المؤلفون: Mosaad S. Mohamed, Shahenda Mahgoub, Hend Medhat El-Shanbaky, Rania H. Abd El-Hameed, Sahar A. Ali

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 977-986 (2021)

مصطلحات موضوعية: Chemokine, medicine.drug_class, Inflammation, RM1-950, 01 natural sciences, Anti-inflammatory, Lipoxygenase, Structure-Activity Relationship, 4-Butyrolactone, Heterocyclic Compounds, Drug Discovery, medicine, Humans, 15-LOX inhibitors, Lipoxygenase Inhibitors, Pyridazinone, anti-inflammatory, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Tumor Necrosis Factor-alpha, TNF-α inhibitor, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cyclooxygenase 2, biology.protein, Tumor necrosis factor alpha, selective COX-2 inhibitor, Cyclooxygenase, Therapeutics. Pharmacology, medicine.symptom, Research Article, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19667daf6d13bb3c9f348e6d97dfab69Test
http://europepmc.org/articles/PMC8118430Test

المؤلفون: Zongduo Guo, Ping Zhang, Liu Liu, Yongbing Deng, Zhaohui He, Yidan Liang, Hong Chen, Zhaosi Zhang, Xiaochuan Sun

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Male, Aging, subarachnoid hemorrhage, Morpholines, Administration, Oral, Apoptosis, Inflammation, Pharmacology, Phosphatidylinositol 3-Kinases, chemistry.chemical_compound, early brain injury, Downregulation and upregulation, Animals, Humans, Hydroxyurea, Medicine, LY294002, Lipoxygenase Inhibitors, 5-LOX, Protein kinase B, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Neurons, Arachidonate 5-Lipoxygenase, biology, business.industry, Cell Biology, Zileuton, Rats, Disease Models, Animal, Infusions, Intraventricular, chemistry, Chromones, Brain Injuries, Arachidonate 5-lipoxygenase, biology.protein, medicine.symptom, business, Proto-Oncogene Proteins c-akt, Signal Transduction, Research Paper, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab727b90d24c0887f137ed7ce4dbcd6Test
https://doi.org/10.18632/aging.202869Test

المؤلفون: Drago Šubarić, Maja Molnar, Ivica Strelec, Melita Lončarić, Tihomir Moslavac, Valentina Pavić

المصدر: Biomolecules
Biomolecules, Vol 11, Iss 152, p 152 (2021)

مصطلحات موضوعية: plant extracts, Food spoilage, Lipoxygenase, lcsh:QR1-502, Inflammation, Stimulation, Review, Flowers, 01 natural sciences, Biochemistry, lcsh:Microbiology, 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, medicine, Animals, Arachidonate 15-Lipoxygenase, Humans, Lipoxygenase Inhibitors, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Arachidonate 5-Lipoxygenase, Arachidonic Acid, lipoxygenase, polyphenols, biology, fungi, Fatty Acids, food and beverages, Polyphenols, Hydrogen Peroxide, 3. Good health, 0104 chemical sciences, Oxygen, Plant Leaves, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Polyphenol, biology.protein, Fatty Acids, Unsaturated, Arachidonic acid, medicine.symptom, Oxidation-Reduction, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98b336fb16017d9575d9f866f54f9efTest
http://europepmc.org/articles/PMC7911790Test

المؤلفون: Anderson Nogueira Mendes, Francisco das Chagas Pereira de Andrade

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: In silico, Lipoxygenase, Anti-Inflammatory Agents, lcsh:Medicine, Inflammation, Pharmacology, chemistry.chemical_compound, Diclofenac, Anti-Infective Agents, Eugenol, medicine, Humans, Lipoxygenase Inhibitors, lcsh:Science, chemistry.chemical_classification, Aspirin, Multidisciplinary, biology, Cyclooxygenase 2 Inhibitors, lcsh:R, Anti-Inflammatory Agents, Non-Steroidal, Computational Biology, Molecular Docking Simulation, Enzyme, chemistry, Cyclooxygenase 2, biology.protein, Cyclooxygenase 1, lcsh:Q, Cyclooxygenase, medicine.symptom, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc2434b8f7809a2ac14b800f8be949fTest
https://pubmed.ncbi.nlm.nih.gov/33004893Test

المؤلفون: Ewa Habza-Kowalska, Dariusz Dziki, Urszula Gawlik-Dziki

المصدر: Biomolecules
Volume 9
Issue 11
Biomolecules, Vol 9, Iss 11, p 663 (2019)

مصطلحات موضوعية: endocrine system, thyroid peroxidase, dietary polyphenols, Lipoxygenase, lcsh:QR1-502, antioxidant activity, Sinapinic acid, Biochemistry, Iodide Peroxidase, lcsh:Microbiology, Article, Antioxidants, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Thyroid peroxidase, medicine, Food science, Lipoxygenase Inhibitors, Molecular Biology, IC50, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Plant Extracts, food and beverages, Catechin, inhibition, Mechanism of action, 030220 oncology & carcinogenesis, Apigenin, embryonic structures, biology.protein, medicine.symptom, Kaempferol, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d9abe2623f0e66de739659c8475499Test
http://europepmc.org/articles/PMC6920844Test

المؤلفون: Simona Pace, Daniela Schuster, Marc Birringer, Maria Wallert, Christina Weinigel, Hermann Stuppner, Denis Séraphin, David Guilet, Veronika Temml, Martin Raasch, Silke Rummler, Helmut Pein, Fiorentina Roviezzo, Jean-Jacques Helesbeux, Rosella Bilancia, Lidia Sautebin, Stefanie König, Guillaume Viault, Chau-Phi Dinh, Alexia Ville, Ulrike Garscha, Birgit Waltenberger, Alexander S. Mosig, Stefan Lorkowski, Andreas Koeberle, Fabiana Troisi, Pascal Richomme, Oliver Werz, Khaled Alsabil, Antonietta Rossi, Konstantin Neukirch

المساهمون: Pein, Helmut, Ville, Alexia, Pace, Simona, Temml, Veronika, Garscha, Ulrike, Raasch, Martin, Alsabil, Khaled, Viault, Guillaume, Dinh, Chau-Phi, Guilet, David, Troisi, Fabiana, Neukirch, Konstantin, König, Stefanie, Bilancia, Rosella, Waltenberger, Birgit, Stuppner, Hermann, Wallert, Maria, Lorkowski, Stefan, Weinigel, Christina, Rummler, Silke, Birringer, Marc, Roviezzo, Fiorentina, Sautebin, Lidia, Helesbeux, Jean-Jacque, Séraphin, Deni, Mosig, Alexander S., Schuster, Daniela, Rossi, Antonietta, Richomme, Pascal, Werz, Oliver, Koeberle, Andreas, Substances d'Origine Naturelle et Analogues Structuraux (SONAS), Université d'Angers (UA)

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.3834. ⟨10.1038/s41467-018-06158-5⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Metabolite, medicine.medical_treatment, General Physics and Astronomy, Pharmacology, chemistry.chemical_compound, Mice, 0302 clinical medicine, Leukocytes, Vitamin E, Lipoxygenase Inhibitors, lcsh:Science, Multidisciplinary, biology, Chemistry (all), Middle Aged, Recombinant Proteins, 3. Good health, Liver, 030220 oncology & carcinogenesis, Arachidonate 5-lipoxygenase, Metabolome, medicine.symptom, Bronchial Hyperreactivity, Adult, Cell signaling, Adolescent, Cell Survival, Science, Inflammation, Peritonitis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Physics and Astronomy (all), Inhibitory Concentration 50, Young Adult, Immune system, medicine, Animals, Humans, Aged, Biochemistry, Genetics and Molecular Biology (all), Arachidonate 5-Lipoxygenase, Cell-Free System, General Chemistry, Lipid signaling, 030104 developmental biology, chemistry, biology.protein, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfee7afdff0d4990f14ad8886b080055Test
http://link.springer.com/article/10.1038/s41467-018-06158-5Test

المؤلفون: Jin Sun, Xiao-Gang Chen, Shou-Guo Wang, Fu Hua, Hai-Tao Yue, Yong-yi Xu

المصدر: Drug Design, Development and Therapy

مصطلحات موضوعية: Male, Indoles, mice, zafirlukast, Phenylcarbamates, Pharmaceutical Science, Apoptosis, Inflammation, 030204 cardiovascular system & hematology, Pharmacology, Cys-LT, Neuroprotection, Tosyl Compounds, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Animals, Medicine, Lipoxygenase Inhibitors, 030212 general & internal medicine, Zafirlukast, Perylene, Spinal cord injury, Spinal Cord Injuries, Original Research, Sulfonamides, Leukotriene, Drug Design, Development and Therapy, TUNEL assay, pseudohypericin, biology, Tumor Necrosis Factor-alpha, business.industry, medicine.disease, Neutrophil Infiltration, Proto-Oncogene Proteins c-bcl-2, Arachidonate 5-lipoxygenase, biology.protein, 5-lipoxygenase, Leukotriene Antagonists, Drug Therapy, Combination, Tumor necrosis factor alpha, medicine.symptom, Corrigendum, business, medicine.drug

وصف الملف: text/html

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7038cdeee643ee378d0c4460ae0dfdTest
http://europepmc.org/articles/PMC6078184Test

المؤلفون: Akira Higashimori, Tetsuya Tanigawa, Koji Otani, Yasuaki Nagami, Yuji Nadatani, Shuhei Hosomi, Noriko Kamata, Fumio Tanaka, Hiroyuki Kitamura, Shusei Fukunaga, Toshio Watanabe, Takuya Kuzumoto, Yasuhiro Fujiwara, Koichi Taira

المصدر: PLoS ONE, Vol 16, Iss 5, p e0250862 (2021)
PLoS ONE

مصطلحات موضوعية: Male, 0301 basic medicine, Chemokine, NSAIDs, Chemokine CXCL1, Gene Expression, Pharmacology, Mice, White Blood Cells, chemistry.chemical_compound, 0302 clinical medicine, Animal Cells, Intestine, Small, Medicine and Health Sciences, Arachidonate 15-Lipoxygenase, Lipoxygenase Inhibitors, Intestinal Mucosa, Immune Response, Analgesics, Multidisciplinary, biology, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Drugs, Animal Models, Lipids, CXCL1, medicine.anatomical_structure, Pharmaceutical Preparations, Experimental Organism Systems, 030220 oncology & carcinogenesis, Cytokines, Small Intestine, Medicine, Tumor necrosis factor alpha, Anatomy, Cellular Types, medicine.symptom, Research Article, Histology, Docosahexaenoic Acids, Drug-Related Side Effects and Adverse Reactions, Immune Cells, Science, Immunology, Mouse Models, Inflammation, Protective Agents, Research and Analysis Methods, Formyl peptide receptor 2, Proinflammatory cytokine, 03 medical and health sciences, Signs and Symptoms, Model Organisms, Genetics, medicine, Animals, Blood Cells, Macrophages, Biology and Life Sciences, Cell Biology, Pain management, Small intestine, Baicalein, Mice, Inbred C57BL, Gastrointestinal Tract, Disease Models, Animal, 030104 developmental biology, Animal Studies, biology.protein, Clinical Medicine, Digestive System

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c3fe2f7675ab02f7e6472a448a8be2Test
https://doaj.org/article/6bb02232e6194015b5f31de0a4759d2dTest

المؤلفون: Israel Fernández, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, Mourad Chioua, Belén Merás-Sáiz, José Marco-Contelles, María Jesús Oset-Gasque, Beatriz Chamorro, Isabel Iriepa, Daniel González-Nieto, Ricardo Martínez-Murillo, Daniel Diez-Iriepa, David García-Vieira

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Male, 0301 basic medicine, Antioxidant, genetic structures, medicine.medical_treatment, Drug Evaluation, Preclinical, lcsh:Medicine, Apoptosis, Pharmacology, Brain Ischemia, Mice, Neuroblastoma, chemistry.chemical_compound, 0302 clinical medicine, Lipoxygenase Inhibitors, lcsh:Science, Neurons, Multidisciplinary, Molecular Structure, Drug discovery, Chemistry, Superoxide, Infarction, Middle Cerebral Artery, Free Radical Scavengers, Neuroprotection, Neuroprotective Agents, Nitrogen Oxides, medicine.symptom, psychological phenomena and processes, Ischemia, Brain damage, behavioral disciplines and activities, Article, Cyclic N-Oxides, 03 medical and health sciences, In vivo, Cell Line, Tumor, Rotenone, medicine, Animals, lcsh:R, medicine.disease, In vitro, Mice, Inbred C57BL, Oxygen, Disease Models, Animal, Glucose, 030104 developmental biology, nervous system, lcsh:Q, Oligomycins, Lipid Peroxidation, 030217 neurology & neurosurgery, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c656562bee4970b214b0b18755d30aTest
https://doi.org/10.1038/s41598-020-70690-yTest

المؤلفون: Romain A. Colas, Agua Sobrino, Mary Walker, Jesmond Dalli

المصدر: PLOS ONE
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0242543 (2020)

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Male, Mice, Knockout, ApoE, Gene Expression, 030204 cardiovascular system & hematology, Pharmacology, Biochemistry, Vascular Medicine, Mice, White Blood Cells, 0302 clinical medicine, Medical Conditions, Animal Cells, Gene expression, Medicine and Health Sciences, Arachidonate 15-Lipoxygenase, Lipoxygenase Inhibitors, Immune Response, Principal Component Analysis, Multidisciplinary, Chemistry, Eukaryota, Plants, Lipids, Lipoproteins, LDL, Lipoxins, Cell Processes, Medicine, Female, medicine.symptom, Cellular Types, Research Article, Leukotrienes, Algae, Phagocytosis, Science, Immune Cells, Inflammatory Diseases, Primary Cell Culture, Immunology, Inflammation, 03 medical and health sciences, Lipid Mediators, Apolipoproteins E, Signs and Symptoms, Downregulation and upregulation, Fatty Acids, Omega-3, medicine, Animals, Humans, Arachidonate 5-Lipoxygenase, Blood Cells, Macrophages, fungi, Organisms, Biology and Life Sciences, Lipid signaling, Cell Biology, Atherosclerosis, In vitro, 030104 developmental biology, Cell culture, Diet, Western, Dietary Supplements, Prostaglandins, Clinical Medicine, Oils

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5165e1943bf439897bf8b97869c08aceTest