المؤلفون: Peter J. Mullen, Gustavo Garcia, Arunima Purkayastha, Nedas Matulionis, Ernst W. Schmid, Milica Momcilovic, Chandani Sen, Justin Langerman, Arunachalam Ramaiah, David B. Shackelford, Robert Damoiseaux, Samuel W. French, Kathrin Plath, Brigitte N. Gomperts, Vaithilingaraja Arumugaswami, Heather R. Christofk

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/fb48f36f0ee14f8194aa51fcf0be0cc6Test

المؤلفون: Joseph Longo, Peter J. Mullen, Rosemary Yu, Jenna E. van Leeuwen, Mehdi Masoomian, Dixon T.S. Woon, Yuzhuo Wang, Eric X. Chen, Robert J. Hamilton, Joan M. Sweet, Theodorus H. van der Kwast, Neil E. Fleshner, Linda Z. Penn

المصدر: Molecular Metabolism, Vol 25, Iss , Pp 119-130 (2019)

مصطلحات موضوعية: Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2212877819300882Test; https://doaj.org/toc/2212-8778Test

الوصول الحر: https://doaj.org/article/f03d8eaff63e4e4990bc23cc62eb3734Test

المؤلفون: Sriraksha Bharadwaj Kashyap, Racheal Mulondo, Peter J. Mullen

المصدر: Cell metabolism. 34(9)

مصطلحات موضوعية: Epstein-Barr Virus Infections, Herpesvirus 4, Human, Methionine, Physiology, Humans, Cell Biology, Molecular Biology, Virus Latency

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf751375f4bf59a3174c75f30514b5ebTest
https://pubmed.ncbi.nlm.nih.gov/36070681Test

المؤلفون: Nedas Matulionis, Peter J. Mullen, Arunachalam Ramaiah, Chandani Sen, Samuel W. French, Vaithilingaraja Arumugaswami, Ernst W. Schmid, Robert Damoiseaux, Kathrin Plath, Milica Momcilovic, Brigitte N. Gomperts, David B. Shackelford, Arunima Purkayastha, Gustavo Garcia, Justin Langerman, Heather R. Christofk

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature communications, vol 12, iss 1

مصطلحات موضوعية: 0301 basic medicine, viruses, Glutamine, General Physics and Astronomy, mTORC1, Virus Replication, 0302 clinical medicine, Chlorocebus aethiops, 2.1 Biological and endogenous factors, Aetiology, skin and connective tissue diseases, Lung, Multidisciplinary, respiratory system, Pyruvate carboxylase, Cell biology, Infectious Diseases, Mechanisms of disease, 5.1 Pharmaceuticals, TOR signalling, Benzamides, Respiratory, Mucosal immunology, Development of treatments and therapeutic interventions, Infection, Science, Morpholines, Citric Acid Cycle, Biology, Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, Animals, Humans, Naphthyridines, Protein Kinase Inhibitors, Vero Cells, Pyruvate Carboxylase, SARS-CoV-2, HEK 293 cells, COVID-19, Pneumonia, General Chemistry, Metabolism, biochemical phenomena, metabolism, and nutrition, respiratory tract diseases, 030104 developmental biology, Glucose, HEK293 Cells, Pyrimidines, Viral replication, Cell culture, Viral infection, Vero cell, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac75753ea6cfdc1e6711e570eefe016eTest
https://pubmed.ncbi.nlm.nih.gov/33767183Test

المؤلفون: Peter J. Mullen, Rosemary Yu, Jenna E. van Leeuwen, Wail Ba-alawi, Joseph Longo, Linda Z. Penn, Benjamin Haibe-Kains

المصدر: Cancer Research. 78:1347-1357

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Statin, medicine.drug_class, Protein Prenylation, Farnesyl pyrophosphate, Mevalonic Acid, Apoptosis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Polyisoprenyl Phosphates, Prenylation, Neoplasms, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Humans, HRAS, Fluvastatin, Cell Proliferation, Zinc Finger E-box-Binding Homeobox 1, 3. Good health, 030104 developmental biology, Oncology, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer cell, ras Proteins, Cancer research, Protein prenylation, lipids (amino acids, peptides, and proteins), Ras superfamily, Sesquiterpenes, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172d0af6f57cd0142de641e82bd842fdTest
https://doi.org/10.1158/0008-5472.can-17-1231Test

المؤلفون: David B. Shackelford, Steven D. Mittelman, Ernst W. Schmid, Peter J. Mullen, Milica Momcilovic, Simon R.V. Knott, Abigail S. Krall, Apisadaporn Thambundit, Heather R. Christofk, Felicia Surjono, Costas A. Lyssiotis, Christopher J. Halbrook

المصدر: Cell metabolism, vol 33, iss 5

مصطلحات موضوعية: 0301 basic medicine, Physiology, cancer metabolism, mTORC1, Medical Biochemistry and Metabolomics, Mice, chemistry.chemical_compound, 0302 clinical medicine, Mice, Inbred NOD, Neoplasms, Asparagine, Cancer, Tumor, Nucleotides, Chemistry, asparagine, Metformin, Mitochondria, Survival Rate, Biochemistry, Intracellular, Asparaginase, Context (language use), Mechanistic Target of Rapamycin Complex 1, cancer treatment, Cell Line, Endocrinology & Metabolism, 03 medical and health sciences, Cell Line, Tumor, Respiration, Animals, Humans, Molecular Biology, Cell Proliferation, Aspartic Acid, Cell growth, ATF4, dietary restriction, Cell Biology, asparaginase, Activating Transcription Factor 4, Diet, 030104 developmental biology, Electron Transport Chain Complex Proteins, Inbred NOD, Biochemistry and Cell Biology, respiration, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ff698e1ed01342f983891c97c95357Test
https://doi.org/10.1016Test/j.cmet.2021.02.001

المؤلفون: Eric Chen, Mehdi Masoomian, Peter J. Mullen, Joan Sweet, Theodorus van der Kwast, Joseph Longo, Neil E. Fleshner, Rosemary Yu, Linda Z. Penn, Jenna E. van Leeuwen, Yuzhuo Wang, Robert J. Hamilton, Dixon T.S. Woon

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 25, Iss, Pp 119-130 (2019)

مصطلحات موضوعية: 0301 basic medicine, Male, Mevalonate pathway, Drug repurposing, Apoptosis, Mice, SCID, Prostate cancer, Mice, 0302 clinical medicine, Mice, Inbred NOD, Medicine, Dipyridamole, 3. Good health, Sterols, lipids (amino acids, peptides, and proteins), Original Article, medicine.drug, Sterol Regulatory Element Binding Protein 2, lcsh:Internal medicine, Programmed cell death, Statin, medicine.drug_class, Cell Survival, Mevalonic Acid, 030209 endocrinology & metabolism, Antineoplastic Agents, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, Animals, Viability assay, lcsh:RC31-1245, Fluvastatin, Molecular Biology, Tumor metabolism, business.industry, Drug Repositioning, Statins, Prostatic Neoplasms, Cell Biology, medicine.disease, Lipid Metabolism, Xenograft Model Antitumor Assays, Sterol regulatory element-binding protein, 030104 developmental biology, Cancer research, Hydroxymethylglutaryl CoA Reductases, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2157c71470c4e70e8e94eed012f71aTest
https://pubmed.ncbi.nlm.nih.gov/31023626Test

المؤلفون: Karl S. Lang, Janice T. Pong, Peter J. Mullen, Elke Ericson, Jason Moffat, Corey Nislow, Kevin R. Brown, Rosemary Yu, Traver Hart, Aleksandra A. Pandyra, Piyush Sharma, Marinella Gebbia, Manpreet Kalkat, Guri Giaever, Carolyn A. Goard, Linda Z. Penn

المصدر: Oncotarget

مصطلحات موضوعية: Hydroxymethylglutaryl-CoA Synthase, Indoles, Lung Neoplasms, Medizin, Mevalonic Acid, Antineoplastic Agents, Apoptosis, Breast Neoplasms, Mevalonic acid, Biology, Real-Time Polymerase Chain Reaction, statins, Small hairpin RNA, Fatty Acids, Monounsaturated, chemistry.chemical_compound, feedback inhibition, RNA interference, Cell Line, Tumor, Neoplasms, Farnesyltranstransferase, Humans, RNA, Small Interfering, Fluvastatin, Transcription factor, Cell Proliferation, Gene knockdown, mevalonate pathway, Geranyltranstransferase, Dimethylallyltranstransferase, Molecular biology, Gene Expression Regulation, Neoplastic, Oncology, chemistry, Cancer research, lipids (amino acids, peptides, and proteins), tumor metabolism, Female, Hydroxymethylglutaryl CoA Reductases, RNA Interference, GGPS1, Mevalonate pathway, SREBP2, Research Paper, Sterol Regulatory Element Binding Protein 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461f085c99e7d15a9c40fd98cab6e0ccTest
http://europepmc.org/articles/PMC4694962Test

المؤلفون: Peter J. Mullen, Ahmed Aman, Linda Z. Penn, Benjamin Haibe-Kains, Aaliya Tamachi, Wail Ba-alawi, Rima Al-awar, David W. Cescon, Cornelia Redel, Cheryl H. Arrowsmith, Yu-Jia Shiah, Dharmendra Dingar, Brian Raught, William B. Tu, Corey Lourenco, Paul C. Boutros

المصدر: Cancer cell. 34(4)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Carcinogenesis, Gene Expression, Biology, medicine.disease_cause, Malignant transformation, Epigenesis, Genetic, 03 medical and health sciences, Mice, Cell Line, Tumor, Histocompatibility Antigens, Histone methylation, medicine, Animals, Humans, Epigenetics, Promoter Regions, Genetic, Psychological repression, Chromatin binding, Cell Biology, Histone-Lysine N-Methyltransferase, 3. Good health, Cell biology, 030104 developmental biology, Oncology, Histone methyltransferase, Histone Methyltransferases, Epigenetic therapy, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f0fd34332be5f88813a6d939006c6aTest
https://pubmed.ncbi.nlm.nih.gov/30367118Test

المؤلفون: Rosemary Yu, Suzanne Trudel, Aleksandra A. Pandyra, Janice T. Pong, Manpreet Kalkat, Peter J. Mullen, Karl S. Lang, Aaron D. Schimmer, Mark D. Minden, Linda Z. Penn, Zhihua Li

المصدر: Cancer Research. 74:4772-4782

مصطلحات موضوعية: Hydroxymethylglutaryl-CoA Synthase, Male, Cancer Research, Statin, medicine.drug_class, Medizin, Mevalonic Acid, Antineoplastic Agents, Apoptosis, Mevalonic acid, Pharmacology, Biology, Mice, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Dipyridamole, Potentiator, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, Oncology, chemistry, Leukocytes, Mononuclear, lipids (amino acids, peptides, and proteins), Mevalonate pathway, Sterol regulatory element-binding protein 2, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Multiple Myeloma, Sterol Regulatory Element Binding Protein 2, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2261eae78d1bfa3221fb79891532d0bTest
https://doi.org/10.1158/0008-5472.can-14-0130Test