نتائج البحث - "Steven Grant"

1

The conception of the ABCD study: From substance use to a broad NIH collaboration

المصدر: Developmental Cognitive Neuroscience, Vol 32, Iss, Pp 4-7 (2018)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c173d6005321379ef1b5d199bcec12Test
http://www.sciencedirect.com/science/article/pii/S1878929317300725Test

2

Meaningful associations in the adolescent brain cognitive development study

المصدر: Neuroimage
NeuroImage, Vol 239, Iss, Pp 118262-(2021)
NeuroImage, vol 239, iss Am. Psychol. 73 2018

مصطلحات موضوعية: Gerontology, Male, Parents, Longitudinal study, Ethnic group, Medical and Health Sciences, Substance Misuse, 0302 clinical medicine, Cognition, Catchment Area, Health, Models, Cognitive development, Psychology, Prospective Studies, Child, Pediatric, education.field_of_study, 05 social sciences, Brain, Organ Size, Reproducibility, Alcoholism, Mental Health, Hypothesis testing, Neurology, Health, Research Design, Neurological, Cohort, Catchment Area, Female, Clinical psychology, RC321-571, Pediatric Research Initiative, Adolescent, Adolescent brain cognitive development study, Cognitive Neuroscience, Population, Models, Neurological, Psychology, Adolescent, Neurosciences. Biological psychiatry. Neuropsychiatry, Population neuroscience, Models, Psychological, Basic Behavioral and Social Science, 050105 experimental psychology, Sampling Studies, Article, 03 medical and health sciences, Clinical Research, Behavioral and Social Science, Effect Sizes, Genetics, Humans, 0501 psychology and cognitive sciences, Covariate Adjustments, education, Propensity Score, Selection Bias, Neurology & Neurosurgery, Psychology and Cognitive Sciences, Neurosciences, Reproducibility of Results, Adolescent Development, Mental health, United States, Brain Disorders, Good Health and Well Being, Socioeconomic Factors, Sample Size, Psychological, Household income, Gene-Environment Interaction, Generic health relevance, Drug Abuse (NIDA only), Neurocognitive, 030217 neurology & neurosurgery, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae267f3efd5707e9d0df990bda7ac22Test
https://pubmed.ncbi.nlm.nih.gov/34147629Test

3

XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma

المؤلفون: Juan A Gomez, Trinayan Kashyap, Yun Dai, Alexis Bauer, Yosef Landesman, Steven Grant, Jana L. Dawson, Daniel M. Sullivan, Kenneth H. Shain, Joel G. Turner, Mark B. Meads

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Transcription, Genetic, Receptors, Cytoplasmic and Nuclear, Apoptosis, Mice, SCID, Pharmacology, acquired drug resistance, Bortezomib, chemistry.chemical_compound, 0302 clinical medicine, NF-KappaB Inhibitor alpha, immune system diseases, Mice, Inbred NOD, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Multiple myeloma, Hematology, carfilzomib, Protein Stability, NF-kappa B, 3. Good health, multiple myeloma, Gene Expression Regulation, Neoplastic, Hydrazines, Oncology, 030220 oncology & carcinogenesis, XPO1, Female, RNA Interference, Oligopeptides, medicine.drug, Research Paper, medicine.medical_specialty, Proteasome Endopeptidase Complex, Combination therapy, Active Transport, Cell Nucleus, Karyopherins, Transfection, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Cell Nucleus, Dose-Response Relationship, Drug, business.industry, Cancer, Triazoles, medicine.disease, Carfilzomib, Xenograft Model Antitumor Assays, IκBα, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Proteolysis, Cancer research, Proteasome inhibitor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98489c6e2519a954c0d72b3e5c986af8Test
http://europepmc.org/articles/PMC5340237Test

4

Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation

المؤلفون: Masey Ross, Mandy Mayo Aust, Kathryn A. Rizzo, Rebecca E. Parker, Andrea Ferreira-Gonzalez, Catherine I. Dumur, Mohamed Rahmani, Maciej Kmieciak, Leonid B. Reshko, Elisa Hawkins, Steven Grant

المصدر: Haematologica. 100:1553-1563

مصطلحات موضوعية: NPM1, Myeloid, Immunology, bcl-X Protein, Down-Regulation, Mechanistic Target of Rapamycin Complex 2, Mice, SCID, mTORC1, Mechanistic Target of Rapamycin Complex 1, CD38, Biology, Biochemistry, mTORC2, Piperazines, Nitrophenols, Mice, Mice, Inbred NOD, hemic and lymphatic diseases, medicine, Animals, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Benzoxazoles, Sulfonamides, U937 cell, TOR Serine-Threonine Kinases, Biphenyl Compounds, Myeloid leukemia, U937 Cells, Articles, Cell Biology, Hematology, medicine.disease, Xenograft Model Antitumor Assays, Enzyme Activation, Myeloid Cell Leukemia Sequence 1 Protein, Leukemia, Myeloid, Acute, Leukemia, Haematopoiesis, Pyrimidines, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Multiprotein Complexes, Cancer research, Female, Nucleophosmin, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67b6c89b18f1b203856d988ff6e2d3aTest
https://doi.org/10.3324/haematol.2015.130351Test

5

Phase I Trial of Bortezomib (PS-341; NSC 681239) and 'Nonhybrid' (Bolus) Infusion Schedule of Alvocidib (Flavopiridol; NSC 649890) in Patients with Recurrent or Refractory Indolent B-cell Neoplasms

المصدر: Clinical Cancer Research. 20:5652-5662

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Neutropenia, Pharmacology, Article, Drug Administration Schedule, Bortezomib, chemistry.chemical_compound, Piperidines, Recurrence, hemic and lymphatic diseases, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Multiple myeloma, Aged, Flavonoids, B-Lymphocytes, Leukopenia, business.industry, Waldenstrom macroglobulinemia, Middle Aged, Alvocidib, medicine.disease, Boronic Acids, Combined Modality Therapy, Lymphoproliferative Disorders, Regimen, Treatment Outcome, chemistry, Pyrazines, Retreatment, Female, Mantle cell lymphoma, Drug Monitoring, medicine.symptom, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390b15badeec929de98b3fd33b94b857Test
https://doi.org/10.1158/1078-0432.ccr-14-0805Test

6

Pazopanib and HDAC inhibitors interact to kill sarcoma cells

المؤلفون: Hossein A. Hamed, Paul Dent, Steven Grant, Seyedmehrad Tavallai, Andrew Poklepovic

المصدر: Cancer Biology & Therapy. 15:578-585

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c4c52696d45c8d532ac245ed88ab37Test
https://doi.org/10.4161/cbt.28163Test

7

HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells

المؤلفون: Paul Dent, Jane L. Roberts, Nichola Cruickshanks, Steven Grant, Thomas Ridder, Adam Conley, Laurence Booth, Andrew Poklepovic

المصدر: Cancer Biology & Therapy. 15:305-316

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1b8949cb34d62f832ad4256a79ca32Test
https://doi.org/10.4161/cbt.27309Test

8

Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy

المؤلفون: Hossein A. Hamed, Laurence Booth, Seyedmehrad Tavallai, Andrew Poklepovic, Nichola Cruickshanks, Jahangir Syed, Gangadharan B. Sajithlal, Paul Dent, Steven Grant

المصدر: Cancer Biology & Therapy

مصطلحات موضوعية: Cancer Research, Indoles, Receptor, ErbB-2, Cell, Gene Expression, Epigenesis, Genetic, necrosis, Mice, 0302 clinical medicine, anoikis, Anoikis, RNA, Small Interfering, ERBB1, bcl-2-Associated X Protein, BH3 domain, 0303 health sciences, biology, Brain Neoplasms, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, bcl-2 Homologous Antagonist-Killer Protein, Cell killing, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Oncology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Molecular Medicine, Female, Stem cell, signaling, Bcl-2 Homologous Antagonist-Killer Protein, Research Paper, autophagy, tumor, Programmed cell death, Antineoplastic Agents, Hormonal, Cell Survival, NOXA, bcl-X Protein, Mice, Nude, Breast Neoplasms, 03 medical and health sciences, Bcl-2-associated X protein, Proto-Oncogene Proteins, medicine, Animals, Humans, Pyrroles, 030304 developmental biology, Pharmacology, Valproic Acid, BAK, Lapatinib, Xenograft Model Antitumor Assays, Molecular biology, Histone Deacetylase Inhibitors, Drug Resistance, Neoplasm, Quinazolines, biology.protein, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Histone deacetylase, MCL-1, Apoptosis Regulatory Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510c38b3cc6fa102fc9ef09fdf587a5dTest
https://doi.org/10.4161/cbt.26234Test

9

Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling

المؤلفون: Steven Grant, Paul Dent, Jeremy C. Allegood, Andrew Poklepovic, Sarah Spiegel, Besim Ogretmen, Nichola Cruickshanks, Margaret A. Park, Hossein A. Hamed, M. Danielle Bareford

المصدر: Cancer Biology & Therapy. 13:793-803

مصطلحات موضوعية: Niacinamide, MAPK/ERK pathway, Sorafenib, Cancer Research, medicine.medical_specialty, Ceramide, Guanine, MAP Kinase Signaling System, Pyridines, Antineoplastic Agents, Breast Neoplasms, Endosomes, Pemetrexed, Biology, Receptor, Platelet-Derived Growth Factor beta, chemistry.chemical_compound, Glutamates, Cell Line, Tumor, Internal medicine, Autophagy, medicine, Humans, Protein Phosphatase 2, Extracellular Signal-Regulated MAP Kinases, Ceramide synthase, Pharmacology, Phenylurea Compounds, Benzenesulfonates, Drug Synergism, Protein phosphatase 2, Enzyme Activation, src-Family Kinases, Endocrinology, Oncology, chemistry, Gene Knockdown Techniques, Cancer cell, Cancer research, Molecular Medicine, Female, RNA Interference, Research Paper, Proto-oncogene tyrosine-protein kinase Src, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d42773d08083a74b0e4f8a1a6753dcTest
https://doi.org/10.4161/cbt.20562Test

10

Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process

المؤلفون: Mandy Mayo Aust, Elisa Attkisson, Mohamed Rahmani, Andrea Ferreira-Gonzalez, Steven Grant, David C. Williams

المصدر: Blood. 119:6089-6098

مصطلحات موضوعية: Niacinamide, Sorafenib, Indoles, Pyridines, Immunology, Mice, Nude, Apoptosis, HL-60 Cells, Biology, Biochemistry, Mice, chemistry.chemical_compound, Proto-Oncogene Proteins, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Pyrroles, Clonogenic assay, neoplasms, Cells, Cultured, Gene knockdown, Myeloid Neoplasia, Bcl-2-Like Protein 11, Phenylurea Compounds, Benzenesulfonates, Autophagy, Membrane Proteins, Myeloid leukemia, Drug Synergism, U937 Cells, Cell Biology, Hematology, medicine.disease, Xenograft Model Antitumor Assays, Up-Regulation, Leukemia, Proto-Oncogene Proteins c-bcl-2, chemistry, Leukemia, Myeloid, Cancer research, Female, Apoptosis Regulatory Proteins, Obatoclax, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3eeb95b4fed43aa25d02ce71b086dc3Test
https://doi.org/10.1182/blood-2011-09-378141Test

تنقيح النتائج