التفاصيل البيبلوغرافية
| العنوان: |
The association of infrared imaging findings of the breast with prognosis in breast cancer patients: an observational cohort study. |
| المؤلفون: |
Li-An Wu, Wen-Hung Kuo, Chin-Yu Chen, Yuh-Show Tsai, Jane Wang, Wu, Li-An, Kuo, Wen-Hung, Chen, Chin-Yu, Tsai, Yuh-Show, Wang, Jane |
| المصدر: |
BMC Cancer; 7/27/2016, Vol. 16, p1-7, 7p, 6 Charts, 2 Graphs |
| مصطلحات موضوعية: |
BREAST cancer patients, BREAST cancer prognosis, BREAST cancer diagnosis, INFRARED imaging, CHI-squared test, BREAST tumors, CANCER relapse, CLINICAL trials, COMPARATIVE studies, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, MEDICAL thermography, PROGNOSIS, RESEARCH, TUMOR classification, THREE-dimensional imaging, EVALUATION research, PROPORTIONAL hazards models |
| مستخلص: |
Background: To evaluate whether infrared (IR) imaging findings are associated with prognosis in patients with invasive breast carcinomas.Methods: This study was approved by the institutional review board of the research ethics committee of our hospital, and all participants gave written informed consent. From March 2005 to June 2007, we enrolled 143 patients with invasive breast cancer that underwent preoperative IR imaging. We used five IR signs to interpret breast IR imaging. Cox proportional hazards model was used to evaluate the effect of IR signs on long-term mortality.Results: During a median follow-up of 2451 days (6.7 years), 31 patients died. Based on the Cox Proportional Hazards Model, IR1 sign (the temperature of cancer site minus that of the contralateral mirror imaging site) was positively associated with mortality in the univariate analysis (overall mortality hazard ratio [HR], 2.29; p = 0.03; disease-specific mortality HR, 2.57; p = 0.04) as well as the multivariate analysis after controlling for clinicopathological factors (overall mortality HR, 3.85; p = 0.01; disease-specific mortality HR, 3.91, p = 0.02). In patients with clinical stage I and II disease, IR1 was also positively associated with mortality (overall mortality HR, 3.76; p = 0.03; disease-specific mortality HR, 4.59; p = 0.03). Among patients with node-negative disease, IR1 and IR5 (asymmetrical thermographic pattern) were associated with mortality (p = 0.04 for both IR1 and IR5, chi-squared test).Conclusion: Breast IR findings are associated with mortality in patients with invasive breast carcinomas. The association remained in patients with node-negative disease.Trial Registration: NCT00166998 . [ABSTRACT FROM AUTHOR] |
|
Copyright of BMC Cancer is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder