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المؤلفون: Geetika Singh, Cristina D. Guibao, Jayaraman Seetharaman, Anup Aggarwal, Christy R. Grace, Dan E. McNamara, Sivaraja Vaithiyalingam, M. Brett Waddell, Tudor Moldoveanu
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Nature Communicationsمصطلحات موضوعية: Multidisciplinary, Cell Death, Science, General Physics and Astronomy, Membrane Proteins, Apoptosis, General Chemistry, Crystallography, X-Ray, Ligands, General Biochemistry, Genetics and Molecular Biology, Article, Mitochondria, bcl-2 Homologous Antagonist-Killer Protein, Proto-Oncogene Proteins c-bcl-2, Liposomes, Humans, biological phenomena, cell phenomena, and immunity, BH3 Interacting Domain Death Agonist Protein, X-ray crystallography
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8385f4f44c0480b152b55aa3c2761dTest
https://doaj.orgTest/article /948c7729db444ae0965cb207d8ea6853 -
2Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer
المؤلفون: Barbara Jonchere, Jonathan Low, Michele Connelly, Liying Chi, Sergio C. Chai, R. Kiplin Guy, Kevin W. Freeman, Brandon Young, Jeanine E. Price, Mi-Kyung Yun, Marie Morfouace, Anang A. Shelat, Geoffrey Neale, Rachelle R. Olsen, Nagakumar Bharatham, Daniel Savic, Stephen W. White, P. Jake Slavish, Vincent A. Boyd, Lyudmila Tsurkan, Jun J. Yang, Nancy E. Martinez, Zhenmei Li, Martine F. Roussel, Philip M. Potter, M. Brett Waddell, William R. Shadrick, Richard E. Lee, Taosheng Chen, Sourav Das
المصدر: Cancer Res
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antineoplastic Agents, Context (language use), Mice, SCID, Article, Proto-Oncogene Proteins c-myc, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Cell Line, Tumor, Neoplasms, Neuroblastoma, medicine, Animals, Humans, Child, Cytotoxicity, Oncogene, Chemistry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Pediatric cancer, Bromodomain, 030104 developmental biology, Oncology, Drug development, Drug Design, 030220 oncology & carcinogenesis, Cancer research, Female, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d687ae06b408a0a8a364651477a03fTest
https://doi.org/10.1158/0008-5472.can-19-3934Test -
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المؤلفون: Steven N. Seyedin, Timothy Hoggard, Jiang Liu, Amanda Nourse, Min Zhuang, Michal Hammel, David M. Duda, Kevin P. White, J. Wade Harper, Helen Walden, Matthew F. Calabrese, Darcie J. Miller, Brenda A. Schulman, M. Brett Waddell
المصدر: Molecular Cell. 36(1):39-50
مصطلحات موضوعية: Models, Molecular, Co-Repressor Proteins, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Computational biology, SPOP, Crystallography, X-Ray, Article, Histones, Protein structure, Consensus Sequence, Phosphoprotein Phosphatases, Animals, Drosophila Proteins, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Protein Structure, Quaternary, Molecular Biology, Adaptor Proteins, Signal Transducing, biology, Cullin Proteins, Ubiquitination, Nuclear Proteins, Cell Biology, Peptide Fragments, Chromatin, Ubiquitin ligase, DNA-Binding Proteins, Repressor Proteins, Drosophila melanogaster, Biochemistry, Mutation, biology.protein, Protein Multimerization, Cullin, Molecular Chaperones, Protein Binding, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3c3d9cbf9cfaab45e912fafb9471e2Test