المؤلفون: Remmerie, Anneleen, Martens, Liesbet, Scott, Charlotte

المصدر: FRONTIERS IN ENDOCRINOLOGY ; ISSN: 1664-2392

مصطلحات موضوعية: Biology and Life Sciences, Medicine and Health Sciences, NONALCOHOLIC STEATOHEPATITIS, LOCAL PROLIFERATION, HEPATIC RECRUITMENT, ADIPOCYTE DEATH, SPI-C, CELLS, INFLAMMATION, DEPLETION, NICHE, POLARIZATION, macrophages, adipose tissue, non-alcoholic fatty liver disease (NAFLD), single-cell, heterogeneity, liver, NASH (non-alcoholic steatohepatitis)

وصف الملف: text/plain

العلاقة: https://biblio.ugent.be/publication/8672783Test; http://hdl.handle.net/1854/LU-8672783Test; http://dx.doi.org/10.3389/fendo.2020.00259Test; https://biblio.ugent.be/publication/8672783/file/8672784Test

الإتاحة: https://doi.org/10.3389/fendo.2020.00259Test
https://biblio.ugent.be/publication/8672783Test
http://hdl.handle.net/1854/LU-8672783Test
https://biblio.ugent.be/publication/8672783/file/8672784Test

المؤلفون: Hans-Peter Hammes, Elena Heidenreich, Peter P. Nawroth, Martina U. Muckenthaler, Sandro Altamura, Thomas Fleming, Andrea Schlotterer, Katja Müdder, Ruiyue Qiu

المصدر: Molecular Metabolism, Vol 51, Iss, Pp 101235-(2021)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, DR, diabetic retinopathy, Hepcidin, medicine.disease_cause, Mice, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, MetS, Metabolic Syndrome, Internal medicine, biology, Fpn, Ferroportin, Fatty liver, Liver, DIOS, dysmetabolic iron overload syndrome, CRP, C-reactive protein, Receptors, Leptin, HH, hereditary hemochromatosis, Original Article, IRP, Iron Regulatory Protein, medicine.medical_specialty, Iron Overload, Iron, 030209 endocrinology & metabolism, Mice, Transgenic, IR, Insulin Resistance, SEM, standard error of the mean, 03 medical and health sciences, Insulin resistance, ROS, reactive oxygen species, NASH, Non Alcoholic Steatohepatitis, NAFLD, medicine, Animals, Humans, Molecular Biology, business.industry, NTBI, Non Transferrin Bound Iron, Cell Biology, medicine.disease, RC31-1245, IRS1, Db/db Mouse, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, NAFLD, Non Alcoholic Fatty Liver Disease, Lipid Peroxidation, Steatosis, Metabolic syndrome, business, Oxidative stress, IRE, Iron Responsive Element, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746ad7abfa625d87337f2502f8e59462Test
http://www.sciencedirect.com/science/article/pii/S2212877821000806Test

المؤلفون: F. Tuccillo, Joseph L. Evans, Antonella Borrelli, Franco M. Buonaguro, Ira D. Goldfine, P. Bonelli, Aldo Mancini

المصدر: Redox Biology, Vol 15, Iss C, Pp 467-479 (2018)
Redox Biology

مصطلحات موضوعية: Cirrhosis, HCC, Hepatocellular carcinoma, MnSOD, Manganese superoxide dismutase, Review Article, ecSOD, Extracellular Cu/ZnSOD, Biochemistry, Antioxidants, GIT, Gastrointestinal tract, 0302 clinical medicine, Fibrosis, MS, Metabolic syndrome, GLP-1, Glucagon-like peptide-1, LPS, Lipopolysaccharide, lcsh:QH301-705.5, Interventions, DASH, Drug-associated steatohepatitis, SSAO, Semicarbazide-sensitive amine oxidase, NKT, Natural killer T, Liver Neoplasms, NAFLD, Non-alcoholic fatty liver disease, PAMPs, Pathogen-associated molecular patterns (PAMPs), LPL, Lipoprotein lipase, PNPLA3, Patatin-like phospholipase 3, 030211 gastroenterology & hepatology, SCD1, Stearoyl-coenzyme A desaturase 1, AST, Aspartate aminotransferase, PGC-1α, Coactivator peroxisome proliferator-activated receptor-γ-1α, INT-747, Obeticholic acid (OCA), lcsh:Medicine (General), NADH, Nicotinamide adenine dinucleotide, LPB, Lipopolysaccharide-binding protein, Carcinoma, Hepatocellular, FIAF, Fasting-induced adipose factor, CS + WR, Cold storage and warm reperfusion, GF, Germ-free, FADH, Flavin adenine dinucleotide, NO, Nitric oxide, digestive system, CCR2/CCR5, C-C chemokine receptor types 2 and 5, 03 medical and health sciences, Manganese superoxide dismutase, Humans, CD14, Cluster of differentiation 14, NASH, Non-alcoholic steatohepatitis, Probiotics, nutritional and metabolic diseases, medicine.disease, VLX103, Venlafaxine-103, digestive system diseases, PIVENS, Pioglitazone versus Vitamin E versus Placebo, 030104 developmental biology, chemistry, PASH, PNPLA3-associated steatohepatitis, FXR, Farnesoid X receptor, CASH, Chemotherapy-associated steatohepatitis, LOXL, Lysyl oxidase and lysyl oxidase-like, Steatohepatitis, Reactive Oxygen Species, Mkt, Market, ROS, Reactive oxygen species, TZDs, Thiazolidinediones, 0301 basic medicine, ETC, Respiratory electron transport chain, Clinical Biochemistry, VAP-1, Vascular adhesion protein-1, PXS-4728A, SSAO/VAP-1 inhibitor BI 1467335, HVPG, Hepatic venous pressure gradient, •OH, Hydroxyl free radicals, HPC, Primary hepatic carcinoma, Chronic liver disease, SOD, Superoxide dismutase, FGF21, Fibroblast growth factor 21, aa, Amino acid, chemistry.chemical_compound, BASH, Both alcoholic and non-alcoholic liver disease, Non-alcoholic Fatty Liver Disease, H2, Molecular hydrogen, lcsh:R5-920, NAS, NAFLD activity score, medicine.diagnostic_test, NN2211, Liraglutide, O2, Molecular oxygen, Fatty liver, Elafibranor, Obeticholic acid, Drugs, ER, Estrogen receptor, IL-10, Interleukin-10, Liver, Liver biopsy, JNK, c-Jun N-terminal kinase, ASK1, Apoptosis signal- regulating kinase 1, Cu/ZnSOD, Copper/zinc superoxide dismutase, RG-125 AZD4076, N-acetylgalactosamine (GalNAc)-conjugated anti-miR-103/107 oligonucleotide, TLR, Toll-like receptor, H. pilory, Helicobacter pylori, HSCs, Hepatic stellate cells, PPAR, Peroxisome proliferator-activated receptor, medicine, ATP, Adenosine 5c-triphosphate, IL-6, Interleukin-6, MDA, Malondialdehyde, γgt, Gamma-glutamyl transferase, business.industry, Organic Chemistry, ALT, Alanine aminotransferase, TNF, Tumor necrosis factor, NF-κB, Nuclear factor kappa, O2·–, Superoxide anion, FGF19, Fibroblast growth factor 19, Gastrointestinal Microbiome, DPP-4 inhibitor, Dipeptidyl peptidase 4 inhibitor, FDA, Food and drug administration, Oxidative Stress, CVC, Cenicriviroc, lcsh:Biology (General), FFA, Free fatty acids, Cancer research, NAP, H. pylori-induced neutrophil-activating protein, Saroglitazar-ZYH1, [(S)-α-ethoxy-4-{2-[2-methyl-5-(4-methylthio) phenyl)]-1H-pyrrol-1-yl]-ethoxy})-benzenepropanoic acid magnesium salt], business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2419fc2467afc0fef89a4f91dd16f4cTest
http://www.sciencedirect.com/science/article/pii/S2213231717309291Test

المؤلفون: Giuseppe Poli, Maria Blonda, Giorgia di Bello, Luigi Iuliano, Gaetano Serviddio, Gianluigi Vendemiale, Carlo Avolio, Giuseppina Iannelli, Antonio Facciorusso, Rosanna Tamborra, Francesco Bellanti, Rosanna Villani

المصدر: Redox Biology, Vol 15, Iss C, Pp 86-96 (2018)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, MMP, mitochondrial membrane potential, 5α, 6α-epoxy, 5α,6α-epoxycholesterol, Clinical Biochemistry, HF+HCh, high-fat+high-cholesterol, Respiratory chain, Apoptosis, Mitochondria, Liver, Mitochondrion, medicine.disease_cause, Biochemistry, SDM, standard deviation of the mean, cholesterol excess, fatty acids, mitochondria, non-alcoholic fatty liver disease, oxysterols, Nonalcoholic fatty liver disease, lcsh:QH301-705.5, ANOVA, analysis of variance, TNF, tumor necrosis factor, lcsh:R5-920, Chemistry, UCP2, uncoupling protein 2, Oxysterols, Cholesterol excess, Mitochondria, Mitochondrial respiratory chain, Lipotoxicity, Liver, CTRL, control, Disease Progression, lipids (amino acids, peptides, and proteins), FFAs, free fatty acids, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, NASH, non-alcoholic steatohepatitis, Diet, High-Fat, 03 medical and health sciences, PA, palmitic acid, Δψ, mitochondrial membrane potential, HF, high-fat, Internal medicine, medicine, NAFL, non-alcoholic fatty liver, Humans, 5β, 6β-epoxy, 5β,6β-epoxycholesterol, Fatty acids, PGC1α, peroxisome proliferator-activated receptor-γ coactivator 1 α, TFAM, mitochondrial transcription factor A, NRF1, nuclear respiratory factor 1, Organic Chemistry, 6-oxo, 6-oxo-cholestan-3β,5α-diol, OA, oleic acid, CT, threshold cycle, medicine.disease, Lipid Metabolism, mtDNA, mitochondrial DNA, Oxidative Stress, 030104 developmental biology, Endocrinology, triol, 5α-cholestane-3β,5,6β-triol, Mitochondrial biogenesis, BN-PAGE, Blue Native bidimensional polyacrylamide gel electrophoresis, lcsh:Biology (General), Hepatocytes, 7β-OHC, 7β-hydroxycholesterol, Steatohepatitis, Reactive Oxygen Species, Oxidative stress, 7KC, 7-ketocholesterol, CYPs, cytochromes P450, Non-alcoholic fatty liver disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13897abda95ce40fb1e631f0e1a131eTest
http://www.sciencedirect.com/science/article/pii/S2213231717307425Test

المؤلفون: Miguel López, Rubén Nogueiras, Xabier Buqué, Maria J. Gonzalez-Rellan, Daniel Beiroa, Patricia Aspichueta, Uxia Fernandez, Begoña Porteiro, Rosalía Gallego, Carlos Dieguez, Guadalupe Sabio, Marcos F. Fondevila, Johan Fernø, Ana Senra, Alfonso Mora

المساهمون: Ministerio de Economía y Competitividad (España), Xunta de Galicia (España), Heise Vest RHF, Comunidad de Madrid (España), Basque Government (España), Fundación AstraZeneca, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Unión Europea. Comisión Europea, Centro de Investigación Biomedica en Red - CIBER

المصدر: Molecular Metabolism, Vol 8, Iss, Pp 132-143 (2018)
Molecular Metabolism
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: 0301 basic medicine, pIRE, Inositol-requiring enzyme 1 α, pJNK, phospho c-Jun N-terminal kinase, ACC, acetyl-CoA carboxylase, AST, aspartate aminotransferase, XBP1s, X-box binding protein 1, Abcd1, ATP binding cassette subfamily D member 1, Pharmacology, ER stress, endoplasmic reticulum stress, NFκβ, nuclear factor kappa b, FA, free fatty acid, Mice, Liver disease, UPR, unfolded protein response, 0302 clinical medicine, HFD, high fat diet, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, DG, diacylglycerol, Topoisomerase II Inhibitors, IL6, initerleukin 6, Beta oxidation, Acadm, acyl-CoA deshydrogenase, medium chain, GFP, green fluorescent protein, IL10, interleukin 10, Acox, acyl-CoA oxidase 1, TG, triglyceride, Ad, adenovirus, Hep G2 Cells, Acadl, acyl-CoA deshydrogenase, long-chain, i.p., intraperitoneal, FAS, fatty acid synthase, 3. Good health, Liver, Pparα, peroxisome proliferator activated receptor alpha, JNK, c-Jun N-terminal kinase, Lipogenesis, DOX, Doxorubicin, DN, dominant negative, Original Article, ApoB, apolipoprotein b, Quer, quercetin, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, ASM, acid-soluble metabolites, NASH, non-alcoholic steatohepatitis, TNFα, tumor necrosis factor alpha, GAPDH, glyceraldehyde-3-phosphate deshydrogenase, AUC, area under curve, Diet, High-Fat, Cell Line, SPF, specific pathogen free room, 03 medical and health sciences, GTT, glucose test tolerance, ALT, alanine aminotransferase, AAV8, adeno-associated virus serotype 8, medicine, Animals, Humans, Obesity, EC, sterified cholesterol, lcsh:RC31-1245, Molecular Biology, MCD, methionine-choline deficient diet, CHOP, C/EBP-homologous protein, Inflammation, business.industry, OA, oleic acid, Lipid metabolism, DIO, diet-induced obesity, Cell Biology, Lipid Metabolism, medicine.disease, CDHFD, choline-deficient high fat diet, Mice, Inbred C57BL, 030104 developmental biology, Doxorubicin, pACC, phospho acetyl-CoA carboxylase, Hepatic stellate cell, BSA, bovine serum albumin, Tumor Suppressor Protein p53, Steatohepatitis, Steatosis, business, Fatp2, solute carrier family 27 (fatty acid transporter) member 2, IL1β, interleukin 1beta, 030217 neurology & neurosurgery, ITT, insulin test tolerance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7642e1971aebb46c881386960e7affTest
http://www.sciencedirect.com/science/article/pii/S2212877817310116Test

المؤلفون: Adam J. Rauckhorst, Xiaorong Fu, Katherine N. Gibson-Corley, Alvin D. Pewa, Ryan D. Sheldon, Eric B. Taylor, James E. Cox, Charlotte R. Feddersen, Shawn C. Burgess, Adam J. Dupuy, Lawrence R. Gray

المصدر: Molecular Metabolism, Vol 6, Iss 11, Pp 1468-1479 (2017)
Molecular Metabolism

مصطلحات موضوعية: Blood Glucose, 0301 basic medicine, Mitochondria, Liver, Mitochondrion, Mitochondrial Membrane Transport Proteins, Mice, 0302 clinical medicine, HFD, high fat diet, Fibrosis, immune system diseases, Pyruvic Acid, digestive, oral, and skin physiology, Diabetes, Mitochondria, HOMA-IR, homeostatic model assessment of insulin resistance, medicine.anatomical_structure, Liver, Mitochondrial matrix, 030220 oncology & carcinogenesis, Hepatocyte, Original Article, MPC, mitochondrial pyruvate carrier, TCA, tricarboxylic acid cycle, Monocarboxylic Acid Transporters, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, lcsh:Internal medicine, NASH, non-alcoholic steatohepatitis, Anion Transport Proteins, Citric Acid Cycle, T2D, type 2 diabetes, Biology, Diet, High-Fat, Mitochondrial pyruvate carrier (MPC), 03 medical and health sciences, Internal medicine, medicine, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, ITT, insulin tolerance test, Inflammation, NCD, normal chow diet, Gluconeogenesis, Membrane Transport Proteins, nutritional and metabolic diseases, Cell Biology, Metabolism, medicine.disease, Citric acid cycle, Disease Models, Animal, Cytosol, Glucose, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Hyperglycemia, Hepatocytes, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80260421dd9726225c6f9a3cac3cf9faTest
http://www.sciencedirect.com/science/article/pii/S2212877817306828Test

المؤلفون: Guangyuan Zhang, Mitsuru Shimamura, Hitoshi Torii, Hideki Kizawa, Eri Nagao

المصدر: Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 186-191 (2017)
Biochemistry and Biophysics Reports

مصطلحات موضوعية: 0301 basic medicine, OAT, organic anion-transporting, medicine.medical_treatment, Biophysics, 02 engineering and technology, Biology, Biochemistry, Dex, Dexamethasone, lcsh:Biochemistry, 03 medical and health sciences, Liver disease, 8CPT-cAMP, 8-(4-Chlorophenylthio)adenosine 3′,5′-cyclic monophosphate, ECM, Extracellular matrix, MRP2, multidrug resistance-associated protein 2, medicine, lcsh:QD415-436, Protein kinase A signaling, lcsh:QH301-705.5, NASH, Non-alcoholic steatohepatitis, Bile duct, Bio-printing, Drug discovery, Insulin, HE, hematoxylin and eosin, Lipid metabolism, TUNEL, TdT-mediated dUTP nick end labeling, NAFLD, Non-alcoholic fatty liver disease, 021001 nanoscience & nanotechnology, medicine.disease, MT, Masson's trichrome, 030104 developmental biology, medicine.anatomical_structure, Metabolism, Drug development, Liver, lcsh:Biology (General), Toxicity, Scaffold-free, Liver function, 0210 nano-technology, Research Article, 3D

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c88df6cecf9c5b28a9b3ee07531addcTest
http://www.sciencedirect.com/science/article/pii/S2405580817300596Test

المؤلفون: Bricambert, Julien, Alves-Guerra, Marie-Clotilde, Esteves, Pauline, Prip-Buus, Carina, Bertrand-Michel, Justine, Guillou, Hervé, Chang, Christopher J., Vander Wal, Mark N., Canonne-Hergaux, François, Mathurin, Philippe, Raverdy, Violeta, Pattou, François, Girard, Jean, Postic, Catherine, Dentin, Renaud

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Santé Digestive (IRSD ), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Claude Huriez [Lille], CHU Lille, Service de chirurgie générale et endocrinienne, CHU Lille-CHU Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Prip-Buus, Carina, UMR 1048-12MC, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Hôpital Claude Huriez, Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Hôpital Claude Huriez-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), MetaToul-MetaboHUB, Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), ToxAlim (ToxAlim), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), University of California [Berkeley], University of California, Centre de Physiopathologie Toulouse Purpan (CPTP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Génomique Intégrative et Modélisation des Maladies Métaboliques (EGID), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Plateforme MetaToul, MetaboHUB, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS), Recherche translationnelle sur le diabète (RTD), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut Européen de Génomique du Diabète - EGID, Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Nature Communications
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩
Nature communications, vol 9, iss 1
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Frontiers in Genetics
Nature Communications 1 (9), . (2018)
Bricambert, J; Alves-Guerra, M-C; Esteves, P; Prip-Buus, C; Bertrand-Michel, J; Guillou, H; et al.(2018). The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. NATURE COMMUNICATIONS, 9. doi: 10.1038/s41467-018-04361-y. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1350n6p7Test

مصطلحات موضوعية: Male, [SDV]Life Sciences [q-bio], epigenetics (MeSH), Inbred C57BL, NAFLD (non-alcoholic fatty liver disease), Histones, Pentose Phosphate Pathway, Mice, Non-alcoholic Fatty Liver Disease, 2.1 Biological and endogenous factors, histone modification, Phf2, Aetiology, lcsh:Science, Promoter Regions, Genetic, Cells, Cultured, Cancer, Mice, Knockout, Histone Demethylases, Cultured, General Commentary, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Liver Disease, Nuclear Proteins, Glutathione, [SDV] Life Sciences [q-bio], Liver, Alimentation et Nutrition, NF-E2-Related Factor 2, Science, Cells, Knockout, Chronic Liver Disease and Cirrhosis, Methylation, Article, Promoter Regions, Genetic, Genetics, Food and Nutrition, Animals, Humans, NASH (non-alcoholic steatohepatitis), Obesity, Metabolic and endocrine, Nutrition, Homeodomain Proteins, Prevention, Demethylation, Mice, Inbred C57BL, Enzyme Activation, Oxidative Stress, Glucose, lcsh:Q, Digestive Diseases, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4bd1d2c0617160f15d8e41c9b32d7b80Test
https://hal.science/hal-02122655Test

المؤلفون: Lionel Carneiro, François R Jornayvaz, Christine Sempoux, Corinne Leloup, Jean-Christophe Stehle, Mohamed Asrih, Luc Pellerin, Cendrine Repond

المساهمون: Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Service d'Endocrinologie, Diabétologie et Métabolisme, Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Department of Physiology, Université de Lausanne (UNIL), Université Catholique de Louvain (UCL), Département de Physiologie, Pellerin, Luc, Centre National de la Recherche Scientifique (CNRS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB), Université Catholique de Louvain = Catholic University of Louvain (UCL), the 'Societe francophone du Diabete', the program IdEx Bordeaux ANR-10-IDEX-03-02, the Leenaards Foundation and the Raymond Berger Foundation, Lausanne., Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), Centre Hospitalier Universitaire Vaudois [Lausanne] ( CHUV ), University of Lausanne, Université Catholique de Louvain ( UCL ), Université de Lausanne ( UNIL )

المصدر: Molecular metabolism, vol. 6, no. 12, pp. 1625-1633
Molecular Metabolism, Vol. 6, No 12 (2017) pp. 1625-1633
Molecular Metabolism, Vol 6, Iss 12, Pp 1625-1633 (2017)
Molecular metabolism
Molecular metabolism, Elsevier, 2017, 6 (12), pp.1625-1633. ⟨10.1016/j.molmet.2017.10.005⟩
Molecular Metabolism 12 (6), 1625-1633. (2017)
Molecular metabolism, Elsevier, 2017, 6 (12), pp.1625-1633. 〈10.1016/j.molmet.2017.10.005〉
Molecular Metabolism

مصطلحات موضوعية: Male, 0301 basic medicine, AMPK, a.u.c, Area Under the Curve, Hepatic steatosis, Haploinsufficiency, FA, Fatty Acids, Mice, 0302 clinical medicine, AMP-Activated Protein Kinase Kinases, NAFLD, Non-Alcoholic Fatty Liver Disease, S6K, Ribosomal protein S6 kinase, ddc:616, Symporters, Diabetes, Fatty liver, foie, Rd, Glucose disappearance rate, HFD, High Fat Diet, obésité, Liver, Endocrinologie et métabolisme, Sterol Regulatory Element Binding Protein 1, LDHB, Lactate DeHydrogenase isoform B, diabète, Monocarboxylic Acid Transporters, PC, Pyruvate Carboxylase, medicine.medical_specialty, lcsh:Internal medicine, NASH, Non-Alcoholic SteatoHepatitis, kinase, SREBP1, Sterol Regulatory Element Binding Protein 1, 030209 endocrinology & metabolism, Biology, Brief Communication, maladie, 03 medical and health sciences, Animals, Fatty Liver/genetics, Fatty Liver/metabolism, Lactic Acid/metabolism, Lipid Metabolism, Liver/metabolism, Monocarboxylic Acid Transporters/genetics, Monocarboxylic Acid Transporters/metabolism, Protein Kinases/metabolism, Sterol Regulatory Element Binding Protein 1/metabolism, Symporters/genetics, Symporters/metabolism, Lactate, NAFLD, Obesity, stéatose hépatique, Downregulation and upregulation, SD, Standard Diet, [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology, Internal medicine, medicine, TAG, TriAcylGlycerides, Lactic Acid, lcsh:RC31-1245, résistance à l'insuline, Molecular Biology, HGP, Hepatic Glucose Production, liver, nafld, diabetes, lactate, insulin-resistance, nonalcoholic steatohepatitis, disease, obesity, ER Stress, Endoplasmic Reticulum stress, Endocrinology and metabolism, GIR, Glucose Infusion Rate, Lipid metabolism, Cell Biology, Metabolism, medicine.disease, Sterol regulatory element-binding protein, Fatty Liver, AMPK, AMP-activated protein kinase, 030104 developmental biology, Endocrinology, MCT1, Monocarboxylate Transporter isoform 1, mTOR, mammalian Target Of Rapamycin, Steatosis, ACC, Acetyl-CoA Carboxylase, Protein Kinases, Drug metabolism, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, ROS, Reactive Oxygen Species, LDHA, Lactate DeHydrogenase isoform A

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845a9eee5fd517d81211c0a9c97bf132Test
https://serval.unil.ch/notice/serval:BIB_1E26E53BF1FETest

المؤلفون: Kasper W. ter Horst, Pim W. Gilijamse, Ahmet Demirkiran, Max Nieuwdorp, Joanne Verheij, Mariëtte T. Ackermans, Mireille J. Serlie, Bart A. van Wagensveld, Johannes A. Romijn, Mark A. Herman, Eleftheria Maratos-Flier

المساهمون: Graduate School, Other Research, Laboratory for Endocrinology, Pathology, General Internal Medicine, Amsterdam Cardiovascular Sciences, Amsterdam Gastroenterology Endocrinology Metabolism, Vascular Medicine, Endocrinology, ACS - Diabetes & metabolism, Internal medicine

المصدر: Molecular metabolism, 6(11), 1493-1502. Elsevier GmbH
Molecular Metabolism, 6(11), 1493-1502. Elsevier GmbH
ter Horst, K W, Gilijamse, P W, Demirkiran, A, van Wagensveld, B A, Ackermans, M T, Verheij, J, Romijn, J A, Nieuwdorp, M, Maratos-Flier, E, Herman, M A & Serlie, M J 2017, ' The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans ', Molecular Metabolism, vol. 6, no. 11, pp. 1493-1502 . https://doi.org/10.1016/j.molmet.2017.08.014Test
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1493-1502 (2017)

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, FGF21, medicine.medical_treatment, Bariatric Surgery, FGF21, fibroblast growth factor 21, AUC, area under the curve, EGP, endogenous glucose production, chemistry.chemical_compound, 0302 clinical medicine, Weight loss, Insulin, Middle Aged, Fructose Intolerance, Obesity, Morbid, Liver, Female, Original Article, medicine.symptom, Rd, rate of disappearance, Adult, lcsh:Internal medicine, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, ChREBP, carbohydrate response element-binding protein, GLP1, glucagon-like peptide 1, NASH, non-alcoholic steatohepatitis, Gastric Bypass, Translational study, 030209 endocrinology & metabolism, Fructose, Biology, 03 medical and health sciences, Insulin resistance, Internal medicine, Weight Loss, FFA, free fatty acid, medicine, Humans, Obesity, lcsh:RC31-1245, Carbohydrate-responsive element-binding protein, Molecular Biology, IQR, interquartile range, Ra, rate of appearance, Cell Biology, medicine.disease, Fatty Liver, Fibroblast Growth Factors, Glucose, 030104 developmental biology, Endocrinology, chemistry, Hyperinsulinemic-euglycemic clamp, Energy Metabolism, SD, standard deviation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2e659739c9955525826cd9525c9c29Test
https://pure.amc.nl/en/publications/the-fgf21-response-to-fructose-predicts-metabolic-health-and-persists-after-bariatric-surgery-in-obese-humansTest(1b1e6aa9-0f4a-4f37-b984-a10e3cf4e1ba).html