المؤلفون: Guowei Yin, Karin Giller, Markus Zweckstetter, Tiago F. Outeiro, Timo Strohäker, Francesca Munari, Joshua Salafsky, Ben Moree, Diana F. Lázaro, Stefan Becker

المصدر: Journal of Biological Chemistry
The Journal of Biological Chemistry
The journal of biological chemistry 290(46), 27582-27593 (2015). doi:10.1074/jbc.M114.636027

مصطلحات موضوعية: Protein Conformation, animal diseases, pharmacology [Small Molecule Libraries], Protein aggregation, Ligands, Biochemistry, Antiparkinson Agents, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, Neurons, 0303 health sciences, Tumor, Drug discovery, Parkinson Disease, Small molecule, 3. Good health, metabolism [Neurons], ddc:540, chemistry [Antiparkinson Agents], alpha-Synuclein, Parkinson disease, drug discovery, protein aggregation, protein conformation, protein drug interaction, Cell Line, Tumor, Humans, Protein Aggregates, Protein Aggregation, Pathological, Small Molecule Libraries, isolation & purification [Small Molecule Libraries], Molecular Biophysics, chemistry [Small Molecule Libraries], metabolism [Parkinson Disease], Cell Line, 03 medical and health sciences, metabolism [Protein Aggregation, Pathological], Pathological, mental disorders, Molecular Biology, 030304 developmental biology, Alpha-synuclein, pharmacology [Antiparkinson Agents], drug therapy [Protein Aggregation, Pathological], Binding protein, drug effects [Protein Aggregates], Cell Biology, Protein Aggregation, drug therapy [Parkinson Disease], isolation & purification [Antiparkinson Agents], nervous system diseases, drug effects [Protein Conformation], chemistry [alpha-Synuclein], nervous system, chemistry, Biophysics, 030217 neurology & neurosurgery, Protein ligand

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94d4e41f529440ed17d7b805a1a18abTest
https://doi.org/10.1074/jbc.m114.636027Test

المؤلفون: Patrícia Guerreiro, Susana Gonçalves, Salvador Ventura, Evangelia Emmanouilidou, Anna Villar-Piqué, Tiago Antônio de Oliveira Mendes, Flaviano Giorgini, Duarte C. Barral, Tiago F. Outeiro, Zrinka Marijanovic, Oldriska Chutna, Kostas Vekrellis, José S. Ramalho, Jochen Klucken

المصدر: Human Molecular Genetics. 23:6732-6745

مصطلحات موضوعية: Recombinant Fusion Proteins, Endocytic cycle, Biology, Protein aggregation, Exosomes, Transfection, Protein Aggregates, chemistry.chemical_compound, Cell Line, Tumor, Genetics, Humans, Small GTPase, Secretion, RNA, Small Interfering, Molecular Biology, Genetics (clinical), Inclusion Bodies, Neurons, Alpha-synuclein, Synucleinopathies, Biological Transport, General Medicine, 3. Good health, Cell biology, Gene Expression Regulation, chemistry, rab GTP-Binding Proteins, alpha-Synuclein, Signal transduction, Intracellular, Plasmids, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09d3fc061845d548e7717940d3d2750Test
https://doi.org/10.1093/hmg/ddu391Test

المؤلفون: Raquel Pinho, Tomás Lopes da Fonseca, Tiago F. Outeiro

المصدر: Human molecular genetics. 25(14)

مصطلحات موضوعية: 0301 basic medicine, Cathepsin D, Endosomes, Biology, Protein aggregation, medicine.disease_cause, Endoplasmic Reticulum, Protein Aggregation, Pathological, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genetics, medicine, Humans, Protein kinase A, Molecular Biology, Genetics (clinical), Alpha-synuclein, Mutation, Cell Death, Endoplasmic reticulum, Brain, Parkinson Disease, General Medicine, 3. Good health, Proton-Translocating ATPases, 030104 developmental biology, chemistry, Gene Expression Regulation, Cancer research, Unfolded protein response, alpha-Synuclein, Lysosomes, 030217 neurology & neurosurgery, Intracellular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99384c694f1edf2d42e5aa734323d477Test
https://pubmed.ncbi.nlm.nih.gov/27282395Test