The New Biology of Diabetic Kidney Disease-Mechanisms and Therapeutic Implications
| العنوان: | The New Biology of Diabetic Kidney Disease-Mechanisms and Therapeutic Implications |
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| المؤلفون: | Hiddo J.L. Heerspink, Petter Bjornstad, Daniël H. van Raalte, Yuliya Lytvyn, David Z.I. Cherney |
| المصدر: | Lytvyn, Y, Bjornstad, P, van Raalte, D H, Heerspink, H L & Cherney, D Z I 2019, ' The New Biology of Diabetic Kidney Disease-Mechanisms and Therapeutic Implications ', Endocrine Reviews, vol. 41, no. 2, bnz010 . https://doi.org/10.1210/endrev/bnz010Test Endocr Rev |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Endothelin Receptor Antagonists, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Anti-Inflammatory Agents, Reviews, 030209 endocrinology & metabolism, Disease, 030204 cardiovascular system & hematology, Biology, Glucagon-Like Peptide-1 Receptor, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Diabetes mellitus, medicine, Humans, Hypoglycemic Agents, Diabetic Nephropathies, Myocardial infarction, Intensive care medicine, Sodium-Glucose Transporter 2 Inhibitors, Stroke, Mineralocorticoid Receptor Antagonists, Dipeptidyl-Peptidase IV Inhibitors, Diabetic kidney, medicine.disease, Obesity, Kidney disease |
| الوصف: | Diabetic kidney disease remains the most common cause of end-stage kidney disease in the world. Despite reductions in incidence rates of myocardial infarction and stroke in people with diabetes over the past 3 decades, the risk of diabetic kidney disease has remained unchanged, and may even be increasing in younger individuals afflicted with this disease. Accordingly, changes in public health policy have to be implemented to address the root causes of diabetic kidney disease, including the rise of obesity and diabetes, in addition to the use of safe and effective pharmacological agents to prevent cardiorenal complications in people with diabetes. The aim of this article is to review the mechanisms of pathogenesis and therapies that are either in clinical practice or that are emerging in clinical development programs for potential use to treat diabetic kidney disease. |
| اللغة: | English |
| تدمد: | 0163-769X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dacfd85a4d0ef3670be947c2f3fe3aTest http://www.scopus.com/inward/record.url?scp=85079470833&partnerID=8YFLogxKTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....35dacfd85a4d0ef3670be947c2f3fe3a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 0163769X |
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