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المؤلفون: Hong Soon Kang, Anton M. Jetten, Kevin Gerrish, Amir Aghajanian, Ju Youn Beak, Brian C. Jensen, Seok Jae Hong, Wei Huang, Rishi Deshmukh, Nishi Kadakia
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: HIF-1α, hypoxia-inducible factor-1α, Caveolin 3, PINK1, PTEN-induced putative kinase 1, LC3B-II, microtubule-associated protein light chain beta 3-II, Mitochondrion, Biochemistry, CMKO, cardiomyocyte-specific RORα KO, JC-1, 5, 5′, 6, 6′-tetrachloro-1, 1′, 3, 3′-tetraethylbenzimidazolylcarbocyanine iodide, Mitochondria, Heart, Mice, Mitophagy, OCR, oxygen consumption rate, Myocytes, Cardiac, Cav-3, caveolin-3, mt-Keima, mitochondrial-targeted Keima, shCtrl, scrambled shRNA, Cardioprotection, Gene knockdown, LDH, lactate dehydrogenase, Bnip3, BCL2 interacting protein 3, HRP, horseradish peroxidase, Nuclear Receptor Subfamily 1, Group F, Member 1, shRORα, shRNA against RORα, Cell biology, ChIP, chromatin immunoprecipitation, BFA1, bafilomycin A1, SDH, succinate dehydrogenase, NRVMs, neonatal rat ventricular myocytes, qRT-PCR, quantitative RT-PCR, Research Article, caveolin-3, mPTP, mitochondrial permeability transition pore, cardiomyocyte mitochondrial physiology, Biology, ROS, reactive oxygen species, Downregulation and upregulation, Animals, TEM, transmission electron microscopy, Molecular Biology, ROR, retinoic acid–related orphan nuclear receptor, Ang II, angiotensin II, hypoxia, Autophagy, Cell Biology, RAR-related orphan receptor alpha (ROR-alpha), Nuclear receptor, Hsp60, heat shock protein 60, PFA, paraformaldehyde
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cc243bde3123b1ebf3e9dc15c170f2Test
http://europepmc.org/articles/PMC8626585Test -
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المؤلفون: Richard L. Gallo, Tatsuya Dokoshi, Alan M. O’Neill, Elizabeth Wei Chia Luo, Nikhil Nitin Kulkarni, Gerard C. L. Wong
المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, medicine.medical_treatment, Inbred C57BL, Biochemistry, Medical and Health Sciences, Cathelicidin, Mice, Double-Stranded, antimicrobial peptides, SR, scavenger receptor, Receptors, cathelicidin, Innate, Receptor, GAS, group A Streptococcus, Receptors, Scavenger, Alanine, LDH, lactate dehydrogenase, Chemistry, LL-37, 37-amino acid peptide, UCSD, University of California, San Diego, SAXS, small-angle X-ray scattering, interferon, Alanine scanning, Biological Sciences, Cell biology, IL-6, interleukin 6, Infectious Diseases, LL-34, 34-amino acid peptide, Interferon Type I, qRT-PCR, quantitative RT-PCR, Female, NHEK, normal human epidermal keratinocyte, Transcription, RIGI, retinoic acid–inducible gene I, Research Article, Protein Binding, Signal Transduction, Biochemistry & Molecular Biology, skin, HDMEC, human dermal microvascular endothelial cell, MIC, minimum inhibitory concentration, Antimicrobial peptides, I20P, proline at isoleucine position 20, IRF7, interferon regulatory factor 7, Biophysical Phenomena, Scavenger, MAVS, mitochondrial antiviral signaling, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, Genetic, Cathelicidins, GO, Gene Ontology, medicine, Genetics, Animals, Humans, Amino Acid Sequence, Molecular Biology, RNA, Double-Stranded, Inflammation, Innate immune system, 030102 biochemistry & molecular biology, Cell Membrane, Immunity, RNA, Cell Biology, cytokines, Immunity, Innate, Toll-Like Receptor 3, Mice, Inbred C57BL, 030104 developmental biology, Emerging Infectious Diseases, Gene Expression Regulation, Chemical Sciences, TBK1, TANK-binding kinase 1, Mutation, Nucleic acid, Antimicrobial Cationic Peptides
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7653124affc7f3c4f58a75aed7ae4eb7Test
http://europepmc.org/articles/PMC8214221Test -
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المؤلفون: Yoshitake Cho, Anne N. Murphy, Alex Liang, Shamim Khosrowjerdi, Oliver R. Zhang, Robert S. Ross, Aleksander Andreyev, Kayla Lam, Ruixia Li, Shizuko Tachibana, Yoh Arita
المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1مصطلحات موضوعية: 0301 basic medicine, mitochondrial biogenesis, ATP5B, Messenger, NCM, neonatal cardiomyocytes, Muscle Proteins, cardiomyocytes, Mitochondrion, PGC-1, PPARgamma coactivator 1, SDHb, succinate dehydrogenase complex iron–sulfur subunit B, Inbred C57BL, Cardiovascular, Biochemistry, Medical and Health Sciences, OxPhos, oxidative phosphorylation, Oxidative Phosphorylation, Mice, Cox, cytochrome c oxidase, oxidative metabolism, Receptors, Myocyte, Protein Isoforms, 2.1 Biological and endogenous factors, OCR, oxygen consumption rate, Perm1, peroxisome proliferator-activated receptor coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator, muscle 1, Aetiology, Organelle Biogenesis, Heart development, LDH, lactate dehydrogenase, Intracellular Signaling Peptides and Proteins, Heart, Biological Sciences, Cell Hypoxia, Cell biology, Mitochondria, Mitochondrial, Heart Disease, 5.1 Pharmaceuticals, medicine.symptom, Development of treatments and therapeutic interventions, Mito, mitochondrial, Cardiac, Transcription, Oxidation-Reduction, Perm1, NDUFS3, NADH dehydrogenase [ubiquinone] iron–sulfur protein 3, Research Article, Programmed cell death, Biochemistry & Molecular Biology, Heart Ventricles, Down-Regulation, ATP5b, ATP synthase F1 subunit beta, Biology, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, Promoter Regions, 03 medical and health sciences, H/R, hypoxia-reoxygenation, UQCRC2, ubiquinol-cytochrome C reductase core protein 2, Genetic, Coactivator, medicine, Genetics, COXIV, cytochrome c oxidase subunit IV, Animals, Humans, Molecular Biology, Heart Failure, Myocytes, 030102 biochemistry & molecular biology, Cell Biology, DNA, Hypoxia (medical), Estrogen, Oxygen, ERR, estrogen-related receptor, 030104 developmental biology, Mitochondrial biogenesis, SERCA, Sarco/endoplasmic reticulum Ca2+-ATPase, Protein Biosynthesis, Musculoskeletal, Chemical Sciences, RNA, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352ef9a79b8dfcd8924d67bb08dbe283Test
http://europepmc.org/articles/PMC8214196Test -
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المؤلفون: Yan Wang, Yalin Wu, Zuguo Liu, Jingmeng Chen, Chao Chen
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, STEAP3, six-transmembrane epithelial antigen of prostate 3, genetic structures, STGD1, autosomal recessive Stargardt disease, TFRC, transferrin receptor, ONL, outer nuclear layer, Mitochondrion, medicine.disease_cause, Biochemistry, Photoreceptor cell, Mice, DMT1, Divalent metal transporter 1, GSH, glutathione, Stargardt Disease, oxidative stress, iron metabolism, AMD, age-related macular degeneration, IREB2, Iron-responsive element binding protein 2, POS, photoreceptor outer segments, chemistry.chemical_classification, Deferoxamine mesylate, LDH, lactate dehydrogenase, Chemistry, TEM, transmission electron microscope, lipid peroxidation, LED, light emitting diode, Cell biology, medicine.anatomical_structure, cell death, Retinaldehyde, Photoreceptor Cells, Vertebrate, Research Article, Programmed cell death, macular degeneration, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Animals, Ferroptosis, Molecular Biology, Reactive oxygen species, Retina, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, all-trans-retinal, photoreceptor, eye diseases, TF, transferrin, Mice, Inbred C57BL, 030104 developmental biology, CP, ceruloplasmin, atRAL, all-trans-retinal, H&E, hematoxylin and eosin, sense organs, FPN, Ferroportin, Reactive Oxygen Species, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212aTest
https://pubmed.ncbi.nlm.nih.gov/33334878Test -
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المؤلفون: Mona A. Abraham, Mozhgan Rasti, Tony K.T. Lam, Paige V. Bauer
المصدر: The Journal of biological chemistry. 293(11)
مصطلحات موضوعية: 0301 basic medicine, Leptin, Male, medicine.medical_specialty, Glucose uptake, Lactate dehydrogenase A, Hypothalamus, Carbohydrate metabolism, Diet, High-Fat, Biochemistry, Gene Expression Regulation, Enzymologic, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Internal medicine, Lactate dehydrogenase, Diabetes mellitus, Glucose Intolerance, medicine, Glucose homeostasis, Animals, Homeostasis, education, Molecular Biology, education.field_of_study, L-Lactate Dehydrogenase, Chemistry, Cell Biology, Glucose Tolerance Test, medicine.disease, Rats, 030104 developmental biology, Endocrinology, Glucose, Metabolism, Insulin Resistance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a17b5e5c4b1fc36104e19cdac48998Test
https://pubmed.ncbi.nlm.nih.gov/29374061Test -
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المؤلفون: Xenia Schafer, Sergiy M. Nadtochiy, Paul S. Brookes, Joshua Munger, Keith Nehrke, James H. Miller, Dragony Fu
المصدر: The Journal of biological chemistry. 291(38)
مصطلحات موضوعية: 0301 basic medicine, Male, Mutant, Dehydrogenase, Biology, Biochemistry, Malate dehydrogenase, Glutarates, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Malate Dehydrogenase, Lactate dehydrogenase, medicine, Animals, Molecular Biology, 030304 developmental biology, Acidosis, chemistry.chemical_classification, 0303 health sciences, L-Lactate Dehydrogenase, Cell Biology, Metabolism, Hydrogen-Ion Concentration, Isoenzymes, Cytosol, Alcohol Oxidoreductases, 030104 developmental biology, Isocitrate dehydrogenase, Enzyme, chemistry, 030220 oncology & carcinogenesis, Hypoxia-Inducible Factor 1, medicine.symptom, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a369b15b0d271f7a50d09e61fc0124b8Test
https://pubmed.ncbi.nlm.nih.gov/27510037Test -
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المؤلفون: JuFang Wang, Barbara A. Miller, Santhanam Shanmughapriya, Xue-Qian Zhang, Salim Merali, Joseph Y. Cheung, Yoshinori Takahashi, Mustafa Barbour, Michael G. Bayerl, Kathleen Conrad, Kerry Keefer, Lei Bao, Tianyu Sun, Hong Gang Wang, Iwona Hirschler-Laszkiewicz, Jianliang Song, Nicholas E. Hoffman, Shu Jen Chen, Carlos A. Barrero, Thomas Abraham, Yuguang Shi, Yuka Imamura Kawasawa, Muniswamy Madesh
المصدر: The Journal of biological chemistry. 289(52)
مصطلحات موضوعية: Angiogenesis, Cell Survival, Lactate dehydrogenase A, Down-Regulation, Mice, Nude, TRPM Cation Channels, Mitochondrion, Biology, Biochemistry, Membrane Potentials, Superoxide dismutase, Neuroblastoma, Cell Line, Tumor, Mitophagy, Adrenal Glands, Autophagy, Basic Helix-Loop-Helix Transcription Factors, Animals, Humans, Protein Isoforms, Viability assay, education, Molecular Biology, Cell Proliferation, chemistry.chemical_classification, Membrane Potential, Mitochondrial, education.field_of_study, Reactive oxygen species, Antibiotics, Antineoplastic, Cell Biology, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, Tumor Burden, Gene Expression Regulation, Neoplastic, Protein Transport, Hypoxia-inducible factors, chemistry, Doxorubicin, biology.protein, Female, Neoplasm Transplantation, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f643a352608bd350ff12765549731febTest
https://pubmed.ncbi.nlm.nih.gov/25391657Test -
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المؤلفون: Ya Li Tan, Hsiao Wee Chng, Jian Lin Fu, Lei Zheng, Ru-Ping Dai, Yan Luo, Shuang Ru Goh, Fa-Xing Yu
المصدر: The Journal of biological chemistry. 283(40)
مصطلحات موضوعية: endocrine system, animal structures, Nitrosamines, Transcription, Genetic, Xenopus, Dehydrogenase, Cell Cycle Proteins, Biochemistry, Redox, S Phase, Histones, chemistry.chemical_compound, Transcription (biology), Lactate dehydrogenase, Animals, Humans, Promoter Regions, Genetic, Molecular Biology, Gene, Glyceraldehyde 3-phosphate dehydrogenase, biology, L-Lactate Dehydrogenase, Glyceraldehyde-3-Phosphate Dehydrogenases, Cell Biology, eye diseases, DNA-Binding Proteins, Histone, chemistry, Gene Expression Regulation, Multiprotein Complexes, biology.protein, NAD+ kinase, Oxidation-Reduction, HeLa Cells, Octamer Transcription Factor-1, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82ff938e49089bb104854079c19d76aTest
https://pubmed.ncbi.nlm.nih.gov/18682386Test -
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المؤلفون: Chiara Riganti, Manuela Polimeni, Amalia Bosia, Dario Ghigo, Costanzo Costamagna, Elena Gazzano
المصدر: The Journal of biological chemistry. 279(46)
مصطلحات موضوعية: animal diseases, Citric Acid Cycle, pentose phosphate pathway, Dehydrogenase, Pentose phosphate pathway, Glucosephosphate Dehydrogenase, medicine.disease_cause, Biochemistry, Cell Line, chemistry.chemical_compound, Mice, dehydroepiandrosterone, Onium Compounds, Lactate dehydrogenase, diphenyleneiodonium, diphenyliodonium, glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, reactive oxygen species, malonyldialdehyde, lactate dehydrogenase, glyceraldehyde 3-phosphate dehydrogenase, medicine, Animals, Enzyme Inhibitors, Molecular Biology, L-Lactate Dehydrogenase, Phosphogluconate Dehydrogenase, Biphenyl Compounds, Glyceraldehyde-3-Phosphate Dehydrogenases, Cell Biology, Glutathione, Molecular biology, Citric acid cycle, Oxidative Stress, Glucose, chemistry, Glutathione disulfide, NAD+ kinase, Neuroglia, Oxidation-Reduction, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fe07c5c147e53e0fb82421a17077e4Test
https://pubmed.ncbi.nlm.nih.gov/15358777Test -
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المؤلفون: Beatriz Velasco, Carmen Langa, Tilman Sanchez-Elsner, Luisa María Botella, Carmelo Bernabeu
المساهمون: Ministerio de Ciencia y Tecnología (España), Comunidad de Madrid, Sanchez-Elsner, Tilman, Botella,Luisa María, Bernabéu, Carmelo, Sanchez-Elsner, Tilman [0000-0003-1915-2410], Botella,Luisa María [0000-0002-6310-2245], Bernabéu, Carmelo [0000-0002-1563-6162]
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Umbilical Veins, Time Factors, Transcription, Genetic, Smooth-muscle cells, SMAD, Biochemistry, Binding-protein endoglin, Transforming Growth Factor beta, hemic and lymphatic diseases, Tumor Cells, Cultured, Hypoxia, Human solid tumors, Cells, Cultured, education.field_of_study, tgf-beta, biology, Endoglin, Nuclear Proteins, Cellular responses, U937 Cells, Flow Cytometry, Cell biology, Up-Regulation, DNA-Binding Proteins, Hereditary hemorrhagic telangiectasia, COS Cells, Hypoxia-Inducible Factor 1, Signal transduction, Plasmids, Protein Binding, Sp1 Transcription Factor, Lactate dehydrogenase A, Blotting, Western, Monoclonal-antibodies, Inducible factor-1, Vascular Cell Adhesion Molecule-1, Receptors, Cell Surface, Transfection, Antigens, CD, TGF beta signaling pathway, Coactivator, otorhinolaryngologic diseases, Animals, Humans, RNA, Messenger, education, Molecular Biology, Transcription factor, Binding Sites, Cell Biology, Transforming growth factor beta, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, Precipitin Tests, biology.protein, Endothelium, Vascular, Lactate-dehydrogenase-a, Vascular endothelial-cells, HeLa Cells, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11511436d551a2e2213d5f01ee41da2eTest
https://pubmed.ncbi.nlm.nih.gov/12228247Test