دورية أكاديمية

Effect of photodynamic therapy adjunct to scaling and root planing in periodontitis patients: A randomized clinical trial.

التفاصيل البيبلوغرافية
العنوان: Effect of photodynamic therapy adjunct to scaling and root planing in periodontitis patients: A randomized clinical trial.
المؤلفون: Pulikkotil, SJ, Toh, CG, Mohandas, K, Leong, KVG, Pulikkotil, S J, Toh, C G
المصدر: Australian Dental Journal; Dec2016, Vol. 61 Issue 4, p440-445, 6p
مصطلحات موضوعية: ACTINOBACILLUS actinomycetemcomitans, SPLIT-mouth trials (Dentistry), PHOTODYNAMIC therapy, CLINICAL trials, PERIODONTAL disease, PHYSICAL therapy, CHRONIC diseases, COMBINED modality therapy, COMPARATIVE studies, DENTAL plaque, DENTAL scaling, GRAM-negative bacteria, GRAM-negative bacterial diseases, RESEARCH methodology, MEDICAL cooperation, PERIODONTICS, PERIODONTITIS, PHOTOCHEMOTHERAPY, POLYMERASE chain reaction, RESEARCH, STATISTICAL sampling, TOOTH root planing, EVALUATION research, RANDOMIZED controlled trials, TREATMENT effectiveness
مستخلص: Background: A randomized split-mouth controlled clinical trial was conducted to evaluate the efficacy of photodynamic therapy (PDT) in reducing Aggregatibacter actinomycetemcomitans (Aa) in periodontitis patients.Methods: Twenty patients with periodontitis were recruited for the trial. Following random allocation of either quadrants of the selected jaw to test or control treatment, conventional non-surgical periodontal therapy (NSPT) was performed. In addition, the test side received adjunct photodynamic therapy. Probing depth (PD), clinical attachment level, bleeding on probing (BoP) and plaque scores (PS%) were recorded at phase 0 (baseline), phase 1 (immediately after NSPT), phase 2 (7 days following NSPT), phase 3 (1 month following NSPT) and phase 4 (3 months following NSPT). Subgingival plaque samples for quantification of Aa by real-time polymerase chain reaction was performed at phases 0, 1, 2 and 4.Results: There was a significant clinical improvement at phases 3 and 4 compared with baseline while BoP reduced significantly only in the test group at phase 4. However, no difference in the quantification of Aa was detected between the groups.Conclusions: Within the limits of the study, PDT adjunct to scaling and root planing does not lead to quantitative reduction of Aa in periodontitis patients. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00450421
DOI:10.1111/adj.12409