Long-term follow up in type A insulin resistant syndrome treated by insulin-like growth factor I
| العنوان: | Long-term follow up in type A insulin resistant syndrome treated by insulin-like growth factor I |
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| المؤلفون: | A Kawakita, H Ishihama, M Nagai, Y Nishimura, H Shiraya, M Kokubo, M Kobayashi, T Imamura, K Muramatsu, Y Suzuki |
| المصدر: | Archives of Disease in Childhood. 71:144-146 |
| بيانات النشر: | BMJ, 1994. |
| سنة النشر: | 1994 |
| مصطلحات موضوعية: | Blood Glucose, medicine.medical_specialty, Erythrocytes, Side effect, medicine.medical_treatment, Lymphocyte Activation, Insulin-like growth factor, Internal medicine, Diabetes Mellitus, medicine, Humans, Insulin, Testosterone, Acanthosis Nigricans, Lymphocytes, Insulin-Like Growth Factor I, Child, biology, business.industry, Growth factor, Hyperandrogenism, Syndrome, Fibroblasts, medicine.disease, Polycystic ovary, Receptor, Insulin, Insulin receptor, Endocrinology, Pediatrics, Perinatology and Child Health, biology.protein, Female, Insulin Resistance, business, Follow-Up Studies, Polycystic Ovary Syndrome, Research Article |
| الوصف: | Insulin-like growth factor I (IGF-I) is a useful therapeutic agent in insulin resistant diabetes mellitus due to insulin receptor disease because of its hypoglycaemic effects through the IGF-I receptor. A girl with typical type A insulin resistant syndrome was treated with IGF-I for two years and the treatment was effective in ameliorating hyperglycaemia. Overproduction of testosterone in polycystic ovaries was aggravated with this treatment, however. Therefore, IGF-I treatment may be used for glycaemic control but with caution because of its possible side effect of aggravating hyperandrogenism in these patients. |
| تدمد: | 1468-2044 0003-9888 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ff87be9f79186166b5cf7b4668f154Test https://doi.org/10.1136/adc.71.2.144Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....13ff87be9f79186166b5cf7b4668f154 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14682044 00039888 |
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