التفاصيل البيبلوغرافية
| العنوان: |
Migraine Aura: A Knockin Mouse with a Knockout Message |
| المؤلفون: |
Goadsby, Peter J.1 peterg@ion.ucl.ac.uk |
| المصدر: |
Neuron. Mar2004, Vol. 41 Issue 5, p679. 2p. |
| مصطلحات موضوعية: |
*MIGRAINE, *CEREBROVASCULAR disease, *GENETIC mutation, *PHENOTYPES |
| مستخلص: |
Migraine aura is a sometimes disabling disorder of the brain that involves significant neurological symptoms in about 30% of patients. In this issue of Neuron, van den Maagdenberg et al. characterize a mouse with a knockin mutation known to cause familial hemiplegic migraine and provide evidence that a lowered threshold to the triggering of CSD may account for the devastating phenotype of familial hemiplegic migraine. [Copyright &y& Elsevier] |
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