agents, Vitamin E, Aged, Randomized Controlled Trials as Topic, NASH (Non Alcoholic Steatohepatitis), Chi-Square Distribution, Pioglitazone, Hepatology, business.industry, General Medicine, Middle Aged, medicine.disease, Metformin, Treatment Outcome, 030104 developmental biology, Liver, RC581-951, Female, Thiazolidinediones, 030211 gastroenterology & hepatology, Insulin Resistance, Steatosis, Steatohepatitis, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f3fe847018b38fc24c1fbb4ab37eb1Test
https://doi.org/10.5604/01.3001.0010.0284Test

المؤلفون: Mayumi Nagashimada, Eric Mayoux, Naoto Nagata, Guanliang Chen, Liang Xu, Shuichi Kaneko, Yinhua Ni, Fen Zhuge, Tsuguhito Ota

المصدر: EBioMedicine
EBioMedicine, Vol 20, Iss C, Pp 137-149 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, FGF21, Macrophage, lcsh:Medicine, AST, aspartate aminotransferase, White adipose tissue, 030204 cardiovascular system & hematology, ATMs, adipose tissue macrophages, Brown adipose tissue, EGP, endogenous glucose production, Mice, 0302 clinical medicine, Glucosides, FACS, fluorescence-activated cell sorting, TBARS, thiobarbituric acid reactive substances, Empa, empagliflozin, RER, respiratory exchange ratio, Adiposity, lcsh:R5-920, Glucose tolerance test, medicine.diagnostic_test, NEFA, non-esterified fatty acid, Fatty Acids, CT, computed tomographic, WAT, white adipose tissue, DIO, high-fat-diet-induced obese, General Medicine, TG, triglycerides, Adipose Tissue, H&E, haematoxylin and eosin, GTT, glucose tolerance test, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Adipose tissue macrophages, Biology, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Insulin resistance, VCO2, carbon dioxide production, FGF21, fibroblast growth factor, Internal medicine, UCP1, uncoupling protein 1, medicine, Empagliflozin, Animals, Hypoglycemic Agents, Obesity, Benzhydryl Compounds, Muscle, Skeletal, Sodium-Glucose Transporter 2 Inhibitors, ITT, insulin tolerance test, VO2, oxygen consumption, Inflammation, Macrophages, lcsh:R, SGLT, sodium/glucose cotransporter, Sodium glucose cotransporter-2 inhibitor, Body Weight, Insulin tolerance test, ALT, Alanine aminotransferase, Energy metabolism, UGE, urinary glucose excretion, Macrophage Activation, medicine.disease, BAT, brown adipose tissue, TC, total cholesterol, Fatty Liver, AMPK, AMP-activated protein kinase, Glucose, 030104 developmental biology, Endocrinology, Insulin Resistance, LMs, liver macrophages, Diet-induced obese, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c85fd9e3671e9effaeef0acf4b89dd1Test
https://doi.org/10.1016/j.ebiom.2017.05.028Test