المؤلفون: Narendra S. Choudhary, Neeraj Saraf, Swapnil Dhampalwar, Arvinder S. Soin

المصدر: Journal of Clinical and Experimental Hepatology

مصطلحات موضوعية: NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ACLF, acute-on chronic liver failure, Cirrhosis, Coronavirus disease 2019 (COVID-19), liver diseases, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, medicine.medical_treatment, LFT, liver function tests, Review Article, AST, aspartate aminotransferase, Liver transplantation, LT, liver transplantation, Chronic liver disease, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Gastroenterology, MELD, model for end-stage liver disease, 03 medical and health sciences, 0302 clinical medicine, HCWs, health care workers, Internal medicine, medicine, Risk of mortality, ALI, acute liver injury, In patient, COVID-19, Coronavirus disease 2019, immunosuppression, Hepatology, SARS-CoV-2, business.industry, NASH, ACE, angiotensin converting enzyme related carboxypeptidase receptors, Immunosuppression, medicine.disease, Decompensated cirrhosis, mortality, HR, hazard ratio, 030220 oncology & carcinogenesis, CLD, chronic liver disease, 030211 gastroenterology & hepatology, business, OR, Odds ratio

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3c248e064d1e6f7878934db19f6d0fTest
https://doi.org/10.1016/j.jceh.2021.05.003Test

المؤلفون: Bilal Hameed, Neil Mehta, Amit G. Singal, R. Katie Kelley, Neehar D. Parikh

المصدر: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 8
Clinical Gastroenterology and Hepatology

مصطلحات موضوعية: PD-L1, programmed death ligand 1, medicine.medical_treatment, Liver transplantation, Systemic therapy, 0302 clinical medicine, Model for End-Stage Liver Disease, Pandemic, alpha-fetoprotein (AFP), HCC, CMS, Centers for Medicare and Medicaid services, Cancer, COVID-19, Coronavirus disease 2019, AFP, alpha-fetoprotein, Liver Disease, Liver Neoplasms, BCLC, Barcelona Clinic Liver Cancer, Gastroenterology, RETREAT, Risk estimation of tumor recurrence after liver transplantation, LRT, local regional therapy, VEGF, vascular endothelial growth factor, Local, HCV, hepatitis C virus, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Screening, 030211 gastroenterology & hepatology, alpha-Fetoproteins, Patient Safety, Alpha-Fetoprotein, Liver Cancer, medicine.medical_specialty, Carcinoma, Hepatocellular, CTP, Child-Turcotte-Pugh, NASH, non-alcoholic steatohepatitis, AFP, Clinical Sciences, Context (language use), LT, liver transplantation, Lower risk, Article, 03 medical and health sciences, Rare Diseases, SBRT, stereotactic body radiotherapy, Clinical Research, GALAD, gender, age, AFP-L3, AFP, and DCP, medicine, AFP-L3, lectin-reactive alpha-fetoprotein, Humans, DCP, des-gamma carboxyprothrombin, Intensive care medicine, Adverse effect, Pandemics, RCT, randomized control trial, UNOS, United Network for Organ Sharing, Gastroenterology & Hepatology, Hepatology, SARS-CoV-2, business.industry, screening, MELD, Model for End Stage Liver Disease, Prevention, Carcinoma, COVID-19, Evaluation of treatments and therapeutic interventions, Hepatocellular, medicine.disease, TACE, trans-arterial chemoembolization, Coronavirus, HBV, hepatitis B virus, Neoplasm Recurrence, Good Health and Well Being, Neoplasm Recurrence, Local, HCC, hepatocellular carcinoma, Digestive Diseases, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07686baa7bc3f15f14e5a0d806140ee4Test
https://doi.org/10.1016/j.cgh.2020.06.072Test

المؤلفون: Jie Li, Xiaoyun Zhu, Jie Zou, Hao Zhang, Dejuan Xiang, Ling-Yi Kong, Zhigui Su, Yanqiu Zhang

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1578-1591 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Hepatocellular carcinoma, NASH, non-alcoholic steatohepatitis, Proliferation, Fructose 1,6-bisphosphatase, RM1-950, Carbohydrate metabolism, LIX1L, Limb and CNS expressed 1 like, Metastasis, 03 medical and health sciences, 0302 clinical medicine, FBP1, CCl4, carbon tetrachloride, miRNA, microRNA, medicine, shRNA, short-hairpin RNA, General Pharmacology, Toxicology and Pharmaceutics, 030304 developmental biology, Glucose metabolism, 0303 health sciences, Gene knockdown, ECAR, extracellular acidification rate, biology, business.industry, Gluconeogenesis, Cell migration, medicine.disease, Seq, sequencing, LIX1L, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Original Article, miR-21-3p, Therapeutics. Pharmacology, HCC, hepatocellular carcinoma, Liver cancer, business, EMT, epithelial–mesenchymal transition, FBP1, fructose-1,6-bisphosphatase 1, DEN, diethylnitrosamine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c970bf879a240521753514a3be8c82cTest
https://doi.org/10.1016/j.apsb.2021.02.005Test

المؤلفون: Carrie E. McCurdy, Kenneth N. Maclean, Paul Kievit, Bryan C. Bergman, Rachel C. Janssen, Peter R. Baker, Christopher M. Mulligan, Tyler Dean, Diana L. Takahashi, Travis Nemkov, Kjersti Aagaard, Hua Jiang, Stephanie R. Wesolowski, Angelo D'Alessandro, Jacob E. Friedman

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 25-41 (2018)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Steatosis, VIP, variable importance in projection, Hypoxemia, AUC, area under the curve, PC, phosphatidylcholine, 0302 clinical medicine, WSD, Western-style diet, Non-alcoholic Fatty Liver Disease, Pregnancy, Fetal programming, Hyperlipidemia, DAG, diacylglyceride, VLDL, very low-density lipoprotein, Hypoxia, 2. Zero hunger, TG, triglyceride, NEFA, non-esterified fatty acid, NHP, non-human primate, Fatty liver, 3. Good health, Liver, Lipotoxicity, CON, control, OB-WSD, Western-style diet induced obesity group, IV-GTT, intravenous glucose tolerance test, Prenatal Exposure Delayed Effects, Original Article, Female, Diet, Healthy, PLS-DA, partial least squares discriminant analysis, TCA, tricarboxylic acid cycle, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, medicine.medical_specialty, Offspring, NASH, non-alcoholic steatohepatitis, Citric Acid Cycle, Metabolomic, 030209 endocrinology & metabolism, DNL, de novo lipogenesis, TBARs, thiobarbituric acid reactive substances, OB-DR, diet reversal group, 03 medical and health sciences, Fetus, Internal medicine, medicine, TBARS, Animals, Obesity, AA, amino acid, lcsh:RC31-1245, Molecular Biology, Triglycerides, business.industry, Gluconeogenesis, Maternal Nutritional Physiological Phenomena, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, Diet, Western, Macaca, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06dccd8288a52f01636dbe7fd72ba0fTest
https://doi.org/10.1016/j.molmet.2018.09.008Test

المؤلفون: Bruce R. Blazar, Gregory Miller, Wei Chen, Jing Liu, Melanie S. Nyuydzefe, Geoffrey R. Hill, Katharine M. Irvine, Michelle Melino, Wayne A. Schroder, Patrick Bertolino, Kelli P. A. MacDonald, Alexandra Zanin-Zhorov, Michele W.L. Teng, Christina Nalkurthi, Andrew D. Clouston

المصدر: JHEP Reports

مصطلحات موضوعية: pSTAT3, phosphorylated signal transducer and activator of transcription, STAT3, signal transducer and activator of transcription 3, medicine.medical_treatment, AST, aspartate aminotransferase, TGF-β, transforming growth factor-beta, Chronic liver disease, TNF, tumour necrosis factor, RORγt, RAR-related orphan receptor gamma, Fibrosis, Th17, T helper 17, Immunology and Allergy, Macrophage, BMDM, bone marrow-derived macrophages, pCofilin, phosphorylated cofilin, Gastroenterology, qRT-PCR, quantitative real-time PCR, HSC, hepatic stellate cell, ECM, extracellular matrix, MMP, matrix metalloproteinase, IL-17, Cytokine, LPS, lipopolysaccharide, medicine.symptom, GC, germinal centre, ROCK2, Rho-associated kinase 2, Research Article, ROCK2 Inhibitor KD025, NASH, non-alcoholic steatohepatitis, Liver fibrosis, α-SMA, alpha smooth muscle actin, IHC, immunohistochemical, Tfh, T follicular helper, Inflammation, Col1a2, collagen type α1, Bcl6, B-cell lymphoma 6, ROCK2, Immune system, ALT, alanine aminotransferase, Internal Medicine, medicine, DR, ductular reaction, B cells, cGVHD, chronic graft-vs-host disease, pMac, peritoneal macrophages, TAA, thioacetamide, Hepatology, business.industry, Macrophages, SR, Sirius red, medicine.disease, ROCK, Rho-associated coiled-coil forming protein kinases, RAR, retinoic acid receptor, CLD, chronic liver disease, Cancer research, Therapy, HCC, hepatocellular carcinoma, business, Hepatic fibrosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d909aee919cee8dee5b9a4e06674119fTest
https://doi.org/10.1016/j.jhepr.2021.100386Test

المؤلفون: Louise China, Nekisa Zakeri, Tu Vinh Long, Alexander A. Maini, Amit Patel, Thais Helena Tittanegro, Alastair O'Brien, Roel P.H. De Maeyer, Natalia Becares, Derek W. Gilroy, Lucy Ly

المصدر: JHEP Reports, Vol 3, Iss 6, Pp 100332-(2021)
JHEP Reports

مصطلحات موضوعية: Cirrhosis, TNF, Decompensated cirrhosis, RC799-869, cPGES, cytosolic PGE synthase, HPGD, 15-hydroxyprostaglandin dehydrogenase, Gastroenterology, Liver disease, MDMs, monocyte-derived macrophages, Microsomal PGE synthase 1, Ascites, LC-MS/MS, liquid chromatography-tandem mass spectrometry, CM, classical monocytes, Immunology and Allergy, MFI, mean fluorescence intensity, TNFα, tumour necrosis factor alpha, Whole blood, TIPS, transjugular intrahepatic portosystemic shunt insertion, EIA, enzyme immune assay, HLA DR, human leukocyte antigen – DR isotype, Diseases of the digestive system. Gastroenterology, Jaundice, sCD14, soluble CD14, medicine.anatomical_structure, CRP, C-reactive protein, LPS, lipopolysaccharide, lipids (amino acids, peptides, and proteins), medicine.symptom, Research Article, HVs, healthy volunteers, medicine.medical_specialty, LPS, CAID, cirrhosis-associated immune dysfunction, NASH, non-alcoholic steatohepatitis, mPGES1, microsomal PGE synthase 1, Cyclo-oxygenase 1, White blood cell, Internal medicine, PGE2, prostaglandin E2, Internal Medicine, medicine, Decompensation, FACS, polychromatic flow cytometric analysis, Hepatology, business.industry, Monocyte, HLA-DR, OPD, patients with refractory ascites attending hospital outpatient department for day case paracentesis, DSS, downstream synthases, medicine.disease, AD, acute decompensation, IL6, COX, cyclooxygenase, ACLF, acute-on-chronic liver failure, qPCR, quantitative PCR, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3389d2aeb9a6d0bb948f1425e23e31fcTest
https://doi.org/10.1016/j.jhepr.2021.100332Test

المؤلفون: Kathrin van Bremen, Christoph Boesecke, Jenny Bischoff, Carolynne Schwarze-Zander, Wenyi Gu, Jan-Christian Wasmuth, Jonel Trebicka, Leona Dold, Jürgen K. Rockstroh

المصدر: EClinicalMedicine, Vol 40, Iss, Pp 101116-(2021)
EClinicalMedicine
E Clinical Medicine part of the LANCET Discovery Science

مصطلحات موضوعية: Medicine (General), medicine.medical_specialty, Steatosis, TAF, tenofovir-alafenamid, BMI, body mass index, NASH, non-alcoholic steatohepatitis, FIB4, fibrosis-4, cART, AST, aspartate aminotransferase, APRI, AST to platelet ratio index, INSTI, integrase strand transfer inhibitors, TDF, Tenofovir disoproxilfumarate, Lower risk, PrEP, pre-exposure prophylaxis, Pre-exposure prophylaxis, R5-920, Internal medicine, medicine, PLHIV, people living with HIV, FAST, FibroScan-AST, Nafld, business.industry, Proportional hazards model, Fatty liver, Hiv, DAA, direct-acting antiviral, NAFLD, Non-alcoholic fatty liver disease, General Medicine, medicine.disease, Cap, Comorbidity, TE, transient elastography, CAP, controlled attenuation parameter, HCV, chronic hepatitis C, Transient elastography, business, Body mass index, ART, antiretroviral treatment, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c309e13de16a72b2c91a8b35344a42Test
https://doi.org/10.1016/j.eclinm.2021.101116Test

المؤلفون: Anika Nier, Ina Bergheim, Amélia Camarinha-Silva, Cheng Jun Jin, Annette Brandt, Anja Baumann, Angélica Hernández-Arriaga, Dragana Rajcic, Victor Sánchez, Finn Jung

المصدر: Redox Biology
Redox Biology, Vol 41, Iss, Pp 101879-(2021)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), F, fructose, Arginine, Clinical Biochemistry, AST, aspartate aminotransferase, Biochemistry, Mice, AUC, area under the curve, NOHA, N(ω)-hydroxy-nor-l-arginine, Liver disease, chemistry.chemical_compound, PCR, polymerase chain reaction, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, ARG2, arginase 2, 3-NT, 3-nitrotyrosine, Citrulline, Biology (General), NAS, NAFLD activity score, Fatty liver, FFC, fat-, fructose- and cholesterol-rich diet, L-Cit, l-citrulline, Arginase, medicine.anatomical_structure, Liver, iNOS, inducible nitric oxide synthase, Female, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, QH301-705.5, C, control diet, NASH, non-alcoholic steatohepatitis, TNFα, tumor necrosis factor alpha, Intestinal permeability, Diet, High-Fat, SEM, standard error of the mean, NO, 03 medical and health sciences, R5-920, Tlr4, toll-like receptor 4, 4-HNE, 4-hydroxynonenal, ALT, alanine aminotransferase, Internal medicine, medicine, Animals, Hepatic inflammation, Gpr41, G-protein-coupled receptor 41, NO, nitric oxide, business.industry, Bacterial endotoxin, Organic Chemistry, E%, percentage of energy, medicine.disease, ZO-1, zonula occludens 1, Small intestine, GTT, glucose-tolerance-test, Mice, Inbred C57BL, Toll-Like Receptor 4, 030104 developmental biology, Endocrinology, chemistry, Dietary Supplements, Myd88, myeloid differentiation primary response 88, Gpr43, G-protein-coupled receptor 43, Steatohepatitis, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c29ebb68a39a4a69ad56089e73e70eTest
https://doi.org/10.1016/j.redox.2021.101879Test

المؤلفون: Jérôme Boursier, Emmanuel Tsochatzis

المساهمون: Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)

المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100219. ⟨10.1016/j.jhepr.2020.100219⟩
JHEP Reports

مصطلحات موضوعية: Cirrhosis, Cost effectiveness, [SDV]Life Sciences [q-bio], NICE, National Institute of Clinical Excellence, Nice, Review, AST, aspartate aminotransferase, Disease, Patient pathway, ELF, enhanced liver fibrosis, 0302 clinical medicine, Immunology and Allergy, Medicine, NFS, NAFLD fibrosis score, ALD, alcohol-related liver disease, ComputingMilieux_MISCELLANEOUS, computer.programming_language, 0303 health sciences, NAS, NAFLD activity score, Case-finding, Fatty liver, Gastroenterology, Awareness, Primary care, TE, transient elastography, 3. Good health, Screening, FIB-4, 030211 gastroenterology & hepatology, Elastography, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Liver fibrosis, QALY, quality-adjusted life year, 03 medical and health sciences, ALT, alanine aminotransferase, Type 2 diabetes mellitus, NIT, non-invasive test, Internal Medicine, GP, general practitioner, FIB-4, fibrosis-4, Intensive care medicine, 030304 developmental biology, Hepatology, business.industry, Type 2 Diabetes Mellitus, T2DM, type 2 diabetes mellitus, medicine.disease, Quality-adjusted life year, Cost-effectiveness, Transient elastography, business, computer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998a5dc5ae8854bb83716af6e6873dc7Test
https://doi.org/10.1016/j.jhepr.2020.100219Test

المؤلفون: Taesik Gwag, Shuxia Wang, Eun Y. Lee, Dong Li, Raja Gopal Reddy Mooli, Sangderk Lee

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 1, Pp 100193-(2021)

مصطلحات موضوعية: HFD, high-fat diet, Cirrhosis, Th, T helper type, Macrophage, AST, aspartate aminotransferase, Chronic liver disease, α-SMA, smooth muscle actin, TNF, tumour necrosis factor, TSP1, TSP1, thrombospondin 1, DEG, differentially expressed gene, IL-, interleukin, Immunology and Allergy, Medicine, TGF, transforming growth factor, scRNA-seq, single-cell RNA sequencing, Liver injury, NAS, NAFLD activity score, Fatty liver, NASH, SMPDL3B, Gastroenterology, AMLN, amylin liver NASH, ASMase, acid sphingomyelinase, BMDM, bone marrow-derived macrophage, HSC, hepatic stellate cell, ECM, extracellular matrix, SMPDL3B, sphingomyelin phosphodiesterase acid-like 3B, LPS, lipopolysaccharide, Research Article, TLR, Toll-like receptor, GPI, glycosylphosphatidylinositol, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, NF-κB, nuclear factor-κB, KEGG, Kyoto Encyclopedia of Genes and Genomes, MP, mononuclear phagocyte, digestive system, Tsp1Δmɸ, macrophage-specific TSP1-knockout mice, Insulin resistance, NAFLD, ALT, alanine aminotransferase, Internal Medicine, KC, Kupffer cell, Tsp1Δadipo, adipocyte-specific TSP1-knockout mice, Obesity, lcsh:RC799-869, Hepatology, EC, endothelial cell, business.industry, nutritional and metabolic diseases, medicine.disease, digestive system diseases, LFD, low-fat diet, SREBP1c, sterol regulatory element-binding protein-1 c, Cancer research, Hepatic stellate cell, Tsp1fl/fl, TSP1 floxed mice, lcsh:Diseases of the digestive system. Gastroenterology, MDM, monocyte-derived macrophage, qPCR, quantitative PCR, Steatosis, Steatohepatitis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063dac1179b4deacdbae7ecdef605114Test
https://doi.org/10.1016/j.jhepr.2020.100193Test